The CYP11B subfamily L Schiffer, S Anderko, F Hannemann, A Eiden-Plach, R Bernhardt The Journal of steroid biochemistry and molecular biology 151, 38-51, 2015 | 76 | 2015 |
CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2 J Malikova, S Brixius-Anderko, SS Udhane, S Parween, B Dick, ... The Journal of steroid biochemistry and molecular biology 174, 192-200, 2017 | 59 | 2017 |
A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale L Schiffer, S Anderko, A Hobler, F Hannemann, N Kagawa, R Bernhardt Microbial Cell Factories 14, 1-12, 2015 | 46 | 2015 |
Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design S Brixius-Anderko, EE Scott Journal of Biological Chemistry 294 (2), 453-460, 2019 | 39 | 2019 |
A CYP21A2 based whole-cell system in Escherichia coli for the biotechnological production of premedrol S Brixius-Anderko, L Schiffer, F Hannemann, B Janocha, R Bernhardt Microbial Cell Factories 14, 1-14, 2015 | 35 | 2015 |
Metabolism of oral turinabol by human steroid hormone–synthesizing cytochrome P450 enzymes L Schiffer, S Brixius-Anderko, F Hannemann, J Zapp, J Neunzig, M Thevis, ... Drug Metabolism and Disposition 44 (2), 227-237, 2016 | 33 | 2016 |
Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin S Brixius-Anderko, EE Scott Journal of Biological Chemistry 296, 2021 | 31 | 2021 |
Aldosterone synthase structure with Cushing disease drug LCI699 highlights avenues for selective CYP11B drug design S Brixius-Anderko, EE Scott Hypertension 78 (3), 751-759, 2021 | 14 | 2021 |
An indole‐deficient Escherichia coli strain improves screening of cytochromes P450 for biotechnological applications S Brixius‐Anderko, F Hannemann, M Ringle, Y Khatri, R Bernhardt Biotechnology and Applied Biochemistry 64 (3), 315-326, 2017 | 14 | 2017 |
Biotransformation of the mineralocorticoid receptor antagonists spironolactone and canrenone by human CYP11B1 and CYP11B2: characterization of the products and their influence … L Schiffer, AR Müller, A Hobler, S Brixius-Anderko, J Zapp, F Hannemann, ... The Journal of Steroid Biochemistry and Molecular Biology 163, 68-76, 2016 | 13 | 2016 |
Discovery of novel non-steroidal cytochrome P450 17A1 inhibitors as potential prostate cancer agents TM Wróbel, O Rogova, KL Andersen, R Yadav, S Brixius-Anderko, ... International Journal of Molecular Sciences 21 (14), 4868, 2020 | 10 | 2020 |
Redox partner adrenodoxin alters cytochrome P450 11B1 ligand binding and inhibition CL Loomis, S Brixius-Anderko, EE Scott Journal of inorganic biochemistry 235, 111934, 2022 | 9 | 2022 |
HIV drug efavirenz inhibits CYP21A2 activity with possible clinical implications J Malikova, T Zingg, R Fingerhut, S Sluka, M Grössl, S Brixius-Anderko, ... Hormone research in paediatrics 91 (4), 262-270, 2019 | 6 | 2019 |
Identification and circumvention of bottlenecks in CYP21A2‐mediated premedrol production using recombinant Escherichia coli L König, S Brixius‐Anderko, M Milhim, D Tavouli‐Abbas, MC Hutter, ... Biotechnology and Bioengineering 117 (4), 901-911, 2020 | 5 | 2020 |
Deciphering the Role of Fatty Acid–Metabolizing CYP4F11 in Lung Cancer and Its Potential As a Drug Target H Jia, B Brixius, C Bocianoski, S Ray, DR Koes, S Brixius-Anderko Drug Metabolism and Disposition 52 (2), 69-79, 2024 | 4 | 2024 |
Supporting nonlinear careers to diversify science AL Vlasits, ML Smith, M Maldonado, S Brixius-Anderko PLoS Biology 21 (9), e3002291, 2023 | 2 | 2023 |
Mixed-culture fermentation for enhanced C21-hydroxylation of glucocorticoids L König, S Szczesny, S Brixius-Anderko, R Bernhardt, F Hannemann Journal of biotechnology 314, 14-24, 2020 | 2 | 2020 |
Biotechnological application of steroidogenic cytochromes P450 S Brixius-Anderko | 2 | 2016 |
Recruiting women faculty through inclusive, family-friendly practices R San Martin, A Moffitt, T Loveless, S Brixius-Anderko Trends in Biochemical Sciences 48 (4), 311-314, 2023 | 1 | 2023 |
21-hydroxylation of steroids C Lattemann, T Stillger, B Janocha, HF Rasser, S Rissom, S Anderko, ... US Patent 10,385,376, 2019 | 1 | 2019 |