Generalized extracellular molecule sensor platform for programming cellular behavior L Scheller, T Strittmatter, D Fuchs, D Bojar, M Fussenegger Nature chemical biology 14 (7), 723-729, 2018 | 156 | 2018 |
Bottom-up de novo design of functional proteins with complex structural features C Yang, F Sesterhenn, J Bonet, EA van Aalen, L Scheller, LA Abriata, ... Nature Chemical Biology 17 (4), 492-500, 2021 | 97 | 2021 |
Caffeine-inducible gene switches controlling experimental diabetes D Bojar, L Scheller, GCE Hamri, M Xie, M Fussenegger Nature communications 9 (1), 2318, 2018 | 84 | 2018 |
A modular degron library for synthetic circuits in mammalian cells H Chassin, M Müller, M Tigges, L Scheller, M Lang, M Fussenegger Nature communications 10 (1), 2013, 2019 | 68 | 2019 |
Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation R Kojima, L Scheller, M Fussenegger Nature chemical biology 14 (1), 42-49, 2018 | 51 | 2018 |
Rewiring of endogenous signaling pathways to genomic targets for therapeutic cell reprogramming K Krawczyk, L Scheller, H Kim, M Fussenegger Nature communications 11 (1), 608, 2020 | 44 | 2020 |
From synthetic biology to human therapy: engineered mammalian cells L Scheller, M Fussenegger Current Opinion in Biotechnology 58, 108-116, 2019 | 42 | 2019 |
Phosphoregulated orthogonal signal transduction in mammalian cells L Scheller, M Schmollack, A Bertschi, M Mansouri, P Saxena, ... Nature communications 11 (1), 3085, 2020 | 35 | 2020 |
A rational blueprint for the design of chemically-controlled protein switches S Shui, P Gainza, L Scheller, C Yang, Y Kurumida, S Rosset, S Georgeon, ... Nature Communications 12 (1), 5754, 2021 | 31 | 2021 |
Programmable DARPin-based receptors for the detection of thrombotic markers T Strittmatter, Y Wang, A Bertschi, L Scheller, PC Freitag, PG Ray, ... Nature chemical biology 18 (10), 1125-1134, 2022 | 17 | 2022 |
Calcium‐Mediated Liposome Fusion to Engineer Giant Lipid Vesicles with Cytosolic Proteins and Reconstituted Mammalian Proteins YRF Schmid, L Scheller, S Buchmann, PS Dittrich Advanced biosystems 4 (11), 2000153, 2020 | 15 | 2020 |
Rational design of chemically controlled antibodies and protein therapeutics A Marchand, L Bonati, S Shui, L Scheller, P Gainza, S Rosset, ... ACS Chemical Biology 18 (6), 1259-1265, 2023 | 11 | 2023 |
Protein-based bandpass filters for controlling cellular signaling with chemical inputs S Shui, L Scheller, BE Correia Nature Chemical Biology 20 (5), 586-593, 2024 | 10* | 2024 |
Genetically encoded betaxanthin-based small-molecular fluorescent reporter for mammalian cells P Stücheli, S Sieber, DW Fuchs, L Scheller, T Strittmatter, P Saxena, ... Nucleic Acids Research 48 (12), e67-e67, 2020 | 6 | 2020 |
Rational design of small‐molecule responsive protein switches S Shui, S Buckley, L Scheller, BE Correia Protein Science 32 (10), e4774, 2023 | 2 | 2023 |
Synthetic receptors for sensing soluble molecules with mammalian cells L Scheller Mammalian Cell Engineering: Methods and Protocols, 15-33, 2021 | 2 | 2021 |
A bottom-up approach for the de novo design of functional proteins C Yang, F Sesterhenn, J Bonet, E van Aalen, L Scheller, LA Abriata, ... bioRxiv, 2020.03. 11.988071, 2020 | 2 | 2020 |
Dual ON/OFF-switch chimeric antigen receptor controlled by two clinically approved drugs GMP Giordano Attianese, S Shui, E Cribioli, M Triboulet, L Scheller, ... Proceedings of the National Academy of Sciences 121 (44), e2405085121, 2024 | 1 | 2024 |
Targeting protein–ligand neosurfaces with a generalizable deep learning tool A Marchand, S Buckley, A Schneuing, M Pacesa, M Elia, P Gainza, ... Nature, 1-10, 2025 | | 2025 |
Targeting protein-ligand neosurfaces using a generalizable deep learning approach A Marchand, S Buckley, A Schneuing, M Pacesa, P Gainza, E Elizarova, ... bioRxiv, 2024.03. 25.585721, 2024 | | 2024 |