| TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis C Quivoron, L Couronné, V Della Valle, CK Lopez, I Plo, O Wagner-Ballon, ... Cancer cell 20 (1), 25-38, 2011 | 1051 | 2011 |
| Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL Q Wen, B Goldenson, SJ Silver, M Schenone, V Dancik, Z Huang, ... Cell 150 (3), 575-589, 2012 | 167 | 2012 |
| Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models C Thiollier, CK Lopez, B Gerby, C Ignacimouttou, S Poglio, Y Duffourd, ... Journal of Experimental Medicine 209 (11), 2017-2031, 2012 | 115 | 2012 |
| DNMT3AR882H mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice L Scourzic, L Couronné, MT Pedersen, V Della Valle, M Diop, E Mylonas, ... Leukemia 30 (6), 1388-1398, 2016 | 92 | 2016 |
| ETO2-GLIS2 hijacks transcriptional complexes to drive cellular identity and self-renewal in pediatric acute megakaryoblastic leukemia C Thirant, C Ignacimouttou, CK Lopez, L Le Mouël, C Thiollier, A Siret, ... Cancer cell 31 (3), 452-465, 2017 | 88 | 2017 |
| Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification MG Cornejo, V Mabialah, SM Sykes, T Khandan, C Lo Celso, CK Lopez, ... Blood, The Journal of the American Society of Hematology 118 (5), 1264-1273, 2011 | 78 | 2011 |
| B-cell tumor development in Tet2-deficient mice E Mouly, H Ghamlouch, V Della-Valle, L Scourzic, C Quivoron, ... Blood advances 2 (6), 703-714, 2018 | 55 | 2018 |
| Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene–driven myeloid leukemia CK Lopez, E Noguera, V Stavropoulou, E Robert, Z Aid, P Ballerini, ... Cancer discovery 9 (12), 1736-1753, 2019 | 53 | 2019 |
| AIF loss deregulates hematopoiesis and reveals different adaptive metabolic responses in bone marrow cells and thymocytes L Cabon, A Bertaux, MN Brunelle-Navas, I Nemazanyy, L Scourzic, ... Cell Death & Differentiation 25 (5), 983-1001, 2018 | 46 | 2018 |
| Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers A Fagnan, FO Bagger, MR Piqué-Borràs, C Ignacimouttou, A Caulier, ... Blood, The Journal of the American Society of Hematology 136 (6), 698-714, 2020 | 45 | 2020 |
| Pediatric acute megakaryoblastic leukemia: multitasking fusion proteins and oncogenic cooperations CK Lopez, S Malinge, M Gaudry, OA Bernard, T Mercher Trends in Cancer 3 (9), 631-642, 2017 | 24 | 2017 |
| In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis D Lara-Astiaso, A Goñi-Salaverri, J Mendieta-Esteban, N Narayan, ... Nature genetics 55 (9), 1542-1554, 2023 | 17 | 2023 |
| Screening of ETO2-GLIS2–induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia S Benbarche, CK Lopez, E Salataj, Z Aid, C Thirant, MC Laiguillon, ... Science advances 8 (6), eabg9455, 2022 | 15 | 2022 |
| Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia C Thirant, C Lopez, S Malinge, T Mercher Molecular & cellular oncology 4 (6), e1345351, 2017 | 15 | 2017 |
| The Pediatric Acute Leukemia Fusion Oncogene ETO2‐GLIS2 Increases Self‐Renewal and Alters Differentiation in a Human Induced Pluripotent Stem Cells‐Derived Model SN Bertuccio, F Boudia, M Cambot, CK Lopez, L Lordier, A Donada, ... HemaSphere 4 (1), e319, 2020 | 14 | 2020 |
| Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models P Rivera-Munoz, AP Laurent, A Siret, CK Lopez, C Ignacimouttou, ... Blood advances 2 (13), 1616-1627, 2018 | 12 | 2018 |
| Integrative screening approach identifies regulators of polyploidization and targets for acute megakaryocytic leukemia Q Wen, B Goldenson, SJ Silver, M Schenone, V Dancik, Z Huang, ... Cell 150 (3), 575, 2012 | 12 | 2012 |
| HOXA9 forms a repressive complex with nuclear matrix–associated protein SAFB to maintain acute myeloid leukemia S Agrawal-Singh, J Bagri, G Giotopoulos, DMA Azazi, SJ Horton, ... Blood 141 (14), 1737-1754, 2023 | 9 | 2023 |
| High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2:: GLIS2 pediatric leukemia Z Aid, E Robert, CK Lopez, M Bourgoin, F Boudia, M Le Mene, J Riviere, ... Leukemia 37 (3), 571-579, 2023 | 7 | 2023 |
| JAM-C/Jam-C expression is primarily expressed in mouse hematopoietic stem cells E Henry, V Barroca, CK Lopez, M Aurrand-Lions, D Lewandowski, ... HemaSphere 5 (7), e594, 2021 | 1 | 2021 |
