Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery H Cho, T Uehara, TG Bernhardt Cell 159 (6), 1300-1311, 2014 | 736 | 2014 |
How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan) JT Park, T Uehara Microbiology and Molecular Biology Reviews 72 (2), 211-227, 2008 | 556 | 2008 |
SEDS proteins are a widespread family of bacterial cell wall polymerases AJ Meeske, EP Riley, WP Robins, T Uehara, JJ Mekalanos, D Kahne, ... Nature 537 (7622), 634-638, 2016 | 529 | 2016 |
Daughter cell separation is controlled by cytokinetic ring‐activated cell wall hydrolysis T Uehara, KR Parzych, T Dinh, TG Bernhardt The EMBO journal 29 (8), 1412-1422, 2010 | 391 | 2010 |
Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases C Paradis-Bleau, M Markovski, T Uehara, TJ Lupoli, S Walker, DE Kahne, ... Cell 143 (7), 1110-1120, 2010 | 367 | 2010 |
LytM-domain factors are required for daughter cell separation and rapid ampicillin-induced lysis in Escherichia coli T Uehara, T Dinh, TG Bernhardt Journal of bacteriology 191 (16), 5094-5107, 2009 | 268 | 2009 |
An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring DC Yang, NT Peters, KR Parzych, T Uehara, M Markovski, TG Bernhardt Proceedings of the National Academy of Sciences 108 (45), E1052-E1060, 2011 | 240 | 2011 |
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and … JC Hamrick, JD Docquier, T Uehara, CL Myers, DA Six, CL Chatwin, ... Antimicrobial Agents and Chemotherapy 64 (3), 10.1128/aac. 01963-19, 2020 | 179 | 2020 |
A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis C Morlot, T Uehara, KA Marquis, TG Bernhardt, DZ Rudner Genes & development 24 (4), 411-422, 2010 | 135 | 2010 |
More than just lysins: peptidoglycan hydrolases tailor the cell wall T Uehara, TG Bernhardt Current opinion in microbiology 14 (6), 698-703, 2011 | 132 | 2011 |
Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate T Uehara, K Suefuji, N Valbuena, B Meehan, M Donegan, JT Park Journal of bacteriology 187 (11), 3643-3649, 2005 | 127 | 2005 |
The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling T Uehara, JT Park Journal of bacteriology 186 (21), 7273-7279, 2004 | 120 | 2004 |
Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation T Uehara, JT Park Journal of bacteriology 190 (11), 3914-3922, 2008 | 117 | 2008 |
An anhydro-N-acetylmuramyl-L-alanine amidase with broad specificity tethered to the outer membrane of Escherichia coli T Uehara, JT Park Journal of bacteriology 189 (15), 5634-5641, 2007 | 116 | 2007 |
Structure–function analysis of the LytM domain of EnvC, an activator of cell wall remodelling at the Escherichia coli division site NT Peters, C Morlot, DC Yang, T Uehara, T Vernet, TG Bernhardt Molecular Microbiology 89 (4), 690-701, 2013 | 78 | 2013 |
MurQ etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall T Uehara, K Suefuji, T Jaeger, C Mayer, JT Park Journal of bacteriology 188 (4), 1660-1662, 2006 | 71 | 2006 |
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae–identification of LYS228 F Reck, A Bermingham, J Blais, V Capka, T Cariaga, A Casarez, R Colvin, ... Bioorganic & medicinal chemistry letters 28 (4), 748-755, 2018 | 63 | 2018 |
Identification of MpaA, an Amidase in Escherichia coli That Hydrolyzes the γ-d-Glutamyl-meso-Diaminopimelate Bond in Murein Peptides T Uehara, JT Park Journal of bacteriology 185 (2), 679-682, 2003 | 54 | 2003 |
Role of the murein precursor UDP-N-acetylmuramyl-l-Ala-γ-d-Glu-meso-diaminopimelic acid-d-Ala-d-Ala in repression of β-lactamase induction in cell division mutants T Uehara, JT Park Journal of bacteriology 184 (15), 4233-4239, 2002 | 50 | 2002 |
Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae CR Dean, DT Barkan, A Bermingham, J Blais, F Casey, A Casarez, ... Antimicrobial Agents and Chemotherapy 62 (10), 10.1128/aac. 01200-18, 2018 | 44 | 2018 |