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Raitis Bobrovs
Raitis Bobrovs
Latvian Institute of Organic synthesis
Verified email at osi.lv
Title
Cited by
Cited by
Year
The reluctant polymorph: investigation into the effect of self-association on the solvent mediated phase transformation and nucleation of theophylline
R Bobrovs, L Seton, N Dempster
CrystEngComm 17 (28), 5237-5251, 2015
582015
Potent SARS-CoV-2 mRNA cap methyltransferase inhibitors by bioisosteric replacement of methionine in SAM cosubstrate
O Bobileva, R Bobrovs, I Kanepe, L Patetko, G Kalnins, M Sisovs, AL Bula, ...
ACS Medicinal Chemistry Letters 12 (7), 1102-1107, 2021
512021
Targeting bacterial Sortase A with covalent inhibitors: 27 new starting points for structure-based hit-to-lead optimization
K Jaudzems, V Kurbatska, A Je̅kabsons, R Bobrovs, Z Rudevica, ...
ACS Infectious Diseases 6 (2), 186-194, 2019
352019
Discovery of SARS-CoV-2 Nsp14 and Nsp16 methyltransferase inhibitors by high-throughput virtual screening
R Bobrovs, I Kanepe, N Narvaiss, L Patetko, G Kalnins, M Sisovs, AL Bula, ...
Pharmaceuticals 14 (12), 1243, 2021
332021
Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D
R Zogota, L Kinena, C Withers-Martinez, MJ Blackman, R Bobrovs, ...
European Journal of Medicinal Chemistry 163, 344-352, 2019
272019
Solvent-mediated phase transformation between two tegafur polymorphs in several solvents
R Bobrovs, L Seton, A Actiņš
CrystEngComm 16 (46), 10581-10591, 2014
272014
Polymorph-Selective Role of Hydrogen Bonding and π–π Stacking in p-Aminobenzoic Acid Solutions
R Bobrovs, L Drunka, AA Auzins, K Jaudzems, M Salvalaglio
Crystal Growth & Design 21 (1), 436-448, 2020
262020
Ultrafast Fragment Screening Using Photo-Hyperpolarized (CIDNP) NMR
F Torres, M Bütikofer, GR Stadler, A Renn, H Kadavath, R Bobrovs, ...
Journal of the American Chemical Society 145 (22), 12066-12080, 2023
232023
Exploiting structural dynamics to design open-flap inhibitors of malarial aspartic proteases
R Bobrovs, K Jaudzems, A Jirgensons
Journal of Medicinal Chemistry 62 (20), 8931-8950, 2019
232019
3-(adenosylthio) benzoic acid derivatives as SARS-CoV-2 nsp14 methyltransferase inhibitors
O Bobileva, R Bobrovs, EE Sirma, I Kanepe, AL Bula, L Patetko, ...
Molecules 28 (2), 768, 2023
162023
Formation and transformations of organic salt hydrates: Four encenicline hydrochloride monohydrates and respective isostructural desolvates
R Bobrovs, A Kons, A Berzins, T Rekis, A Actins
Crystal Growth & Design 18 (4), 2100-2111, 2018
152018
2-Aminoquinazolin-4 (3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity
D Rasina, G Stakanovs, OV Borysov, T Pantelejevs, R Bobrovs, ...
Bioorganic & Medicinal Chemistry 26 (9), 2488-2500, 2018
132018
Azole‐based non‐peptidomimetic plasmepsin inhibitors
L Kinena, G Leitis, I Kanepe‐Lapsa, R Bobrovs, K Jaudzems, V Ozola, ...
Archiv der Pharmazie 351 (9), 1800151, 2018
112018
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain
R Kumar, T Le Marchand, L Adam, R Bobrovs, G Chen, J Fridmanis, ...
Nature Communications 15 (1), 965, 2024
92024
Three anhydrous forms and a dihydrate form of quifenadine hydrochloride: a structural study of the thermodynamic stability and dehydration mechanism
A Kons, L Rutkovska, A Bērziņš, R Bobrovs, A Actiņš
CrystEngComm 17 (19), 3627-3635, 2015
92015
trans-Fluorine Effect in Cyclopropane: Diastereoselective Synthesis of Fluorocyclopropyl Cabozantinib Analogs
J Veliks, M Videja, A Kinens, R Bobrovs, M Priede, J Kuka
ACS Medicinal Chemistry Letters 11 (11), 2146-2150, 2020
82020
Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
V Kovada, C Withers-Martinez, R Bobrovs, H Ce̅rule, E Liepins, ...
Journal of Medicinal Chemistry 66 (15), 10658-10680, 2023
72023
Interactions between s100a9 and alpha-synuclein: insight from NMR spectroscopy
Z Toleikis, R Bobrovs, A Janoniene, A Lends, M Ziaunys, I Baronaite, ...
International journal of molecular sciences 23 (12), 6781, 2022
72022
Organic solvents vapor pressure and relative humidity effects on the phase transition rate of α and β forms of tegafur
S Petkune, R Bobrovs, A Actiņ š
Pharmaceutical Development and Technology 17 (5), 625-631, 2012
72012
Exploring aspartic protease inhibitor binding to design selective antimalarials
R Bobrovs, EE Basens, L Drunka, I Kanepe, S Matisone, KK Velins, ...
Journal of Chemical Information and Modeling 62 (13), 3263-3273, 2022
52022
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