The Rac GTPase in cancer: from old concepts to new paradigms MG Kazanietz, MJ Caloca Cancer research 77 (20), 5445-5451, 2017 | 192 | 2017 |
Exchange factors of the RasGRP family mediate Ras activation in the Golgi MJ Caloca, JL Zugaza, XR Bustelo Journal of Biological Chemistry 278 (35), 33465-33473, 2003 | 180 | 2003 |
Structural determinants for the biological activity of Vav proteins JL Zugaza, MA López-Lago, MJ Caloca, M Dosil, N Movilla, XR Bustelo Journal of Biological Chemistry 277 (47), 45377-45392, 2002 | 150 | 2002 |
β2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters MJ Caloca, N Fernandez, NE Lewin, D Ching, R Modali, PM Blumberg, ... Journal of Biological Chemistry 272 (42), 26488-26496, 1997 | 139 | 1997 |
β2-Chimaerin is a novel target for diacylglycerol: binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain MJ Caloca, ML Garcia-Bermejo, PM Blumberg, NE Lewin, E Kremmer, ... Proceedings of the National Academy of Sciences 96 (21), 11854-11859, 1999 | 132 | 1999 |
Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of β2-chimaerin, a ‘non-protein kinase C’phorbol ester receptor MJ Caloca, HB Wang, MG Kazanietz Biochemical Journal 375 (2), 313-321, 2003 | 125 | 2003 |
Phorbol esters and related analogs regulate the subcellular localization of β2-chimaerin, a non-protein kinase C phorbol ester receptor MJ Caloca, HB Wang, A Delemos, S Wang, MG Kazanietz Journal of Biological Chemistry 276 (21), 18303-18312, 2001 | 105 | 2001 |
Vav mediates Ras stimulation by direct activation of the GDP/GTP exchange factor Ras GRP1 MJ Caloca, JL Zugaza, D Matallanas, P Crespo, XR Bustelo The EMBO journal, 2003 | 93 | 2003 |
Pharmacology of the receptors for the phorbol ester tumor promoters: Multiple receptors with different biochemical properties MG Kazanietz, MJ Caloca, P Eroles, T Fujii, ML García-Bermejo, M Reilly, ... Biochemical Pharmacology 60 (10), 1417-1424, 2000 | 93 | 2000 |
F-actin-dependent Translocation of the Rap1 GDP/GTP Exchange Factor RasGRP2 MJ Caloca, JL Zugaza, M Vicente-Manzanares, F Sánchez-Madrid, ... Journal of Biological Chemistry 279 (19), 20435-20446, 2004 | 63 | 2004 |
Activation of Vav by the gammaherpesvirus M2 protein contributes to the establishment of viral latency in B lymphocytes L Rodrigues, M Pires de Miranda, MJ Caloca, XR Bustelo, JP Simas Journal of virology 80 (12), 6123-6135, 2006 | 60 | 2006 |
Inverted signaling hierarchy between RAS and RAC in T-lymphocytes JL Zugaza, MJ Caloca, XR Bustelo Oncogene 23 (34), 5823-5833, 2004 | 47 | 2004 |
Phosphorylation of the Catalytic Subunit of Rat Renal Na+,K+-ATPase by Classical PKC Isoforms MG Kazanietz, MJ Caloca, O Aizman, S Nowicki Archives of biochemistry and biophysics 388 (1), 74-80, 2001 | 46 | 2001 |
Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling MJ Caloca, P Delgado, B Alarcón, XR Bustelo Cellular signalling 20 (4), 758-770, 2008 | 37 | 2008 |
Caspase-mediated cleavage of the TIAM1 guanine nucleotide exchange factor during apoptosis H Qi, P Juo, J Masuda-Robens, MJ Caloca, H Zhou, N Stone, ... | 35 | 2001 |
Minigene Splicing Assays Identify 12 Spliceogenic Variants of BRCA2 Exons 14 and 15 E Fraile-Bethencourt, A Valenzuela-Palomo, B Díez-Gómez, MJ Caloca, ... Frontiers in genetics 10, 503, 2019 | 33 | 2019 |
The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic V Casado-Medrano, MJ Baker, C Lopez-Haber, M Cooke, S Wang, ... Biochemical Society Transactions 46 (4), 1003-1012, 2018 | 30 | 2018 |
Interaction of the Novel Anthracycline Antitumor Agent N-Benzyladriamycin-14-valerate with the C1-Regulatory Domain of Protein Kinase C: Structural … JB Roaten, MG Kazanietz, MJ Caloca, PJ Bertics, L Lothstein, AL Parrill, ... Molecular cancer therapeutics 1 (7), 483-492, 2002 | 30 | 2002 |
Atypical protein kinase C-zeta stimulates thyrotropin-independent proliferation in rat thyroid cells N Fernandez, MJ Caloca, GV Prendergast, JL Meinkoth, MG Kazanietz Endocrinology 141 (1), 146-152, 2000 | 27 | 2000 |
A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression V Casado-Medrano, L Barrio-Real, G García-Rostán, M Baumann, ... Oncotarget 7 (19), 28301, 2016 | 26 | 2016 |