| Drug discovery targeting bromodomain-containing protein 4 Z Liu, P Wang, H Chen, EA Wold, B Tian, AR Brasier, J Zhou Journal of medicinal chemistry 60 (11), 4533-4558, 2017 | 291 | 2017 |
| Direct activation of Bax protein for cancer therapy Z Liu, Y Ding, N Ye, C Wild, H Chen, J Zhou Medicinal research reviews 36 (2), 313-341, 2016 | 249 | 2016 |
| Discovery and development of natural product oridonin-inspired anticancer agents Y Ding, C Ding, N Ye, Z Liu, EA Wold, H Chen, C Wild, Q Shen, J Zhou European journal of medicinal chemistry 122, 102-117, 2016 | 179 | 2016 |
| Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV Q Niu, Z Liu, E Alamer, X Fan, H Chen, J Endsley, BB Gelman, B Tian, ... The Journal of clinical investigation 129 (8), 3361-3373, 2019 | 77 | 2019 |
| Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation Z Liu, B Tian, H Chen, P Wang, AR Brasier, J Zhou European journal of medicinal chemistry 151, 450-461, 2018 | 73 | 2018 |
| Discovery of orally bioavailable chromone derivatives as potent and selective BRD4 inhibitors: scaffold hopping, optimization, and pharmacological evaluation Z Liu, H Chen, P Wang, Y Li, EA Wold, PG Leonard, S Joseph, AR Brasier, ... Journal of medicinal chemistry 63 (10), 5242-5256, 2020 | 71 | 2020 |
| BH4 domain of Bcl-2 as a novel target for cancer therapy Z Liu, C Wild, Y Ding, N Ye, H Chen, EA Wold, J Zhou Drug discovery today 21 (6), 989-996, 2016 | 66 | 2016 |
| Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators W Mao, M Ning, Z Liu, Q Zhu, Y Leng, A Zhang Bioorganic & medicinal chemistry 20 (9), 2982-2991, 2012 | 63 | 2012 |
| Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling B Tian, K Hosoki, Z Liu, J Yang, Y Zhao, H Sun, J Zhou, E Rytting, ... Journal of Allergy and Clinical Immunology 143 (4), 1380-1394. e9, 2019 | 55 | 2019 |
| Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets P Wang, Z Liu, H Chen, N Ye, X Cheng, J Zhou Bioorganic & medicinal chemistry letters 27 (8), 1633-1639, 2017 | 55 | 2017 |
| Efficacy of novel highly specific bromodomain-containing protein 4 inhibitors in innate inflammation–driven airway remodeling B Tian, Z Liu, J Litvinov, R Maroto, M Jamaluddin, E Rytting, I Patrikeev, ... American journal of respiratory cell and molecular biology 60 (1), 68-83, 2019 | 49 | 2019 |
| Discovery of novel 2, 4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases Z Song, Y Yang, Z Liu, X Peng, J Guo, X Yang, K Wu, J Ai, J Ding, M Geng, ... Journal of medicinal chemistry 58 (1), 197-211, 2015 | 49 | 2015 |
| Structure–Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N′-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange … N Ye, Y Zhu, H Chen, Z Liu, FC Mei, C Wild, H Chen, X Cheng, J Zhou Journal of medicinal chemistry 58 (15), 6033-6047, 2015 | 48 | 2015 |
| Selective antagonists of the bronchiolar epithelial NF-κB-bromodomain-containing protein 4 pathway in viral-induced airway inflammation B Tian, Z Liu, J Yang, H Sun, Y Zhao, M Wakamiya, H Chen, E Rytting, ... Cell reports 23 (4), 1138-1151, 2018 | 46 | 2018 |
| Regio-and stereospecific synthesis of oridonin D-ring aziridinated analogues for the treatment of triple-negative breast cancer via mediated irreversible covalent warheads Y Ding, D Li, C Ding, P Wang, Z Liu, EA Wold, N Ye, H Chen, MA White, ... Journal of medicinal chemistry 61 (7), 2737-2752, 2018 | 38 | 2018 |
| Discovery, X-ray crystallography, and anti-inflammatory activity of bromodomain-containing protein 4 (BRD4) BD1 inhibitors targeting a distinct new binding site Z Liu, Y Li, H Chen, HT Lai, P Wang, SY Wu, EA Wold, PG Leonard, ... Journal of medicinal chemistry 65 (3), 2388-2408, 2022 | 36 | 2022 |
| Global trends and regional differences in the burden of anxiety disorders and major depressive disorder attributed to bullying victimisation in 204 countries and territories … C Hong, Z Liu, L Gao, Y Jin, J Shi, R Liang, M Maimaitiming, X Ning, ... Epidemiology and psychiatric sciences 31, e85, 2022 | 35 | 2022 |
| Functional modulation of voltage-gated sodium channels by a FGF14-based peptidomimetic SR Ali, Z Liu, MN Nenov, O Folorunso, A Singh, F Scala, H Chen, ... ACS chemical neuroscience 9 (5), 976-987, 2018 | 35 | 2018 |
| Novel 2, 4-diarylaminopyrimidine analogues (DAAPalogues) showing potent c-Met/ALK multikinase inhibitory activities Z Liu, J Ai, X Peng, Z Song, K Wu, J Zhang, Q Yao, Y Chen, Y Ji, Y Yang, ... ACS Medicinal Chemistry Letters 5 (4), 304-308, 2014 | 35 | 2014 |
| Small-molecule inhibitors targeting the canonical WNT signaling pathway for the treatment of cancer Z Liu, P Wang, EA Wold, Q Song, C Zhao, C Wang, J Zhou Journal of medicinal chemistry 64 (8), 4257-4288, 2021 | 32 | 2021 |
Na YePostdoc, University of Texas Medical BranchVerified email at utmb.edu