Monoclonal antibody therapies against SARS-CoV-2 D Focosi, S McConnell, A Casadevall, E Cappello, G Valdiserra, ... The Lancet Infectious Diseases 22 (11), e311-e326, 2022 | 218 | 2022 |
Convergent evolution in SARS-CoV-2 spike creates a variant soup from which new COVID-19 waves emerge D Focosi, R Quiroga, S McConnell, MC Johnson, A Casadevall International journal of molecular sciences 24 (3), 2264, 2023 | 104 | 2023 |
Designed protein cages as scaffolds for building multienzyme materials SA McConnell, KA Cannon, C Morgan, R McAllister, BR Amer, RT Clubb, ... ACS Synthetic Biology 9 (2), 381-391, 2020 | 66 | 2020 |
Analysis of immune escape variants from antibody-based therapeutics against COVID-19: a systematic review D Focosi, F Maggi, M Franchini, S McConnell, A Casadevall International journal of molecular sciences 23 (1), 29, 2021 | 57 | 2021 |
Very low levels of remdesivir resistance in SARS-COV-2 genomes after 18 months of massive usage during the COVID19 pandemic: A GISAID exploratory analysis D Focosi, F Maggi, S McConnell, A Casadevall Antiviral research 198, 105247, 2022 | 54 | 2022 |
The Omicron variant of concern: Diversification and convergent evolution in spike protein, and escape from anti-Spike monoclonal antibodies D Focosi, S McConnell, A Casadevall Drug Resistance Updates 65, 100882, 2022 | 48 | 2022 |
Protein Labeling via a Specific Lysine-Isopeptide Bond Using the Pilin Polymerizing Sortase from Corynebacterium diphtheriae SA McConnell, BR Amer, J Muroski, J Fu, C Chang, RR Ogorzalek Loo, ... Journal of the American Chemical Society 140 (27), 8420-8423, 2018 | 41 | 2018 |
Analysis of SARS-CoV-2 mutations associated with resistance to therapeutic monoclonal antibodies that emerge after treatment. D Focosi, S McConnell, DJ Sullivan, A Casadevall Drug Resistance Updates, 100991, 2023 | 35 | 2023 |
Nirmatrelvir and COVID-19: development, pharmacokinetics, clinical efficacy, resistance, relapse, and pharmacoeconomics D Focosi, S McConnell, S Shoham, A Casadevall, F Maggi, G Antonelli International Journal of Antimicrobial Agents 61 (2), 106708, 2023 | 31 | 2023 |
In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking C Chang, BR Amer, J Osipiuk, SA McConnell, IH Huang, V Hsieh, J Fu, ... Proceedings of the National Academy of Sciences 115 (24), E5477-E5486, 2018 | 30 | 2018 |
A glycan FRET assay for detection and characterization of catalytic antibodies to the Cryptococcus neoformans capsule CJ Crawford, MP Wear, DFQ Smith, C d’Errico, SA McConnell, ... Proceedings of the National Academy of Sciences 118 (5), e2016198118, 2021 | 22 | 2021 |
The “Lid” in the Streptococcus pneumoniae SrtC1 Sortase Adopts a Rigid Structure that Regulates Substrate Access to the Active Site AW Jacobitz, EB Naziga, SW Yi, SA McConnell, R Peterson, ME Jung, ... The Journal of Physical Chemistry B 120 (33), 8302-8312, 2016 | 17 | 2016 |
Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture MP Wear, E Jacobs, S Wang, SA McConnell, A Bowen, C Strother, ... Journal of Biological Chemistry 298 (4), 2022 | 16 | 2022 |
Spike mutations in SARS-CoV-2 AY sublineages of the Delta variant of concern: implications for the future of the pandemic D Focosi, F Maggi, S McConnell, A Casadevall Future microbiology 17 (4), 219-221, 2022 | 16 | 2022 |
Spike-protein proteolytic antibodies in COVID-19 convalescent plasma contribute to SARS-CoV-2 neutralization SA McConnell, J Sachithanandham, NJ Mudrak, X Zhu, PA Farhang, ... Cell Chemical Biology 30 (7), 726-738. e4, 2023 | 11 | 2023 |
Kinetics and Optimization of the Lysine–Isopeptide Bond Forming Sortase Enzyme from Corynebacterium diphtheriae CK Sue, SA McConnell, K Ellis-Guardiola, JM Muroski, RA McAllister, ... Bioconjugate chemistry 31 (6), 1624-1634, 2020 | 11 | 2020 |
Similar evolutionary trajectories in an environmental Cryptococcus neoformans isolate after human and murine infection P Sephton-Clark, SA McConnell, N Grossman, RP Baker, Q Dragotakes, ... Proceedings of the National Academy of Sciences 120 (2), e2217111120, 2023 | 9 | 2023 |
Sortase-assembled pili in Corynebacterium diphtheriae are built using a latch mechanism SA McConnell, RA McAllister, BR Amer, BJ Mahoney, CK Sue, C Chang, ... Proceedings of the National Academy of Sciences 118 (12), e2019649118, 2021 | 9 | 2021 |
Synthetic glycans reveal determinants of antibody functional efficacy against a fungal pathogen CJ Crawford, L Guazzelli, SA McConnell, O McCabe, C d’Errico, ... ACS infectious diseases 10 (2), 475-488, 2023 | 7 | 2023 |
Lyophilization induces physicochemical alterations in cryptococcal exopolysaccharide MP Wear, AA Hargett, JE Kelly, SA McConnell, CJ Crawford, ... Carbohydrate polymers 291, 119547, 2022 | 7 | 2022 |