| Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line I Zaki, MK Abdelhameid, IM El-Deen, AHAA Wahab, AM Ashmawy, ... European Journal of Medicinal Chemistry 156, 563-579, 2018 | 64 | 2018 |
| Statistical optimization of bile salt deployed nanovesicles as a potential platform for oral delivery of piperine: accentuated antiviral and anti-inflammatory activity in MERS … MY Zakaria, E Fayad, F Althobaiti, I Zaki, AH Abu Almaaty Drug Delivery 28 (1), 1150-1165, 2021 | 34 | 2021 |
| Design, synthesis, and cytotoxic screening of novel azole derivatives on hepatocellular carcinoma (HepG2 Cells) MK Abdelhameid, I Zaki, MR Mohammed, KO Mohamed Bioorganic chemistry 101, 103995, 2020 | 31 | 2020 |
| ‘Poly phenolic phytoceutical loaded nano-bilosomes for enhanced caco-2 cell permeability and SARS-CoV 2 antiviral activity’: in-vitro and insilico studies MY Zakaria, SM Abd El-Halim, BY Beshay, I Zaki, MAS Abourehab Drug Delivery 30 (1), 2162157, 2023 | 26 | 2023 |
| A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies KO Mohamed, I Zaki, IM El-Deen, MK Abdelhameid Bioorganic Chemistry 84, 399-409, 2019 | 23 | 2019 |
| Design and synthesis of newly synthesized acrylamide derivatives as potential chemotherapeutic agents against MCF-7 breast cancer cell line lodged on PEGylated bilosomal nano … I Zaki, RAI Abou-Elkhair, AH Abu Almaaty, O A Abu Ali, E Fayad, ... Pharmaceuticals 14 (10), 1021, 2021 | 21 | 2021 |
| Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2′,3′:4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer … MAE Mourad, A Abo Elmaaty, I Zaki, AAE Mourad, A Hofni, AE Khodir, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2205043, 2023 | 20 | 2023 |
| Synthesis and cytotoxicity screening of some synthesized hybrid nitrogen molecules as anticancer agents AAE Mourad, YW Rizzk, I Zaki, FZ Mohammed, M El Behery Journal of Molecular Structure 1242, 130722, 2021 | 19 | 2021 |
| Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors HM Abd El-Lateef, AA Elmaaty, LMA Abdel Ghany, MS Abdel-Aziz, I Zaki, ... ACS omega 8 (20), 17948-17965, 2023 | 17 | 2023 |
| Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and antiproliferative activity I Zaki, AMY Moustafa, BY Beshay, RE Masoud, MAI Elbastawesy, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 2679-2701, 2022 | 16 | 2022 |
| 5-Aryl-1-Arylideneamino-1H-Imidazole-2(3H)-Thiones: Synthesis and In Vitro Anticancer Evaluation AH Abu Almaaty, EEM Toson, ESH El-Sayed, MAM Tantawy, E Fayad, ... Molecules 26 (6), 1706, 2021 | 16 | 2021 |
| Design, synthesis and cytotoxicity screening of new synthesized pyrimidine-5-carbonitrile derivatives showing marked apoptotic effect I Zaki, RE Masoud, MMS Hamoud, OAA Ali, M Abualnaja, E Fayad, ... Journal of Molecular Structure 1259, 132749, 2022 | 14 | 2022 |
| Boosting the anti MERS-CoV activity and oral bioavailability of resveratrol via PEG-stabilized emulsomal nano-carrier: factorial design, in-vitro and in-vivo assessments MY Zakaria, I Zaki, M Alhomrani, AS Alamri, O Abdulaziz, MAS Abourehab Drug Delivery 29 (1), 3155-3167, 2022 | 12 | 2022 |
| Design, synthesis and cytotoxicity screening of new thiazole derivatives as potential anticancer agents through VEGFR-2 inhibition T Al-Warhi, M Abualnaja, OA Abu Ali, NM Alyamani, FG Elsaid, AA Shati, ... Symmetry 14 (9), 1814, 2022 | 12 | 2022 |
| Design, synthesis and antimicrobial activity of novel quinoline-2-one hybrids as promising DNA gyrase and topoisomerase IV inhibitors MAI Elbastawesy, FAM Mohamed, I Zaki, MI Alahmdi, SS Alzahrani, ... Journal of Molecular Structure 1278, 134902, 2023 | 11 | 2023 |
| Design, Synthesis, Docking Study, and Antiproliferative Evaluation of Novel Schiff Base–Benzimidazole Hybrids with VEGFR-2 Inhibitory Activity HM Abd El-Lateef, MAI Elbastawesy, TM Abdelghani Ibrahim, MM Khalaf, ... Molecules 28 (2), 481, 2023 | 11 | 2023 |
| In vitro anticancer evaluation of some synthesized 2H-quinolinone and halogenated 2H-quinolinone derivatives as therapeutic agents RMA El-Aziz, I Zaki, IM El-Deen, MS Abd-Rahman, FZ Mohammed Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2020 | 11 | 2020 |
| Design, synthesis, and cytotoxicity screening of new synthesized imidazolidine‐2‐thiones as VEGFR‐2 enzyme inhibitors I Zaki, HMM Ramadan, ESH El‐Sayed, M Abd El‐Moneim Archiv der Pharmazie 353 (11), 2000121, 2020 | 11 | 2020 |
| Synthesis and biological activity screening of newly synthesized trimethoxyphenyl-based analogues as potential anticancer agents T Al-Warhi, M Abualnaja, OA Abu Ali, F Althobaiti, F Alharthi, FG Elsaid, ... Molecules 27 (14), 4621, 2022 | 10 | 2022 |
| Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production … LMAA Ghany, BY Beshay, AM Youssef Moustafa, AHA Maghrabi, EHK Ali, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2243551, 2023 | 9 | 2023 |
