| Nuclear m6A reader YTHDC1 regulates mRNA splicing W Xiao, S Adhikari, U Dahal, YS Chen, YJ Hao, BF Sun, HY Sun, A Li, ... Molecular cell 61 (4), 507-519, 2016 | 1892 | 2016 |
| Benchmarking sets for molecular docking N Huang, BK Shoichet, JJ Irwin Journal of medicinal chemistry 49 (23), 6789-6801, 2006 | 1594 | 2006 |
| 5-methylcytosine promotes mRNA export—NSUN2 as the methyltransferase and ALYREF as an m5C reader X Yang, Y Yang, BF Sun, YS Chen, JW Xu, WY Lai, A Li, X Wang, ... Cell research 27 (5), 606-625, 2017 | 876 | 2017 |
| Determination of electrostatic parameters for a polarizable force field based on the classical Drude oscillator VM Anisimov, G Lamoureux, IV Vorobyov, N Huang, B Roux, ... Journal of chemical theory and computation 1 (1), 153-168, 2005 | 340 | 2005 |
| Automated docking screens: a feasibility study JJ Irwin, BK Shoichet, MM Mysinger, N Huang, F Colizzi, P Wassam, ... Journal of medicinal chemistry 52 (18), 5712-5720, 2009 | 321 | 2009 |
| Molecular mechanics methods for predicting protein–ligand binding N Huang, C Kalyanaraman, K Bernacki, MP Jacobson Physical Chemistry Chemical Physics 8 (44), 5166-5177, 2006 | 295 | 2006 |
| Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1 S Peng, W Xiao, D Ju, B Sun, N Hou, Q Liu, Y Wang, H Zhao, C Gao, ... Science Translational Medicine 11 (488), eaau7116, 2019 | 258 | 2019 |
| Consideration of molecular weight during compound selection in virtual target-based database screening Y Pan, N Huang, S Cho, AD Mackerell Journal of chemical information and computer sciences 43 (1), 267-272, 2003 | 225 | 2003 |
| Physics-based scoring of protein− ligand complexes: Enrichment of known inhibitors in large-scale virtual screening N Huang, C Kalyanaraman, JJ Irwin, MP Jacobson Journal of Chemical Information and Modeling 46 (1), 243-253, 2006 | 207 | 2006 |
| Protein-facilitated base flipping in DNA by cytosine-5-methyltransferase N Huang, NK Banavali, AD MacKerell Jr Proceedings of the National Academy of Sciences 100 (1), 68-73, 2003 | 166 | 2003 |
| Molecular determinants of enterovirus 71 viral entry: cleft around GLN-172 on VP1 protein interacts with variable region on scavenge receptor B 2 P Chen, Z Song, Y Qi, X Feng, N Xu, Y Sun, X Wu, X Yao, Q Mao, X Li, ... Journal of Biological Chemistry 287 (9), 6406-6420, 2012 | 165 | 2012 |
| Exploiting ordered waters in molecular docking N Huang, BK Shoichet Journal of medicinal chemistry 51 (16), 4862-4865, 2008 | 157 | 2008 |
| Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants P Han, C Su, Y Zhang, C Bai, A Zheng, C Qiao, Q Wang, S Niu, Q Chen, ... Nature communications 12 (1), 6103, 2021 | 155 | 2021 |
| FAD-dependent enzyme-catalysed intermolecular [4+ 2] cycloaddition in natural product biosynthesis L Gao, C Su, X Du, R Wang, S Chen, Y Zhou, C Liu, X Liu, R Tian, ... Nature Chemistry 12 (7), 620-628, 2020 | 136 | 2020 |
| Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA. 2 and BA. 1.1 L Li, H Liao, Y Meng, W Li, P Han, K Liu, Q Wang, D Li, Y Zhang, L Wang, ... Cell 185 (16), 2952-2960. e10, 2022 | 132 | 2022 |
| Predicting or pretending: artificial intelligence for protein-ligand interactions lack of sufficiently large and unbiased datasets J Yang, C Shen, N Huang Frontiers in pharmacology 11, 69, 2020 | 117 | 2020 |
| Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine T Dong, C Li, X Wang, L Dian, X Zhang, L Li, S Chen, R Cao, L Li, ... Nature communications 6 (1), 6522, 2015 | 117 | 2015 |
| A Review of FoxO1-Regulated Metabolic Diseases and Related Drug Discoveries S Peng, W Li, N Hou, N Huang Cells 9 (1), 184, 2020 | 112 | 2020 |
| Fto deficiency reduces anxiety-and depression-like behaviors in mice via alterations in gut microbiota L Sun, L Ma, H Zhang, Y Cao, C Wang, N Hou, N Huang, KM von Deneen, ... Theranostics 9 (3), 721, 2019 | 107 | 2019 |
| A survey of the role of nitrile groups in protein–ligand interactions Y Wang, Y Du, N Huang Future medicinal chemistry 10 (23), 2713-2728, 2018 | 105 | 2018 |
