Vitamin A-retinoic acid signaling regulates hematopoietic stem cell dormancy N Cabezas-Wallscheid, F Buettner, P Sommerkamp, D Klimmeck, L Ladel, ... Cell 169 (5), 807-823. e19, 2017 | 469 | 2017 |
A novel persulfide detection method reveals protein persulfide-and polysulfide-reducing functions of thioredoxin and glutathione systems É Dóka, I Pader, A Bíró, K Johansson, Q Cheng, K Ballagó, JR Prigge, ... Science advances 2 (1), e1500968, 2016 | 318 | 2016 |
Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes B Morgan, K Van Laer, TNE Owusu, D Ezeriņa, D Pastor-Flores, ... Nature chemical biology 12 (6), 437-443, 2016 | 238 | 2016 |
AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases JM Arencibia, D Pastor-Flores, AF Bauer, JO Schulze, RM Biondi Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1302-1321, 2013 | 232 | 2013 |
Real-time monitoring of peroxiredoxin oligomerization dynamics in living cells D Pastor-Flores, D Talwar, B Pedre, TP Dick Proceedings of the National Academy of Sciences 117 (28), 16313-16323, 2020 | 47 | 2020 |
Glucose Acutely Reduces Cytosolic and Mitochondrial H2O2 in Rat Pancreatic Beta Cells JP Deglasse, LP Roma, D Pastor-Flores, P Gilon, TP Dick, JC Jonas Antioxidants & redox signaling 30 (3), 297-313, 2019 | 30 | 2019 |
A click chemistry approach identifies target proteins of xanthohumol L Brodziak‐Jarosz, Y Fujikawa, D Pastor‐Flores, S Kasikci, P Jirásek, ... Molecular nutrition & food research 60 (4), 737-748, 2016 | 24 | 2016 |
An allosteric inhibitor scaffold targeting the PIF-pocket of atypical protein kinase C isoforms JM Arencibia, W Fröhner, M Krupa, D Pastor-Flores, P Merker, ... ACS Chemical Biology 12 (2), 564-573, 2017 | 22 | 2017 |
PIF-pocket as a target for C. albicans Pkh selective inhibitors D Pastor-Flores, JO Schulze, A Bahí, R Giacometti, J Ferrer-Dalmau, ... ACS chemical biology 8 (10), 2283-2292, 2013 | 18 | 2013 |
Lipid regulators of Pkh2 in Candida albicans, the protein kinase ortholog of mammalian PDK1 D Pastor-Flores, JO Schulze, A Bahí, E Süß, A Casamayor, RM Biondi Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 11 | 2016 |
Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein M Sacerdoti, LZF Gross, AM Riley, K Zehnder, A Ghode, S Klinke, ... Science signaling 16 (789), eadd3184, 2023 | 9 | 2023 |
Monitoring yeast mitochondria with peroxiredoxin-based redox probes: the influence of oxygen and glucose availability D Pastor-Flores, K Becker, TP Dick Interface Focus 7 (2), 20160143, 2017 | 6 | 2017 |
Depletion of yeast PDK1 orthologs triggers a stress-like transcriptional response D Pastor-Flores, J Ferrer-Dalmau, A Bahí, M Boleda, RM Biondi, ... BMC genomics 16, 1-21, 2015 | 3 | 2015 |
Fungal extract screening reveals malformin C to preferentially kill glioblastoma stem-like cells via concerted induction of proteotoxic stress and autophagic flux blockade EL Phillips, S van Enk, S Kildgaard, S Schlue, M Göttmann, V Jennings, ... Cancer Research 84 (6_Supplement), 655-655, 2024 | | 2024 |
Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy J Samarin, H Nuskova, P Fabrowski, M Malz, E Amtmann, MJ Taeubert, ... bioRxiv, 2024.11. 06.621846, 2024 | | 2024 |
Malformin C preferentially kills glioblastoma stem‐like cells via concerted induction of proteotoxic stress and autophagic flux blockade E Phillips, S van Enk, S Kildgaard, S Schlue, M Göttmann, V Jennings, ... Molecular oncology, 2024 | | 2024 |
Characterizing A Novel Fluorescent Biosensor Based On Human Peroxiredoxin 3 And A Redox Sensitive GFP G Cardozo, M Hugo, D Pastor-Flores, R Radi, AM Reyes, M Trujillo Free Radical Biology and Medicine 208, S116, 2023 | | 2023 |
PRDX2-and PRDX3-rsGFP2 fusions: response to relevant oxidants and redox sensors during hypoxia and reoxygenation inside living cells M Hugo, C Choya-Foces, D Pastor-Flores, A Martínez-Ruiz Free Radical Biology and Medicine 165, 27, 2021 | | 2021 |
Exit from HSC dormancy by a continuous upregulation of metabolism is controlled via vitamin A/retinoic acid N Cabezas-Wallscheid, F Buettner, D Klimmeck, P Sommerkamp, ... Experimental Hematology 44 (9), S54, 2016 | | 2016 |
Genetic and chemical biology approaches for the characterization of the yeast PDK1 orthologs in Saccharomyces cerevisiae and Candida albicans D Pastor-Flores Universitätsbibliothek Johann Christian Senckenberg, 2013 | | 2013 |