| Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins J Seong, A Tajik, J Sun, JL Guan, MJ Humphries, SE Craig, A Shekaran, ... Proceedings of the National Academy of Sciences 110 (48), 19372-19377, 2013 | 204 | 2013 |
| Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression Y Tan, A Tajik, J Chen, Q Jia, F Chowdhury, L Wang, J Chen, S Zhang, ... Nature communications 5 (1), 4619, 2014 | 201 | 2014 |
| Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells TJ Kim, J Seong, M Ouyang, J Sun, S Lu, JP Hong, N Wang, Y Wang Journal of cellular physiology 218 (2), 285-293, 2009 | 179 | 2009 |
| Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer J Seong, M Ouyang, T Kim, J Sun, PC Wen, S Lu, Y Zhuo, NM Llewellyn, ... Nature communications 2 (1), 406, 2011 | 148 | 2011 |
| Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs TJ Kim, C Joo, J Seong, R Vafabakhsh, EL Botvinick, MW Berns, ... Elife 4, e04876, 2015 | 118 | 2015 |
| Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging M Ouyang, S Lu, XY Li, J Xu, J Seong, BNG Giepmans, JYJ Shyy, ... Journal of Biological Chemistry 283 (25), 17740-17748, 2008 | 99 | 2008 |
| Mechanotransduction at focal adhesions: from physiology to cancer development J Seong, N Wang, Y Wang Journal of cellular and molecular medicine 17 (5), 597-604, 2013 | 96 | 2013 |
| Activation of RIG-I-mediated antiviral signaling triggers autophagy through the MAVS-TRAF6-Beclin-1 signaling axis NR Lee, J Ban, NJ Lee, CM Yi, JY Choi, H Kim, JK Lee, J Seong, NH Cho, ... Frontiers in immunology 9, 2096, 2018 | 86 | 2018 |
| Visualization of Src activity at different compartments of the plasma membrane by FRET imaging J Seong, S Lu, M Ouyang, H Huang, J Zhang, MC Frame, Y Wang Chemistry & biology 16 (1), 48-57, 2009 | 85 | 2009 |
| N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways M Ouyang, S Lu, T Kim, CE Chen, J Seong, DE Leckband, F Wang, ... Nature communications 4 (1), 1589, 2013 | 70 | 2013 |
| The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging S Lu, M Ouyang, J Seong, J Zhang, S Chien, Y Wang PLoS computational biology 4 (7), e1000127, 2008 | 65 | 2008 |
| Genetically encoded biosensors based on fluorescent proteins H Kim, J Ju, HN Lee, H Chun, J Seong Sensors 21 (3), 795, 2021 | 54 | 2021 |
| Single molecular force across single integrins dictates cell spreading F Chowdhury, ITS Li, BJ Leslie, S Doğanay, R Singh, X Wang, J Seong, ... Integrative Biology 7 (10), 1265-1271, 2015 | 52 | 2015 |
| Polyethylenimine‐based antisense oligodeoxynucleotides of IL‐4 suppress the production of IL‐4 in a murine model of airway inflammation JH Seong, KM Lee, ST Kim, SE Jin, CK Kim The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2006 | 45 | 2006 |
| Optobiochemistry: genetically encoded control of protein activity by light J Seong, MZ Lin Annual Review of Biochemistry 90 (1), 475-501, 2021 | 37 | 2021 |
| Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions J Sun, L Lei, CM Tsai, Y Wang, Y Shi, M Ouyang, S Lu, J Seong, TJ Kim, ... Nature communications 8 (1), 477, 2017 | 34 | 2017 |
| RhoA GTPase phosphorylated at tyrosine 42 by src kinase binds to β-catenin and contributes transcriptional regulation of vimentin upon Wnt3A JG Kim, S Mahmud, JK Min, YB Lee, H Kim, DC Kang, HS Park, J Seong, ... Redox Biology 40, 101842, 2021 | 31 | 2021 |
| In-situ coupling between kinase activities and protein dynamics within single focal adhesions Y Wu, K Zhang, J Seong, J Fan, S Chien, Y Wang, S Lu Scientific reports 6 (1), 29377, 2016 | 29 | 2016 |
| Live cell imaging of Src/FAK signaling by FRET J Seong, S Lu, Y Wang Cellular and molecular bioengineering 4, 138-147, 2011 | 27 | 2011 |
| FRET-based visualization of PDGF receptor activation at membrane microdomains J Seong, M Huang, KM Sim, H Kim, Y Wang Scientific Reports 7 (1), 1593, 2017 | 26 | 2017 |
Ning WangProfessorVerified email at northeastern.edu
