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Chang Li
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Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9
C Li, X Guan, T Du, W Jin, B Wu, Y Liu, P Wang, B Hu, GE Griffin, ...
Journal of General Virology 96 (8), 2381-2393, 2015
2562015
In vivo HSC prime editing rescues sickle cell disease in a mouse model
C Li, A Georgakopoulou, GA Newby, PJ Chen, KA Everette, K Paschoudi, ...
Blood, The Journal of the American Society of Hematology 141 (17), 2085-2099, 2023
882023
Reactivation of γ-globin in adult β-YAC mice after ex vivo and in vivo hematopoietic stem cell genome editing
C Li, N Psatha, P Sova, S Gil, H Wang, J Kim, C Kulkarni, C Valensisi, ...
Blood, The Journal of the American Society of Hematology 131 (26), 2915-2928, 2018
832018
HDAd5/35++ adenovirus vector expressing anti-CRISPR peptides decreases CRISPR/Cas9 toxicity in human hematopoietic stem cells
C Li, N Psatha, S Gil, H Wang, T Papayannopoulou, A Lieber
Molecular Therapy-Methods & Clinical Development 9, 390-401, 2018
762018
In vivo HSPC gene therapy with base editors allows for efficient reactivation of fetal γ-globin in β-YAC mice
C Li, A Georgakopoulou, A Mishra, S Gil, RD Hawkins, E Yannaki, ...
Blood advances 5 (4), 1122-1135, 2021
692021
In vivo HSC gene therapy using a bi-modular HDAd5/35++ vector cures sickle cell disease in a mouse model
C Li, H Wang, A Georgakopoulou, S Gil, E Yannaki, A Lieber
Molecular Therapy 29 (2), 822-837, 2021
672021
DC-SIGN as an attachment factor mediates Japanese encephalitis virus infection of human dendritic cells via interaction with a single high-mannose residue of viral E glycoprotein
P Wang, K Hu, S Luo, M Zhang, X Deng, C Li, W Jin, B Hu, S He, M Li, ...
Virology 488, 108-119, 2016
652016
Herpes simplex virus type 2 infection of human epithelial cells induces CXCL9 expression and CD4+ T cell migration via activation of p38-CCAAT/enhancer-binding protein-β pathway
W Huang, K Hu, S Luo, M Zhang, C Li, W Jin, Y Liu, GE Griffin, ...
The Journal of Immunology 188 (12), 6247-6257, 2012
592012
In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia
H Wang, A Georgakopoulou, N Psatha, C Li, C Capsali, HB Samal, ...
The Journal of clinical investigation 129 (2), 598-615, 2019
572019
Adenovirus vectors in hematopoietic stem cell genome editing
C Li, A Lieber
FEBS letters 593 (24), 3623-3648, 2019
532019
HSV-2 immediate-early protein US1 inhibits IFN-β production by suppressing association of IRF-3 with IFN-β promoter
M Zhang, Y Liu, P Wang, X Guan, S He, S Luo, C Li, K Hu, W Jin, T Du, ...
The Journal of Immunology 194 (7), 3102-3115, 2015
462015
A combined in vivo HSC transduction/selection approach results in efficient and stable gene expression in peripheral blood cells in mice
H Wang, M Richter, N Psatha, C Li, J Kim, J Liu, A Ehrhardt, SK Nilsson, ...
Molecular Therapy-Methods & Clinical Development 8, 52-64, 2018
432018
Desmoglein-2 as a prognostic and biomarker in ovarian cancer
J Kim, P Beidler, H Wang, C Li, A Quassab, C Coles, C Drescher, D Carter, ...
Cancer Biology & Therapy 21 (12), 1154-1162, 2020
352020
Targeted integration and high-level transgene expression in AAVS1 transgenic mice after in vivo HSC transduction with HDAd5/35++ vectors
C Li, AS Mishra, S Gil, M Wang, A Georgakopoulou, T Papayannopoulou, ...
Molecular Therapy 27 (12), 2195-2212, 2019
352019
Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins
Y Liu, S Luo, S He, M Zhang, P Wang, C Li, W Huang, B Hu, GE Griffin, ...
Virology 475, 96-109, 2015
352015
Integrating HDAd5/35++ vectors as a new platform for HSC gene therapy of hemoglobinopathies
C Li, N Psatha, H Wang, M Singh, HB Samal, W Zhang, A Ehrhardt, ...
Molecular Therapy Methods & Clinical Development 9, 142-152, 2018
332018
Intravascular clearance of disseminating Cryptococcus neoformans in the brain can be improved by enhancing neutrophil recruitment in mice
D Sun, M Zhang, G Liu, H Wu, C Li, H Zhou, X Zhang, M Shi
European journal of immunology 46 (7), 1704-1714, 2016
332016
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors
C Li, H Wang, S Gil, A Germond, C Fountain, A Baldessari, J Kim, Z Liu, ...
Molecular Therapy-Methods & Clinical Development 24, 127-141, 2022
322022
Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo
N Psatha, A Georgakopoulou, C Li, V Nandakumar, G Georgolopoulos, ...
Blood, The Journal of the American Society of Hematology 138 (17), 1540-1553, 2021
302021
DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer
W Jin, C Li, T Du, K Hu, X Huang, Q Hu
Virology 458, 83-92, 2014
292014
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