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Besim Ogretmen
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
112952021
Biologically active sphingolipids in cancer pathogenesis and treatment
B Ogretmen, YA Hannun
Nature Reviews Cancer 4 (8), 604-616, 2004
15362004
Sphingolipid metabolism in cancer signalling and therapy
B Ogretmen
Nature Reviews Cancer 18 (1), 33-50, 2018
10702018
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
RD Sentelle, CE Senkal, W Jiang, S Ponnusamy, S Gencer, SP Selvam, ...
Nature Chemical Biology 8 (10), 831-838, 2012
5742012
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells
CE Chalfant, K Rathman, RL Pinkerman, RE Wood, LM Obeid, ...
Journal of Biological Chemistry 277 (15), 12587-12595, 2002
4152002
Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance
S Ponnusamy, M Meyers-Needham, CE Senkal, SA Saddoughi, ...
Future oncology 6 (10), 1603-1624, 2010
3842010
Roles of bioactive sphingolipids in cancer biology and therapeutics
SA Saddoughi, P Song, B Ogretmen
Lipids in Health and Disease, 413-440, 2008
3152008
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
SA Saddoughi, S Gencer, YK Peterson, KE Ward, A Mukhopadhyay, ...
EMBO molecular medicine 5 (1), 105-121, 2013
3142013
Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways
CE Senkal, S Ponnusamy, J Bielawski, YA Hannun, B Ogretmen
The FASEB Journal 24 (1), 296, 2010
2892010
Defects in cell growth regulation by C18: 0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas
S Koybasi, CE Senkal, K Sundararaj, S Spassieva, J Bielawski, W Osta, ...
Journal of Biological Chemistry 279 (43), 44311-44319, 2004
2772004
Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells
Y Baran, A Salas, CE Senkal, U Gunduz, J Bielawski, LM Obeid, ...
Journal of Biological Chemistry 282 (15), 10922-10934, 2007
2722007
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells
P Neviani, JG Harb, JJ Oaks, R Santhanam, CJ Walker, JJ Ellis, ...
The Journal of clinical investigation 123 (10), 4144-4157, 2013
2682013
Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
A Mukhopadhyay, SA Saddoughi, P Song, I Sultan, S Ponnusamy, ...
The FASEB Journal 23 (3), 751, 2009
2652009
CD38-NAD+ axis regulates immunotherapeutic anti-tumor T cell response
S Chatterjee, A Daenthanasanmak, P Chakraborty, MW Wyatt, P Dhar, ...
Cell metabolism 27 (1), 85-100. e8, 2018
2552018
Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue
KR Johnson, KY Johnson, HG Crellin, B Ogretmen, AM Boylan, RA Harley, ...
Journal of Histochemistry & Cytochemistry 53 (9), 1159-1166, 2005
2522005
Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line
B Ogretmen, BJ Pettus, MJ Rossi, R Wood, J Usta, Z Szulc, A Bielawska, ...
Journal of Biological Chemistry 277 (15), 12960-12969, 2002
2492002
Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C18-ceramide in HNSCC tumors correlates …
S Karahatay, K Thomas, S Koybasi, CE Senkal, S ElOjeimy, X Liu, ...
Cancer letters 256 (1), 101-111, 2007
2312007
Diverse functions of ceramide in cancer cell death and proliferation
SA Saddoughi, B Ogretmen
Advances in cancer research 117, 37-58, 2013
2172013
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas
CE Senkal, S Ponnusamy, MJ Rossi, J Bialewski, D Sinha, JC Jiang, ...
Molecular cancer therapeutics 6 (2), 712-722, 2007
2032007
Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells
JM Kraveka, L Li, ZM Szulc, J Bielawski, B Ogretmen, YA Hannun, ...
Journal of Biological Chemistry 282 (23), 16718-16728, 2007
2002007
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