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Sharon Muggeo
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Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity
S Bido, S Muggeo, L Massimino, MJ Marzi, SG Giannelli, E Melacini, ...
Nature communications 12 (1), 6237, 2021
1282021
Frataxin gene editing rescues Friedreich’s ataxia pathology in dorsal root ganglia organoid-derived sensory neurons
PG Mazzara, S Muggeo, M Luoni, L Massimino, M Zaghi, PTT Valverde, ...
Nature Communications 11 (1), 4178, 2020
672020
Targeted gene correction in osteopetrotic-induced pluripotent stem cells for the generation of functional osteoclasts
T Neri, S Muggeo, M Paulis, ME Caldana, L Crisafulli, D Strina, ...
Stem Cell Reports 5 (4), 558-568, 2015
262015
MicroRNA-127-3p controls murine hematopoietic stem cell maintenance by limiting differentiation
L Crisafulli, S Muggeo, P Uva, Y Wang, M Iwasaki, S Locatelli, A Anselmo, ...
haematologica 104 (9), 1744, 2019
172019
A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development
V Benedetti, F Banfi, M Zaghi, R Moll-Diaz, L Massimino, L Argelich, ...
Science advances 8 (31), eabn3986, 2022
152022
PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm
S Muggeo, L Crisafulli, P Uva, E Fontana, M Ubezio, E Morenghi, ...
Stem Cell Reports 16 (11), 2607-2616, 2021
122021
Author Correction: Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity
S Bido, S Muggeo, L Massimino, MJ Marzi, SG Giannelli, E Melacini, ...
Nature Communications 12, 2021
102021
Generation of an immunodeficient mouse model of tcirg1-deficient autosomal recessive osteopetrosis
E Palagano, S Muggeo, L Crisafulli, IL Tourkova, D Strina, S Mantero, ...
Bone Reports 12, 100242, 2020
92020
MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice
G Rossi, G Ordazzo, NN Vanni, V Castoldi, A Iannielli, D Di Silvestre, ...
Elife 12, e81779, 2023
82023
Chromosome transplantation: correction of the chronic granulomatous disease defect in mouse induced pluripotent stem cells
A Castelli, L Susani, C Menale, S Muggeo, E Caldana, D Strina, ...
Stem Cells 37 (7), 876-887, 2019
72019
Developmental instability of CA1 pyramidal cells in Dravet Syndrome
SP Jones, N O’Neill, S Muggeo, G Colasante, DM Kullmann, G Lignani
bioRxiv, 2022.09. 12.507264, 2022
62022
Microglia‑specific overexpression of alpha‑synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity. Nat Commun 12: 6237
S Bido, S Muggeo, L Massimino, MJ Marzi, SG Giannelli, E Melacini
52021
A human stem cell-derived neurosensory–epithelial circuitry on a chip to model herpes simplex virus reactivation
PG Mazzara, E Criscuolo, M Rasponi, L Massimino, S Muggeo, C Palma, ...
Biomedicines 10 (9), 2068, 2022
42022
Osteopetrose
A Schulz, U Kornak
Osteologie 27 (04), 222-228, 2018
32018
Microglia-specific IL-10 gene delivery inhibits neuroinflammation and neurodegeneration in a mouse model of Parkinson’s disease
S Bido, M Nannoni, S Muggeo, D Gambarè, G Ruffini, E Bellini, L Passeri, ...
Science Translational Medicine 16 (761), eadm8563, 2024
22024
Early developmental alterations of CA1 pyramidal cells in Dravet syndrome
SP Jones, N O'Neill, JC Carpenter, S Muggeo, G Colasante, ...
Neurobiology of Disease 201, 106688, 2024
2024
Microglia Behavioral Reprogramming Is Sufficient to Rescue Dopaminergic Neurons from alpha-Synuclein Accumulation-Mediated Cell Loss
S Bido, D Gambare, M Nannoni, S Muggeo, S Giannelli, E Melacini, ...
MOLECULAR THERAPY 29 (4), 270-270, 2021
2021
3073–PBX1 GENETIC ABLATION INHIBITS TUMOR GROWTH IN A MOUSE MODEL OF MYELOPROLIFERATIVE NEOPLASM
F Ficara, S Muggeo, L Crisafulli, P Uva, E Fontana, M Ubezio, F Colombo, ...
Experimental Hematology 88, S60-S61, 2020
2020
3072–MICRORNA-127-3P CONTROLS MURINE HEMATOPOIETIC STEM CELL MAINTENANCE BY LIMITING DIFFERENTIATION
F Ficara, L Crisafulli, S Muggeo, P Uva, Y Wang, M Iwasaki, S Locatelli, ...
Experimental Hematology 88, S60, 2020
2020
LACK OF MIR-127 DOWN-REGULATION IN THE TRANSITION FROM HEMATOPOIETIC STEM CELLS TO MULTI-POTENT PROGENITORS LEADS TO PANCYTOPENIA AND DEFECTIVE SELF-RENEWAL
L Crisafulli, S Muggeo, P Uva, L Susani, M Cleary, P Vezzoni, B Gentner, ...
HAEMATOLOGICA 101, 292-292, 2016
2016
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