| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 14116* | 2021 |
| TLR4 enhances TGF-β signaling and hepatic fibrosis E Seki, S De Minicis, CH Österreicher, J Kluwe, Y Osawa, DA Brenner, ... Nature medicine 13 (11), 1324-1332, 2007 | 2279 | 2007 |
| NF-κB restricts inflammasome activation via elimination of damaged mitochondria Z Zhong, A Umemura, E Sanchez-Lopez, S Liang, S Shalapour, J Wong, ... Cell 164 (5), 896-910, 2016 | 1104 | 2016 |
| New mitochondrial DNA synthesis enables NLRP3 inflammasome activation Z Zhong, S Liang, E Sanchez-Lopez, F He, S Shalapour, X Lin, J Wong, ... Nature 560 (7717), 198-203, 2018 | 994 | 2018 |
| Hepatic inflammation and fibrosis: functional links and key pathways E Seki, RF Schwabe Hepatology 61 (3), 1066-1079, 2015 | 981 | 2015 |
| Toll‐like receptors and adaptor molecules in liver disease: update E Seki, DA Brenner Hepatology 48 (1), 322-335, 2008 | 875 | 2008 |
| Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1β in mice K Miura, Y Kodama, S Inokuchi, B Schnabl, T Aoyama, H Ohnishi, ... Gastroenterology 139 (1), 323-334. e7, 2010 | 869 | 2010 |
| SOCS-1 participates in negative regulation of LPS responses R Nakagawa, T Naka, H Tsutsui, M Fujimoto, A Kimura, T Abe, E Seki, ... Immunity 17 (5), 677-687, 2002 | 818 | 2002 |
| Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2 K Miura, L Yang, N van Rooijen, H Ohnishi, E Seki American Journal of Physiology-Gastrointestinal and Liver Physiology 302 (11 …, 2012 | 587 | 2012 |
| A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches E Seki, DA Brenner, M Karin Gastroenterology 143 (2), 307-320, 2012 | 581 | 2012 |
| ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development H Nakagawa, A Umemura, K Taniguchi, J Font-Burgada, D Dhar, H Ogata, ... Cancer cell 26 (3), 331-343, 2014 | 539 | 2014 |
| Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut E Seki, B Schnabl The Journal of physiology 590 (3), 447-458, 2012 | 538 | 2012 |
| Gene expression profiles during hepatic stellate cell activation in culture and in vivo S De Minicis, E Seki, H Uchinami, J Kluwe, Y Zhang, DA Brenner, ... Gastroenterology 132 (5), 1937-1946, 2007 | 531 | 2007 |
| Toll-like receptor signaling in the liver RF Schwabe, E Seki, DA Brenner Gastroenterology 130 (6), 1886-1900, 2006 | 520 | 2006 |
| CCR1 and CCR5 promote hepatic fibrosis in mice E Seki, S De Minicis, GY Gwak, J Kluwe, S Inokuchi, CA Bursill, JM Llovet, ... The Journal of clinical investigation 119 (7), 1858-1870, 2009 | 512 | 2009 |
| Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling G He, D Dhar, H Nakagawa, J Font-Burgada, H Ogata, Y Jiang, ... Cell 155 (2), 384-396, 2013 | 508 | 2013 |
| CCR2 promotes hepatic fibrosis in mice E Seki, S De Minicis, S Inokuchi, K Taura, K Miyai, N Van Rooijen, ... Hepatology 50 (1), 185-197, 2009 | 495 | 2009 |
| p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells A Umemura, F He, K Taniguchi, H Nakagawa, S Yamachika, ... Cancer cell 29 (6), 935-948, 2016 | 456 | 2016 |
| Heritability of hepatic fibrosis and steatosis based on a prospective twin study R Loomba, N Schork, CH Chen, R Bettencourt, A Bhatt, B Ang, P Nguyen, ... Gastroenterology 149 (7), 1784-1793, 2015 | 427 | 2015 |
| Correlation between liver histology and novel magnetic resonance imaging in adult patients with non‐alcoholic fatty liver disease–MRI accurately quantifies hepatic steatosis in … Z Permutt, TA Le, MR Peterson, E Seki, DA Brenner, C Sirlin, R Loomba Alimentary pharmacology & therapeutics 36 (1), 22-29, 2012 | 411 | 2012 |
David A. BrennerVice Chancellor of Health SciencesVerified email at ucsd.edu