Comprehensive functional genomic resource and integrative model for the human brain D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ... Science 362 (6420), eaat8464, 2018 | 929 | 2018 |
Systematic immunotherapy target discovery using genome-scale in vivo CRISPR screens in CD8 T cells MB Dong, G Wang, RD Chow, L Ye, L Zhu, X Dai, JJ Park, HR Kim, ... Cell 178 (5), 1189-1204. e23, 2019 | 277 | 2019 |
Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA S Yuan, L Peng, JJ Park, Y Hu, SC Devarkar, MB Dong, Q Shen, S Wu, ... Molecular cell 80 (6), 1055-1066. e6, 2020 | 185 | 2020 |
In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma L Ye, JJ Park, MB Dong, Q Yang, RD Chow, L Peng, Y Du, J Guo, X Dai, ... Nature biotechnology 37 (11), 1302-1313, 2019 | 169 | 2019 |
exceRpt: a comprehensive analytic platform for extracellular RNA profiling J Rozowsky, RR Kitchen, JJ Park, TR Galeev, J Diao, J Warrell, ... Cell systems 8 (4), 352-357. e3, 2019 | 156 | 2019 |
One-step generation of modular CAR-T cells with AAV–Cpf1 X Dai, JJ Park, Y Du, HR Kim, G Wang, Y Errami, S Chen Nature Methods 16 (3), 247-254, 2019 | 154 | 2019 |
Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase B Rada, MA Jendrysik, L Pang, CP Hayes, D Yoo, JJ Park, SM Moskowitz, ... PloS one 8 (1), e54205, 2013 | 149 | 2013 |
A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy L Ye, JJ Park, L Peng, Q Yang, RD Chow, MB Dong, SZ Lam, J Guo, ... Cell metabolism 34 (4), 595-614. e14, 2022 | 125 | 2022 |
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity G Wang, RD Chow, Z Bai, L Zhu, Y Errami, X Dai, MB Dong, L Ye, ... Nature Immunology 20 (11), 1494-1505, 2019 | 109 | 2019 |
NLRP3 inflammasome activation and interleukin-1β release in macrophages require calcium but are independent of calcium-activated NADPH oxidases B Rada, JJ Park, P Sil, M Geiszt, TL Leto Inflammation Research 63, 821-830, 2014 | 67 | 2014 |
Histamine stimulates hydrogen peroxide production by bronchial epithelial cells via histamine H1 receptor and dual oxidase B Rada, HE Boudreau, JJ Park, TL Leto American journal of respiratory cell and molecular biology 50 (1), 125-134, 2014 | 54 | 2014 |
Growth characterization of electron-beam-induced silver deposition from liquid precursor LE Ocola, A Joshi-Imre, C Kessel, B Chen, J Park, D Gosztola, R Divan Journal of Vacuum Science & Technology B 30 (6), 2012 | 35 | 2012 |
Massively parallel knock-in engineering of human T cells X Dai, JJ Park, Y Du, Z Na, SZ Lam, RD Chow, PA Renauer, J Gu, S Xin, ... Nature Biotechnology 41 (9), 1239-1255, 2023 | 33 | 2023 |
Convergent identification and interrogation of tumor-intrinsic factors that modulate cancer immunity in vivo A Codina, PA Renauer, G Wang, RD Chow, JJ Park, H Ye, K Zhang, ... Cell systems 8 (2), 136-151. e7, 2019 | 21 | 2019 |
Machine learning identifies T cell receptor repertoire signatures associated with COVID-19 severity JJ Park, KAV Lee, SZ Lam, KS Moon, Z Fang, S Chen Communications Biology 6 (1), 76, 2023 | 20 | 2023 |
Histone modifications affect differential regulation of TGFβ-induced NADPH oxidase 4 (NOX4) by wild-type and mutant p53 HE Boudreau, WF Ma, A Korzeniowska, JJ Park, MA Bhagwat, TL Leto Oncotarget 8 (27), 44379, 2017 | 20 | 2017 |
Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species L Peng, Z Fang, PA Renauer, A McNamara, JJ Park, Q Lin, X Zhou, ... Cell Reports 40 (5), 2022 | 18 | 2022 |
Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2 L Peng, PA Renauer, A Ökten, Z Fang, JJ Park, X Zhou, Q Lin, MB Dong, ... Cell Reports Medicine 3 (5), 2022 | 18 | 2022 |
Immunogenetic metabolomics reveals key enzymes that modulate CAR T-cell metabolism and function P Renauer, JJ Park, M Bai, A Acosta, WH Lee, GH Lin, Y Zhang, X Dai, ... Cancer immunology research 11 (8), 1068-1084, 2023 | 11 | 2023 |
Treatment of cutaneous lupus with topical ruxolitinib cream JJ Park, AJ Little, MD Vesely JAAD Case Reports 28, 133-135, 2022 | 11 | 2022 |