Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) X Xu, KL Poulsen, L Wu, S Liu, T Miyata, Q Song, Q Wei, C Zhao, C Lin, ... Signal transduction and targeted therapy 7 (1), 287, 2022 | 209 | 2022 |
A virus-induced conformational switch of STAT1-STAT2 dimers boosts antiviral defenses Y Wang, Q Song, W Huang, Y Lin, X Wang, C Wang, B Willard, C Zhao, ... Cell Research 31 (2), 206-218, 2021 | 48 | 2021 |
Axl inhibitor R428 induces apoptosis of cancer cells by blocking lysosomal acidification and recycling independent of Axl inhibition F Chen, Q Song, Q Yu American Journal of Cancer Research 8 (8), 1466, 2018 | 44 | 2018 |
Cucurbitacin I inhibits STAT3, but enhances STAT1 signaling in human cancer cells in vitro through disrupting actin filaments H Guo, S Kuang, Q Song, M Liu, X Sun, Q Yu Acta Pharmacologica Sinica 39 (3), 425-437, 2018 | 40 | 2018 |
The phagocytic receptors of β-glucan Y Zhang, X Liu, J Zhao, J Wang, Q Song, C Zhao International journal of biological macromolecules 205, 430-441, 2022 | 38 | 2022 |
A β-1, 3/1, 6-glucan from Durvillaea Antarctica inhibits tumor progression in vivo as an immune stimulator F Su, Q Song, C Zhang, X Xu, M Li, D Yao, L Wu, X Qu, H Guan, G Yu, ... Carbohydrate polymers 222, 114993, 2019 | 35 | 2019 |
Small-molecule inhibitors targeting the canonical WNT signaling pathway for the treatment of cancer Z Liu, P Wang, EA Wold, Q Song, C Zhao, C Wang, J Zhou Journal of medicinal chemistry 64 (8), 4257-4288, 2021 | 32 | 2021 |
E2F is required for STAT3-mediated upregulation of cyclin B1 and Cdc2 expressions and contributes to G2–M phase transition J Sun, Y Du, Q Song, J Nan, P Guan, J Guo, X Wang, J Yang, C Zhao Acta Biochimica et Biophysica Sinica 51 (3), 313-322, 2019 | 32 | 2019 |
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells Q Song, X Sun, H Guo, Q Yu Oncotarget 8 (3), 5003, 2016 | 22 | 2016 |
Type I interferon signaling facilitates resolution of acute liver injury by priming macrophage polarization Q Song, S Datta, X Liang, X Xu, P Pavicic, X Zhang, Y Zhao, S Liu, J Zhao, ... Cellular & molecular immunology 20 (2), 143-157, 2023 | 19 | 2023 |
Unfolded protein response differentially regulates TLR4-induced cytokine expression in distinct macrophage populations L Zhang, PG Pavicic Jr, S Datta, Q Song, X Xu, W Wei, F Su, PA Rayman, ... Frontiers in Immunology 10, 1390, 2019 | 17 | 2019 |
Zelnorm, an agonist of 5-Hydroxytryptamine 4-receptor, acts as a potential antitumor drug by targeting JAK/STAT3 signaling L Zhang, Q Song, X Zhang, L Li, X Xu, X Xu, X Li, Z Wang, Y Lin, X Li, M Li, ... Investigational New Drugs 38, 311-320, 2020 | 15 | 2020 |
Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment W Wei, Y Zhang, Q Song, Q Zhang, X Zhang, X Liu, Z Wu, X Xu, Y Xu, ... Cellular and Molecular Life Sciences 79 (8), 403, 2022 | 14 | 2022 |
Inhibition of Histone H3 Lysine-27 Demethylase Activity Relieves Rheumatoid Arthritis Symptoms via Repression of IL6 Transcription in Macrophages Z Zhao, Y Zhang, D Gao, Y Zhang, W Han, X Xu, Q Song, C Zhao, J Yang Frontiers in Immunology 13, 818070, 2022 | 12 | 2022 |
A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization W Tian, L Qin, Q Song, L He, M Ai, Y Jin, Z Zhou, S You, Y Long, Q Yu PLoS One 5 (5), e10499, 2010 | 12 | 2010 |
Receptor Tyrosine Kinase Phosphorylation Pattern–Based Multidrug Combination Is an Effective Approach for Personalized Cancer Treatment X Sun, Q Song, L He, L Yan, J Liu, Q Zhang, Q Yu Molecular Cancer Therapeutics 15 (10), 2508-2520, 2016 | 11 | 2016 |
Scaffold compound L971 exhibits anti‐inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways M Li, Y Yan, X Zhang, Y Zhang, X Xu, L Zhang, L Lu, J Wang, Y Zhang, ... Journal of Cellular and Molecular Medicine 25 (13), 6333-6347, 2021 | 9 | 2021 |
Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3 J Sun, Y Du, X Zhang, Z Wang, Y Lin, Q Song, X Wang, J Guo, S Li, J Nan, ... Investigational New Drugs 38, 1003-1011, 2020 | 9 | 2020 |
STX5 inhibits hepatocellular carcinoma adhesion and promotes metastasis by regulating the PI3K/mTOR pathway B Zhang, Z Zhao, Y Wang, T Guo, M He, G Guan, P Peng, J Cai, B Zhang, ... Journal of Clinical and Translational Hepatology 11 (3), 572, 2023 | 7 | 2023 |
The culture dish surface influences the phenotype and dissociation strategy in distinct mouse macrophage populations Q Song, Y Zhang, M Zhou, Y Xu, Q Zhang, L Wu, S Liu, M Zhang, L Zhang, ... Frontiers in Immunology 13, 920232, 2022 | 6 | 2022 |