| Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins MA Davare, A Saborowski, CA Eide, C Tognon, RL Smith, J Elferich, ... Proceedings of the National Academy of Sciences 110 (48), 19519-19524, 2013 | 153 | 2013 |
| Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context H Wang, J Elferich, E Gouaux Nature structural & molecular biology 19 (2), 212-219, 2012 | 131 | 2012 |
| Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5 J Ge, J Elferich, A Goehring, H Zhao, P Schuck, E Gouaux Elife 7, e38770, 2018 | 95 | 2018 |
| An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I JD Dikeakos, L Thomas, G Kwon, J Elferich, U Shinde, G Thomas Molecular biology of the cell 23 (11), 2184-2197, 2012 | 81 | 2012 |
| Molecular mechanism of prestin electromotive signal amplification J Ge, J Elferich, S Dehghani-Ghahnaviyeh, Z Zhao, M Meadows, ... Cell 184 (18), 4669-4679. e13, 2021 | 75 | 2021 |
| Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein Y Li, XX Sun, J Elferich, U Shinde, LL David, MS Dai Journal of Biological Chemistry 289 (8), 5097-5108, 2014 | 65 | 2014 |
| Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes MM Hosseini, SE Kurtz, S Abdelhamed, S Mahmood, MA Davare, ... Leukemia 32 (11), 2374-2387, 2018 | 64 | 2018 |
| Conformational selection in substrate recognition by Hsp70 chaperones M Marcinowski, M Rosam, C Seitz, J Elferich, J Behnke, C Bello, MJ Feige, ... Journal of molecular biology 425 (3), 466-474, 2013 | 61 | 2013 |
| Mutant calreticulin‐expressing cells induce monocyte hyperreactivity through a paracrine mechanism MR Garbati, CA Welgan, SH Landefeld, LF Newell, A Agarwal, JB Dunlap, ... American journal of hematology 91 (2), 211-219, 2016 | 46 | 2016 |
| Identification of the intracellular gate for a member of the equilibrative nucleoside transporter (ENT) family R Valdés, J Elferich, U Shinde, SM Landfear Journal of Biological Chemistry 289 (13), 8799-8809, 2014 | 41 | 2014 |
| Cotranslational folding inhibits translocation from within the ribosome–Sec61 translocon complex BJ Conti, J Elferich, Z Yang, U Shinde, WR Skach Nature structural & molecular biology 21 (3), 228-235, 2014 | 37 | 2014 |
| The mechanism by which a propeptide-encoded pH sensor regulates spatiotemporal activation of furin DM Williamson, J Elferich, P Ramakrishnan, G Thomas, U Shinde Journal of Biological Chemistry 288 (26), 19154-19165, 2013 | 32 | 2013 |
| KHARON1 mediates flagellar targeting of a glucose transporter in Leishmania mexicana and is critical for viability of infectious intracellular amastigotes KD Tran, D Rodriguez-Contreras, DP Vieira, PA Yates, L David, W Beatty, ... Journal of Biological Chemistry 288 (31), 22721-22733, 2013 | 26 | 2013 |
| Putting the pieces together: the hair cell transduction complex JR Holt, M Tobin, J Elferich, E Gouaux, A Ballesteros, Z Yan, ZM Ahmed, ... Journal of the Association for Research in Otolaryngology, 1-8, 2021 | 21 | 2021 |
| Mechanism of fine-tuning pH sensors in proprotein convertases: identification of a pH-sensing histidine pair in the propeptide of proprotein convertase 1/3 DM Williamson, J Elferich, U Shinde Journal of Biological Chemistry 290 (38), 23214-23225, 2015 | 20 | 2015 |
| Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of Leishmania donovani pyrimidine auxotrophs R Soysa, ZN Wilson, J Elferich, I Forquer, U Shinde, MK Riscoe, PA Yates, ... Journal of Biological Chemistry 288 (41), 29954-29964, 2013 | 16 | 2013 |
| Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography J Elferich, S Clark, J Ge, A Goehring, A Matsui, E Gouaux Elife 10, e74512, 2021 | 14 | 2021 |
| Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections J Elferich, G Schiroli, DT Scadden, N Grigorieff Elife 11, e80980, 2022 | 9 | 2022 |
| Determination of Histidine pKa Values in the Propeptides of Furin and Proprotein Convertase 1/3 Using Histidine Hydrogen–Deuterium Exchange Mass … J Elferich, DM Williamson, LL David, U Shinde Analytical chemistry 87 (15), 7909-7917, 2015 | 9 | 2015 |
| Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses A Matsui, C Spangler, J Elferich, M Shiozaki, N Jean, X Zhao, M Qin, ... ELife 13, RP98458, 2024 | 7 | 2024 |
Eric GouauxSenior scientist, Oregon Health and Science UniversityVerified email at ohsu.edu