Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases E Beurel, SF Grieco, RS Jope Pharmacology & therapeutics 148, 114-131, 2015 | 1797 | 2015 |
The bidirectional relationship of depression and inflammation: double trouble E Beurel, M Toups, CB Nemeroff Neuron 107 (2), 234-256, 2020 | 1573 | 2020 |
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics RS Jope, CJ Yuskaitis, E Beurel Neurochemical research 32, 577-595, 2007 | 997 | 2007 |
The paradoxical pro-and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways E Beurel, RS Jope Progress in neurobiology 79 (4), 173-189, 2006 | 714 | 2006 |
Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3) E Beurel, SM Michalek, RS Jope Trends in immunology 31 (1), 24-31, 2010 | 470 | 2010 |
Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice E Beurel, L Song, RS Jope Molecular psychiatry 16 (11), 1068-1070, 2011 | 335 | 2011 |
Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain E Beurel, RS Jope Journal of neuroinflammation 6, 1-11, 2009 | 279 | 2009 |
Inflammatory T helper 17 cells promote depression-like behavior in mice E Beurel, LE Harrington, RS Jope Biological psychiatry 73 (7), 622-630, 2013 | 274 | 2013 |
Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances A Polter, E Beurel, S Yang, R Garner, L Song, CA Miller, JD Sweatt, ... Neuropsychopharmacology 35 (8), 1761-1774, 2010 | 274 | 2010 |
GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism MA Mines, CJ Yuskaitis, MK King, E Beurel, RS Jope PloS one 5 (3), e9706, 2010 | 248 | 2010 |
TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice Y Cheng, S Desse, A Martinez, RJ Worthen, RS Jope, E Beurel Brain, behavior, and immunity 69, 556-567, 2018 | 244 | 2018 |
Differential regulation of STAT family members by glycogen synthase kinase-3 E Beurel, RS Jope Journal of Biological Chemistry 283 (32), 21934-21944, 2008 | 212 | 2008 |
Defective inflammatory pathways in never-treated depressed patients are associated with poor treatment response SA Syed, E Beurel, DA Loewenstein, JA Lowell, WE Craighead, ... Neuron 99 (5), 914-924. e3, 2018 | 201 | 2018 |
Glycogen synthase kinase-3 inhibitors: rescuers of cognitive impairments MK King, M Pardo, Y Cheng, K Downey, RS Jope, E Beurel Pharmacology & therapeutics 141 (1), 1-12, 2014 | 200 | 2014 |
Th17 cells in depression E Beurel, JA Lowell Brain, behavior, and immunity 69, 28-34, 2018 | 187 | 2018 |
Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior Y Cheng, M Pardo, R de Souza Armini, A Martinez, H Mouhsine, ... Brain, behavior, and immunity 53, 207-222, 2016 | 181 | 2016 |
Stressed and inflamed, can GSK3 be blamed? RS Jope, Y Cheng, JA Lowell, RJ Worthen, YH Sitbon, E Beurel Trends in biochemical sciences 42 (3), 180-192, 2017 | 121 | 2017 |
Overexpression of insulin receptor substrate-2 in human and murine hepatocellular carcinoma M Boissan, E Beurel, D Wendum, C Rey, Y Lécluse, C Housset, ... The American journal of pathology 167 (3), 869-877, 2005 | 121 | 2005 |
Convergence of the mammalian target of rapamycin complex 1-and glycogen synthase kinase 3-β–signaling pathways regulates the innate inflammatory response H Wang, J Brown, Z Gu, CA Garcia, R Liang, P Alard, E Beurel, RS Jope, ... The Journal of Immunology 186 (9), 5217-5226, 2011 | 119 | 2011 |
Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells E Beurel, WI Yeh, SM Michalek, LE Harrington, RS Jope The Journal of Immunology 186 (3), 1391-1398, 2011 | 106 | 2011 |