Aryl hydrocarbon receptor signaling prevents activation of hepatic stellate cells and liver fibrogenesis in mice J Yan, HC Tung, S Li, Y Niu, WG Garbacz, P Lu, Y Bi, Y Li, J He, M Xu, ... Gastroenterology 157 (3), 793-806. e14, 2019 | 97 | 2019 |
The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1 Y Xi, Y Li, P Xu, S Li, Z Liu, H Tung, X Cai, J Wang, H Huang, M Wang, ... Science Advances 7 (36), eabg9241, 2021 | 43 | 2021 |
The Beneficial Effects of P2X7 Antagonism in Rats with Bile Duct Ligation-induced Cirrhosis HC Tung, FY Lee, SS Wang, MH Tsai, JY Lee, TI Huo, HC Huang, ... PLoS One 10 (5), e0124654, 2015 | 42 | 2015 |
Resveratrol exhibits differential protective effects on fast‐and slow‐twitch muscles in streptozotocin‐induced diabetic rats CC Chang, MH Yang, HC Tung, CY Chang, YL Tsai, JP Huang, TH Yen, ... Journal of diabetes 6 (1), 60-67, 2014 | 31 | 2014 |
Inhibition of p53 sulfoconjugation prevents oxidative hepatotoxicity and acute liver failure P Xu, Y Xi, P Wang, Z Luka, M Xu, HC Tung, J Wang, S Ren, D Feng, ... Gastroenterology 162 (4), 1226-1241, 2022 | 26 | 2022 |
Inhibition of estrogen sulfotransferase (SULT1E1/EST) ameliorates ischemic acute kidney injury in mice ACS Barbosa, D Zhou, Y Xie, YJ Choi, HC Tung, X Chen, M Xu, RB Gibbs, ... Journal of the American Society of Nephrology 31 (7), 1496-1508, 2020 | 18 | 2020 |
Homocysteine deteriorates intrahepatic derangement and portal-systemic collaterals in cirrhotic rats HC Tung, SJ Hsu, MH Tsai, TY Lin, IF Hsin, TI Huo, FY Lee, HC Huang, ... Clinical Science 131 (1), 69-86, 2017 | 12 | 2017 |
An unexpected role of cholesterol sulfotransferase and its regulation in sensitizing mice to acetaminophen-induced liver injury Y An, P Wang, P Xu, HC Tung, Y Xie, L Kirisci, M Xu, S Ren, X Tian, X Ma, ... Molecular Pharmacology 95 (6), 597-605, 2019 | 9 | 2019 |
Activation of Liver X Receptor α Sensitizes Mice to T‐Cell Mediated Hepatitis L Gao, B Li, J Wang, D Shen, M Yang, R Sun, HC Tung, M Xu, S Ren, ... Hepatology Communications 4 (11), 1664-1679, 2020 | 7 | 2020 |
Cell Type–Specific Roles of CD38 in the Interactions of Isoniazid with NAD+ in the Liver J Zhu, J Lu, HC Tung, K Liu, J Li, DM Grant, W Xie, X Ma Drug Metabolism and Disposition 48 (12), 1372-1379, 2020 | 4 | 2020 |
Hepatocyte estrogen sulfotransferase inhibition protects female mice from concanavalin A–induced T cell–mediated hepatitis independent of estrogens J Wang, Z Zhang, J Guan, HC Tung, J Xie, H Huang, Y Chen, M Xu, ... Journal of Biological Chemistry 299 (3), 2023 | 3 | 2023 |
The de-sulfinylation enzyme sulfiredoxin-1 attenuates hepatic stellate cell activation and liver fibrosis by modulating the PTPN12-NLRP3 axis JW Kim, HC Tung, M Ke, P Xu, X Cai, Y Xi, M Xu, S Ren, Y Huang, ... Hepatology, 10.1097, 2024 | 1 | 2024 |
Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose HC Tung, JW Kim, J Zhu, S Li, J Yan, Q Liu, I Koo, SA Koshkin, F Hao, ... Science Translational Medicine 16 (766), eadk8446, 2024 | | 2024 |
The Role of Cytochrome P450 1b1 in Liver Fibrosis and Trehalose Metabolsim HC Tung University of Pittsburgh, 2022 | | 2022 |
Inhibition of Cytochrome P450 1B1 Prevents Hepatic Stellate Cell Activation and Liver Fibrosis HC Tung, J Yan, S Li, G Zhong, M Xu, J Zhu, F Gonzalez, X Ma, ... The FASEB Journal 35, 2021 | | 2021 |
P179-Cell-type specific metabolism of isoniazid in the liver J Zhu, J Lu, HC Tung, W Xie, X Ma Drug Metabolism and Pharmacokinetics 35 (1), S77, 2020 | | 2020 |
The Beneficial Effects of P2X7 Antagonism on Hepatic Fibrogenesis and Portal-Systemic Collaterals in Rats with Bile Duct Ligation: 2006 HC Tung, TI Huo, FY Lee, HC Huang Hepatology 60, 1177A, 2014 | | 2014 |
The desulfinylation enzyme sulfiredoxin-1 attenuates HSC activation and liver fibrosis by modulating the PTPN12-NLRP3 axis JW Kim, HC Tung, M Ke, P Xu, X Cai, Y Xi, M Xu, S Ren, Y Huang, ... Hepatology, 10.1097, 0 | | |