| Guanidinium export is the primal function of SMR family transporters AA Kermani, CB Macdonald, R Gundepudi, RB Stockbridge Proceedings of the National Academy of Sciences 115 (12), 3060-3065, 2018 | 90 | 2018 |
| The structural basis of promiscuity in small multidrug resistance transporters AA Kermani, CB Macdonald, OE Burata, BB Koff, A Koide, E Denbaum, ... Nature Communications 11 (1), 1-9, 2020 | 45 | 2020 |
| DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... Genome biology 24 (1), 36, 2023 | 36 | 2023 |
| Antineoplastic agents. 599. Total synthesis of dolastatin 16 GR Pettit, TH Smith, PM Arce, EJ Flahive, CR Anderson, JC Chapuis, ... Journal of natural products 78 (3), 476-485, 2015 | 27 | 2015 |
| Still rocking in the structural era: a molecular overview of the Small Multidrug Resistance (SMR) transporter family OE Burata, TJ Yeh, CB Macdonald, RB Stockbridge Journal of Biological Chemistry 298 (10), 2022 | 26 | 2022 |
| A topologically diverse family of fluoride channels CB Macdonald, RB Stockbridge Current Opinion in Structural Biology 45, 142-149, 2017 | 22 | 2017 |
| The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics SW Yee, CB Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, ... Molecular Cell 84 (10), 1932-1947. e10, 2024 | 12 | 2024 |
| Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain GO Estevam, EM Linossi, CB Macdonald, CA Espinoza, JM Michaud, ... eLife 12, RP91619, 2024 | 10 | 2024 |
| The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics SW Yee, C Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, DB Silva, ... bioRxiv, 2023 | 8 | 2023 |
| Antineoplastic agents. 600. from the south pacific ocean to the silstatins GR Pettit, PM Arce, JC Chapuis, CB Macdonald Journal of natural products 78 (3), 510-523, 2015 | 8 | 2015 |
| Rosace: a robust deep mutational scanning analysis framework employing position and mean-variance shrinkage J Rao, R Xin, C Macdonald, MK Howard, GO Estevam, SW Yee, M Wang, ... Genome Biology 25 (1), 138, 2024 | 7 | 2024 |
| Molecular basis of proton-sensing by G protein-coupled receptors MK Howard, N Hoppe, XP Huang, CB Macdonald, E Mehrota, PR Grimes, ... bioRxiv, 2024 | 6 | 2024 |
| Deep Insertion, Deletion, and Missense Mutation Libraries for Exploring Protein Variation in Evolution, Disease, and Biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... bioRxiv, 2022.07. 26.501589, 2022 | 4 | 2022 |
| Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning GO Estevam, EM Linossi, J Rao, CB Macdonald, A Ravikumar, ... bioRxiv, 2024 | 1 | 2024 |
| DIMPLE library generation and assembly protocol C Macdonald, D Nedrud, PR Grimes, D Trinidad, C Shin, J Fraser, ... | 1 | 2023 |
| Rosace-AA: Enhancing Interpretation of Deep Mutational Scanning Data with Amino Acid Substitution and Position-Specific Insights J Rao, M Wang, MK Howard, C Macdonald, J Fraser, W Coyote-Maestas, ... bioRxiv, 2025.01. 09.632281, 2025 | | 2025 |
| A Suite of Foundation Models Captures the Contextual Interplay Between Codons M Naghipourfar, S Chen, M Howard, C Macdonald, A Saberi, T Hagen, ... bioRxiv, 2024 | | 2024 |
| Deep mutational scanning of EccD3 reveals the molecular basis of its essentiality in the mycobacterium ESX secretion system DD Trinidad, CB Macdonald, OS Rosenberg, JS Fraser, ... bioRxiv, 2024 | | 2024 |
| Studying protein variation in evolution, disease, and biology through deep insertion, deletion, and missense mutational scanning CB Macdonald Biophysical Journal 122 (3), 519a, 2023 | | 2023 |
| Substrate Recognition of the Small Multidrug Resistance (SMR) Family OE Burata, CB Macdonald, AA Kermani, R Stockbridge Biophysical Journal 120 (3), 212a, 2021 | | 2021 |
