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Daniel Nomura
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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
K Bersuker, JM Hendricks, Z Li, L Magtanong, B Ford, PH Tang, ...
Nature 575 (7784), 688-692, 2019
26432019
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
DK Nomura, JZ Long, S Niessen, HS Hoover, SW Ng, BF Cravatt
Cell 140 (1), 49-61, 2010
11252010
Exogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state
L Magtanong, PJ Ko, M To, JY Cao, GC Forcina, A Tarangelo, CC Ward, ...
Cell chemical biology 26 (3), 420-432. e9, 2019
8282019
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
DK Nomura, BE Morrison, JL Blankman, JZ Long, SG Kinsey, ...
Science 334 (6057), 809-813, 2011
7882011
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
JE Schlosburg, JL Blankman, JZ Long, DK Nomura, B Pan, SG Kinsey, ...
Nature neuroscience 13 (9), 1113-1119, 2010
7082010
Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function
M Valdearcos, MM Robblee, DI Benjamin, DK Nomura, AW Xu, ...
Cell reports 9 (6), 2124-2138, 2014
6162014
DGAT1-dependent lipid droplet biogenesis protects mitochondrial function during starvation-induced autophagy
TB Nguyen, SM Louie, JR Daniele, Q Tran, A Dillin, R Zoncu, DK Nomura, ...
Developmental cell 42 (1), 9-21. e5, 2017
5362017
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
R Camarda, AY Zhou, RA Kohnz, S Balakrishnan, C Mahieu, B Anderton, ...
Nature medicine 22 (4), 427-432, 2016
5282016
Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ...
Science 355 (6331), 1306-1311, 2017
5162017
Advances in covalent drug discovery
L Boike, NJ Henning, DK Nomura
Nature Reviews Drug Discovery 21 (12), 881-898, 2022
4492022
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo
JZ Long, DK Nomura, RE Vann, DM Walentiny, L Booker, X Jin, ...
Proceedings of the National Academy of Sciences 106 (48), 20270-20275, 2009
4492009
Activity-based protein profiling for biochemical pathway discovery in cancer
DK Nomura, MM Dix, BF Cravatt
Nature Reviews Cancer 10 (9), 630-638, 2010
3932010
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
JN Spradlin, X Hu, CC Ward, SM Brittain, MD Jones, L Ou, M To, ...
Nature chemical biology 15 (7), 747-755, 2019
3672019
Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism
JZ Long, DK Nomura, BF Cravatt
Chemistry & biology 16 (7), 744-753, 2009
3352009
A proximity labeling strategy provides insights into the composition and dynamics of lipid droplet proteomes
K Bersuker, CWH Peterson, M To, SJ Sahl, V Savikhin, EA Grossman, ...
Developmental cell 44 (1), 97-112. e7, 2018
3232018
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism
J Lee, AE Yesilkanal, JP Wynne, C Frankenberger, J Liu, J Yan, M Elbaz, ...
Nature 568 (7751), 254-258, 2019
3092019
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer
MJ Watt, AK Clark, LA Selth, VR Haynes, N Lister, R Rebello, LH Porter, ...
Science translational medicine 11 (478), eaau5758, 2019
3032019
Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer
DK Nomura, DP Lombardi, JW Chang, S Niessen, AM Ward, JZ Long, ...
Chemistry & biology 18 (7), 846-856, 2011
2992011
ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C
CY Lim, OB Davis, HR Shin, J Zhang, CA Berdan, X Jiang, JL Counihan, ...
Nature cell biology 21 (10), 1206-1218, 2019
2782019
Covalent ligand screening uncovers a RNF4 E3 ligase recruiter for targeted protein degradation applications
CC Ward, JI Kleinman, SM Brittain, PS Lee, CYS Chung, K Kim, Y Petri, ...
ACS chemical biology 14 (11), 2430-2440, 2019
2782019
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