A next generation connectivity map: L1000 platform and the first 1,000,000 profiles A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ... Cell 171 (6), 1437-1452. e17, 2017 | 2953 | 2017 |
High-throughput phenotyping of lung cancer somatic mutations AH Berger, AN Brooks, X Wu, Y Shrestha, C Chouinard, F Piccioni, ... Cancer cell 30 (2), 214-228, 2016 | 233 | 2016 |
Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map I Smith, PG Greenside, T Natoli, DL Lahr, D Wadden, I Tirosh, R Narayan, ... PLoS biology 15 (11), e2003213, 2017 | 225 | 2017 |
Fabrication and gas sensing performance of parallel assemblies of metal oxide nanotubes supported by porous aluminum oxide membranes R Artzi-Gerlitz, KD Benkstein, DL Lahr, JL Hertz, CB Montgomery, ... Sensors and Actuators B: Chemical 136 (1), 257-264, 2009 | 90 | 2009 |
A library of phosphoproteomic and chromatin signatures for characterizing cellular responses to drug perturbations L Litichevskiy, R Peckner, JG Abelin, JK Asiedu, AL Creech, JF Davis, ... Cell systems 6 (4), 424-443. e7, 2018 | 86 | 2018 |
Catalyzed CO oxidation at 70 K on an extended Au/Ni surface alloy DL Lahr, ST Ceyer Journal of the American Chemical Society 128 (6), 1800-1801, 2006 | 75 | 2006 |
The GCTx format and cmap {Py, R, M, J} packages: resources for optimized storage and integrated traversal of annotated dense matrices OM Enache, DL Lahr, TE Natoli, L Litichevskiy, D Wadden, C Flynn, ... Bioinformatics 35 (8), 1427-1429, 2019 | 67 | 2019 |
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types EA Howe, A de Souza, DL Lahr, S Chatwin, P Montgomery, BR Alexander, ... Nucleic acids research 43 (D1), D1163-D1170, 2015 | 29 | 2015 |
An overview of the challenges in designing, integrating, and delivering BARD: a public chemical-biology resource and query portal for multiple organizations, locations, and … A de Souza, JA Bittker, DL Lahr, S Brudz, S Chatwin, TI Oprea, A Waller, ... Journal of biomolecular screening 19 (5), 614-627, 2014 | 29 | 2014 |
Inducing analytical orthogonality in tungsten oxide-based microsensors using materials structure and dynamic temperature control KD Benkstein, B Raman, DL Lahr, JE Bonevich, S Semancik Sensors and Actuators B: Chemical 137 (1), 48-55, 2009 | 17 | 2009 |
Reactions of gas phase H atoms with ethylene, acetylene and ethane adsorbed on Ni (111) T Bürgi, TR Trautman, M Gostein, DL Lahr, KL Haug, ST Ceyer Surface science 501 (1-2), 49-73, 2002 | 17 | 2002 |
Origin of electrical signals for plasma etching end point detection: Comparison of end point signals and electron density MA Sobolewski, DL Lahr Journal of Vacuum Science & Technology A 30 (5), 2012 | 14 | 2012 |
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries CA Mulrooney, DL Lahr, MJ Quintin, W Youngsaye, D Moccia, JK Asiedu, ... Journal of computer-aided molecular design 27, 455-468, 2013 | 11 | 2013 |
A combinatorial study of thin-film process variables using microhotplates DL Lahr, JL Hertz, S Semancik Journal of Microelectromechanical Systems 19 (2), 239-245, 2010 | 8 | 2010 |
Preclinical validation of target engagement assays and investigation of mechanistic impacts of FHD-609, a clinical-stage BRD9 degrader being developed for the treatment of … M Collins, J Wan, V Garbitt-Amaral, B Antonakos, HJ Wu, C Xu, DL Lahr, ... strategies 36, 936-950, 2022 | 7 | 2022 |
Combinatorial Characterization of Chemiresistive Films Using Microhotplates JL Hertz, DL Lahr, S Semancik IEEE Sensors Journal 12 (5), 1459-1460, 2011 | 4 | 2011 |
Abstract A049: Investigation of FHD-609, a potent degrader of BRD9, in preclinical models of acute myeloid leukemia (AML) C Dominici, D Mayhew, A Adam, F Uzan, V Garbitt-Amaral, O Mikse, ... Molecular Cancer Therapeutics 22 (12_Supplement), A049-A049, 2023 | 3 | 2023 |
Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers RC Centore, LMM Soares, S Topal, RG Vaswani, K Ichikawa, Z Li, H Fan, ... bioRxiv, 2023.09. 11.557162, 2023 | 3 | 2023 |
Discovery of novel BAF inhibitors for the treatment of transcription factor-driven cancers RC Centore, LM Soares, RG Vaswani, K Ichikawa, Z Li, H Fan, J Setser, ... Cancer Research 81 (13_Supplement), 1224-1224, 2021 | 3 | 2021 |
Molecular oxygen adsorbates at a Au/Ni (111) surface alloy and their role in catalytic CO oxidation at 70-250 K DL Lahr Massachusetts Institute of Technology, 2006 | 3 | 2006 |