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Roosheel Patel
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Mapping systemic inflammation and antibody responses in multisystem inflammatory syndrome in children (MIS-C)
CN Gruber, RS Patel, R Trachtman, L Lepow, F Amanat, F Krammer, ...
Cell 183 (4), 982-995. e14, 2020
5972020
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
L Miorin, T Kehrer, MT Sanchez-Aparicio, K Zhang, P Cohen, RS Patel, ...
Proceedings of the National Academy of Sciences 117 (45), 28344-28354, 2020
5272020
Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
J Taft, M Markson, D Legarda, R Patel, M Chan, L Malle, A Richardson, ...
Cell 184 (17), 4447-4463. e20, 2021
1072021
The NF-κB transcriptional footprint is essential for SARS-CoV-2 replication
BE Nilsson-Payant, S Uhl, A Grimont, AS Doane, P Cohen, RS Patel, ...
Journal of Virology 95 (23), 10.1128/jvi. 01257-21, 2021
892021
An ACE2 Triple Decoy that neutralizes SARS-CoV-2 shows enhanced affinity for virus variants
S Tanaka, G Nelson, CA Olson, O Buzko, W Higashide, A Shin, ...
Scientific Reports 11 (1), 12740, 2021
662021
Use of chimeric type IV secretion systems to define contributions of outer membrane subassemblies for contact‐dependent translocation
JE Gordon, TRD Costa, RS Patel, C Gonzalez‐Rivera, MK Sarkar, ...
Molecular Microbiology 105 (2), 273-293, 2017
552017
Autoimmunity in Down’s syndrome via cytokines, CD4 T cells and CD11c+ B cells
L Malle, RS Patel, M Martin-Fernandez, OJ Stewart, Q Philippot, S Buta, ...
Nature 615 (7951), 305-314, 2023
522023
Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor
O Danziger, RS Patel, EJ DeGrace, MR Rosen, BR Rosenberg
PLoS Pathogens 18 (4), e1010464, 2022
472022
Single-cell resolution landscape of equine peripheral blood mononuclear cells reveals diverse cell types including T-bet+ B cells
RS Patel, JE Tomlinson, TJ Divers, GR Van de Walle, BR Rosenberg
BMC biology 19, 1-18, 2021
392021
Single-cell RNA sequencing of equine mesenchymal stromal cells from primary donor-matched tissue sources reveals functional heterogeneity in immune modulation and cell motility
RM Harman, RS Patel, JC Fan, JE Park, BR Rosenberg, GR Van de Walle
Stem cell research & therapy 11, 1-15, 2020
382020
A next generation bivalent human Ad5 COVID-19 vaccine delivering both spike and nucleocapsid antigens elicits Th1 dominant CD4+, CD8+ T-cell and neutralizing antibody responses
A Rice, M Verma, A Shin, L Zakin, P Sieling, S Tanaka, H Adisetiyo, J Taft, ...
BioRxiv, 2020.07. 29.227595, 2020
372020
Two pKM101‐encoded proteins, the pilus‐tip protein TraC and Pep, assemble on the Escherichia coli cell surface as adhesins required for efficient conjugative …
C González‐Rivera, P Khara, D Awad, R Patel, YG Li, M Bogisch, ...
Molecular microbiology 111 (1), 96-117, 2019
332019
Transcriptional profiling of mESC-derived tendon and fibrocartilage cell fate switch
DA Kaji, AM Montero, R Patel, AH Huang
Nature Communications 12 (1), 4208, 2021
272021
Pathogenesis, MicroRNA‐122 gene‐regulation, and protective immune responses after acute equine hepacivirus infection
JE Tomlinson, R Wolfisberg, U Fahnøe, RS Patel, S Trivedi, A Kumar, ...
Hepatology 74 (3), 1148-1163, 2021
262021
ISG15 deficiency restricts HIV-1 infection
D Jurczyszak, L Manganaro, S Buta, C Gruber, M Martin-Fernandez, J Taft, ...
PLoS Pathogens 18 (3), e1010405, 2022
222022
Prime hAd5 spike+ nucleocapsid vaccination induces ten-fold increases in mean T-cell responses in phase 1 subjects that are sustained against spike variants
P Sieling, T King, R Wong, A Nguyen, K Wnuk, E Gabitzsch, A Rice, ...
medRxiv, 2021.04. 05.21254940, 2021
172021
ISG15 protects human Tregs from interferon alpha‐induced contraction in a cell‐intrinsic fashion
I Pacella, FR Spinelli, M Severa, E Timperi, G Tucci, M Zagaglioni, ...
Clinical & Translational Immunology 9 (12), e1221, 2020
122020
Atypical inflammatory syndrome triggered by SARS-CoV-2 in infants with Down syndrome
L Malle, P Bastard, A Martin-Nalda, T Carpenter, D Bush, R Patel, ...
Journal of clinical immunology 41 (7), 1457-1462, 2021
112021
Individuals with JAK1 variants are affected by syndromic features encompassing autoimmunity, atopy, colitis, and dermatitis
ME Horesh, M Martin-Fernandez, C Gruber, S Buta, T Le Voyer, ...
Journal of Experimental Medicine 221 (6), e20232387, 2024
102024
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation
D Torre, YS Fstkchyan, JSY Ho, Y Cheon, RS Patel, EJ Degrace, ...
Molecular cell 83 (23), 4255-4271. e9, 2023
82023
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