Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9 C Li, X Guan, T Du, W Jin, B Wu, Y Liu, P Wang, B Hu, GE Griffin, ... Journal of General Virology 96 (8), 2381-2393, 2015 | 256 | 2015 |
In vivo HSC prime editing rescues sickle cell disease in a mouse model C Li, A Georgakopoulou, GA Newby, PJ Chen, KA Everette, K Paschoudi, ... Blood, The Journal of the American Society of Hematology 141 (17), 2085-2099, 2023 | 88 | 2023 |
Reactivation of γ-globin in adult β-YAC mice after ex vivo and in vivo hematopoietic stem cell genome editing C Li, N Psatha, P Sova, S Gil, H Wang, J Kim, C Kulkarni, C Valensisi, ... Blood, The Journal of the American Society of Hematology 131 (26), 2915-2928, 2018 | 83 | 2018 |
HDAd5/35++ adenovirus vector expressing anti-CRISPR peptides decreases CRISPR/Cas9 toxicity in human hematopoietic stem cells C Li, N Psatha, S Gil, H Wang, T Papayannopoulou, A Lieber Molecular Therapy-Methods & Clinical Development 9, 390-401, 2018 | 76 | 2018 |
In vivo HSPC gene therapy with base editors allows for efficient reactivation of fetal γ-globin in β-YAC mice C Li, A Georgakopoulou, A Mishra, S Gil, RD Hawkins, E Yannaki, ... Blood advances 5 (4), 1122-1135, 2021 | 69 | 2021 |
In vivo HSC gene therapy using a bi-modular HDAd5/35++ vector cures sickle cell disease in a mouse model C Li, H Wang, A Georgakopoulou, S Gil, E Yannaki, A Lieber Molecular Therapy 29 (2), 822-837, 2021 | 67 | 2021 |
DC-SIGN as an attachment factor mediates Japanese encephalitis virus infection of human dendritic cells via interaction with a single high-mannose residue of viral E glycoprotein P Wang, K Hu, S Luo, M Zhang, X Deng, C Li, W Jin, B Hu, S He, M Li, ... Virology 488, 108-119, 2016 | 65 | 2016 |
Herpes simplex virus type 2 infection of human epithelial cells induces CXCL9 expression and CD4+ T cell migration via activation of p38-CCAAT/enhancer-binding protein-β pathway W Huang, K Hu, S Luo, M Zhang, C Li, W Jin, Y Liu, GE Griffin, ... The Journal of Immunology 188 (12), 6247-6257, 2012 | 59 | 2012 |
In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia H Wang, A Georgakopoulou, N Psatha, C Li, C Capsali, HB Samal, ... The Journal of clinical investigation 129 (2), 598-615, 2019 | 57 | 2019 |
Adenovirus vectors in hematopoietic stem cell genome editing C Li, A Lieber FEBS letters 593 (24), 3623-3648, 2019 | 53 | 2019 |
HSV-2 immediate-early protein US1 inhibits IFN-β production by suppressing association of IRF-3 with IFN-β promoter M Zhang, Y Liu, P Wang, X Guan, S He, S Luo, C Li, K Hu, W Jin, T Du, ... The Journal of Immunology 194 (7), 3102-3115, 2015 | 46 | 2015 |
A combined in vivo HSC transduction/selection approach results in efficient and stable gene expression in peripheral blood cells in mice H Wang, M Richter, N Psatha, C Li, J Kim, J Liu, A Ehrhardt, SK Nilsson, ... Molecular Therapy-Methods & Clinical Development 8, 52-64, 2018 | 43 | 2018 |
Desmoglein-2 as a prognostic and biomarker in ovarian cancer J Kim, P Beidler, H Wang, C Li, A Quassab, C Coles, C Drescher, D Carter, ... Cancer Biology & Therapy 21 (12), 1154-1162, 2020 | 35 | 2020 |
Targeted integration and high-level transgene expression in AAVS1 transgenic mice after in vivo HSC transduction with HDAd5/35++ vectors C Li, AS Mishra, S Gil, M Wang, A Georgakopoulou, T Papayannopoulou, ... Molecular Therapy 27 (12), 2195-2212, 2019 | 35 | 2019 |
Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins Y Liu, S Luo, S He, M Zhang, P Wang, C Li, W Huang, B Hu, GE Griffin, ... Virology 475, 96-109, 2015 | 35 | 2015 |
Integrating HDAd5/35++ vectors as a new platform for HSC gene therapy of hemoglobinopathies C Li, N Psatha, H Wang, M Singh, HB Samal, W Zhang, A Ehrhardt, ... Molecular Therapy Methods & Clinical Development 9, 142-152, 2018 | 33 | 2018 |
Intravascular clearance of disseminating Cryptococcus neoformans in the brain can be improved by enhancing neutrophil recruitment in mice D Sun, M Zhang, G Liu, H Wu, C Li, H Zhou, X Zhang, M Shi European journal of immunology 46 (7), 1704-1714, 2016 | 33 | 2016 |
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors C Li, H Wang, S Gil, A Germond, C Fountain, A Baldessari, J Kim, Z Liu, ... Molecular Therapy-Methods & Clinical Development 24, 127-141, 2022 | 32 | 2022 |
Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo N Psatha, A Georgakopoulou, C Li, V Nandakumar, G Georgolopoulos, ... Blood, The Journal of the American Society of Hematology 138 (17), 1540-1553, 2021 | 30 | 2021 |
DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer W Jin, C Li, T Du, K Hu, X Huang, Q Hu Virology 458, 83-92, 2014 | 29 | 2014 |