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Simone Brixius-Anderko
Simone Brixius-Anderko
Assistant Professor University of Pittsburgh School of Pharmacy
Verified email at pitt.edu - Homepage
Title
Cited by
Cited by
Year
The CYP11B subfamily
L Schiffer, S Anderko, F Hannemann, A Eiden-Plach, R Bernhardt
The Journal of steroid biochemistry and molecular biology 151, 38-51, 2015
762015
CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2
J Malikova, S Brixius-Anderko, SS Udhane, S Parween, B Dick, ...
The Journal of steroid biochemistry and molecular biology 174, 192-200, 2017
592017
A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale
L Schiffer, S Anderko, A Hobler, F Hannemann, N Kagawa, R Bernhardt
Microbial Cell Factories 14, 1-12, 2015
462015
Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design
S Brixius-Anderko, EE Scott
Journal of Biological Chemistry 294 (2), 453-460, 2019
392019
A CYP21A2 based whole-cell system in Escherichia coli for the biotechnological production of premedrol
S Brixius-Anderko, L Schiffer, F Hannemann, B Janocha, R Bernhardt
Microbial Cell Factories 14, 1-14, 2015
352015
Metabolism of oral turinabol by human steroid hormone–synthesizing cytochrome P450 enzymes
L Schiffer, S Brixius-Anderko, F Hannemann, J Zapp, J Neunzig, M Thevis, ...
Drug Metabolism and Disposition 44 (2), 227-237, 2016
332016
Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin
S Brixius-Anderko, EE Scott
Journal of Biological Chemistry 296, 2021
312021
Aldosterone synthase structure with Cushing disease drug LCI699 highlights avenues for selective CYP11B drug design
S Brixius-Anderko, EE Scott
Hypertension 78 (3), 751-759, 2021
142021
An indole‐deficient Escherichia coli strain improves screening of cytochromes P450 for biotechnological applications
S Brixius‐Anderko, F Hannemann, M Ringle, Y Khatri, R Bernhardt
Biotechnology and Applied Biochemistry 64 (3), 315-326, 2017
142017
Biotransformation of the mineralocorticoid receptor antagonists spironolactone and canrenone by human CYP11B1 and CYP11B2: characterization of the products and their influence …
L Schiffer, AR Müller, A Hobler, S Brixius-Anderko, J Zapp, F Hannemann, ...
The Journal of Steroid Biochemistry and Molecular Biology 163, 68-76, 2016
132016
Discovery of novel non-steroidal cytochrome P450 17A1 inhibitors as potential prostate cancer agents
TM Wróbel, O Rogova, KL Andersen, R Yadav, S Brixius-Anderko, ...
International Journal of Molecular Sciences 21 (14), 4868, 2020
102020
Redox partner adrenodoxin alters cytochrome P450 11B1 ligand binding and inhibition
CL Loomis, S Brixius-Anderko, EE Scott
Journal of inorganic biochemistry 235, 111934, 2022
92022
HIV drug efavirenz inhibits CYP21A2 activity with possible clinical implications
J Malikova, T Zingg, R Fingerhut, S Sluka, M Grössl, S Brixius-Anderko, ...
Hormone research in paediatrics 91 (4), 262-270, 2019
62019
Identification and circumvention of bottlenecks in CYP21A2‐mediated premedrol production using recombinant Escherichia coli
L König, S Brixius‐Anderko, M Milhim, D Tavouli‐Abbas, MC Hutter, ...
Biotechnology and Bioengineering 117 (4), 901-911, 2020
52020
Deciphering the Role of Fatty Acid–Metabolizing CYP4F11 in Lung Cancer and Its Potential As a Drug Target
H Jia, B Brixius, C Bocianoski, S Ray, DR Koes, S Brixius-Anderko
Drug Metabolism and Disposition 52 (2), 69-79, 2024
42024
Supporting nonlinear careers to diversify science
AL Vlasits, ML Smith, M Maldonado, S Brixius-Anderko
PLoS Biology 21 (9), e3002291, 2023
22023
Mixed-culture fermentation for enhanced C21-hydroxylation of glucocorticoids
L König, S Szczesny, S Brixius-Anderko, R Bernhardt, F Hannemann
Journal of biotechnology 314, 14-24, 2020
22020
Biotechnological application of steroidogenic cytochromes P450
S Brixius-Anderko
22016
Recruiting women faculty through inclusive, family-friendly practices
R San Martin, A Moffitt, T Loveless, S Brixius-Anderko
Trends in Biochemical Sciences 48 (4), 311-314, 2023
12023
21-hydroxylation of steroids
C Lattemann, T Stillger, B Janocha, HF Rasser, S Rissom, S Anderko, ...
US Patent 10,385,376, 2019
12019
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