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Shong Lau
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Generation of induced neurons via direct conversion in vivo
O Torper, U Pfisterer, DA Wolf, M Pereira, S Lau, J Jakobsson, ...
Proceedings of the National Academy of Sciences 110 (17), 7038-7043, 2013
5072013
Aging in a dish: iPSC-derived and directly induced neurons for studying brain aging and age-related neurodegenerative diseases
J Mertens, D Reid, S Lau, Y Kim, FH Gage
Annual review of genetics 52 (1), 271-293, 2018
2632018
In vivo reprogramming of striatal NG2 glia into functional neurons that integrate into local host circuitry
O Torper, DR Ottosson, M Pereira, S Lau, T Cardoso, S Grealish, ...
Cell reports 12 (3), 474-481, 2015
2152015
REST suppression mediates neural conversion of adult human fibroblasts via microRNA‐dependent and‐independent pathways
J Drouin‐Ouellet, S Lau, PL Brattås, D Rylander Ottosson, K Pircs, ...
EMBO molecular medicine 9 (8), 1117-1131, 2017
1142017
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
DA Reid, PJ Reed, JCM Schlachetzki, II Nitulescu, G Chou, EC Tsui, ...
Science 372 (6537), 91-94, 2021
962021
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain
M Pereira, U Pfisterer, D Rylander, O Torper, S Lau, M Lundblad, ...
Scientific reports 4 (1), 6330, 2014
652014
Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors
S Lau, DR Ottosson, J Jakobsson, M Parmar
Cell Reports 9 (5), 1673-1680, 2014
412014
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
S Stern, S Lau, A Manole, I Rosh, MM Percia, R Ben Ezer, MN Shokhirev, ...
npj Parkinson's Disease 8 (1), 103, 2022
322022
Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons
M Birtele, Y Sharma, S Kidnapillai, S Lau, TB Stoker, RA Barker, ...
FEBS letters 593 (23), 3370-3380, 2019
202019
Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons
M van den Hurk, S Lau, MC Marchetto, J Mertens, S Stern, O Corti, A Brice, ...
npj Parkinson's Disease 8 (1), 134, 2022
162022
Reduced synaptic activity and dysregulated extracellular matrix pathways are common phenotypes in midbrain neurons derived from sporadic and mutation-associated Parkinson’s …
S Stern, S Lau, A Manole, I Rosh, M Percia, RB Ezer, MN Shokhirev, F Qiu, ...
Biorxiv, 2021.12. 31.474654, 2022
52022
Identification of an age-related Parkinson's disease risk factor that regulates sulfur metabolism
S Lau, S Stern, S Linker, I Da Silva, N Nakatsuka, J Tampé, ...
42021
Advances in neural reprogramming, disease modeling and therapeutic insights
S Lau, S Stern
Frontiers in Aging Neuroscience 15, 1259765, 2023
22023
OPEN ACCESS EDITED BY
S Lau, N Olova, AOJ Fakoya, RP Thummer, KK Haridhasapavalan, ...
Advances in neural reprogramming, disease modeling and therapeutic insights, 73, 2023
2023
OPEN ACCESS EDITED BY
QB Cass, S Chandra, RS Phillips, LW Tinoco, LW Tinoco, ...
The protagonism of bioanalytical methods in high-throughput drug discovery, 28, 2023
2023
Systems
M Parmar, J Jakobsson, J Drouin-Ouellet, S Lau
US Patent App. 16/610,787, 2020
2020
In vivo reprogramming of striatal NG2 glia into functional neurons that integrate into local host circuitry
M Parmar, O Torper, DR Ottosson, S Lau, T Cardoso, S Grealish
GLIA 63, E63-E63, 2015
2015
Effect of Valproic Acid on Stem Cell Development and Functional Recovery of Ischemic Mice
S Lau
Chinese University of Hong Kong, 2012
2012
DNA Transformation and Fermentation Study of Acremonium Chrysogenum
S Lau
Chinese University of Hong Kong, 2007
2007
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Articles 1–19