| Toward in silico structure-based ADMET prediction in drug discovery G Moroy, VY Martiny, P Vayer, BO Villoutreix, MA Miteva Drug discovery today 17 (1-2), 44-55, 2012 | 329 | 2012 |
| Neutrophil elastase as a target in lung cancer G Moroy, A JP Alix, J Sapi, W Hornebeck, E Bourguet Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2012 | 91 | 2012 |
| PEP-SiteFinder: a tool for the blind identification of peptide binding sites on protein surfaces A Saladin, J Rey, P Thévenet, M Zacharias, G Moroy, P Tufféry Nucleic acids research 42 (W1), W221-W226, 2014 | 89 | 2014 |
| A fibrillin-1-fragment containing the elastin-binding-protein GxxPG consensus sequence upregulates matrix metalloproteinase-1: biochemical and computational analysis P Booms, A Ney, F Barthel, G Moroy, D Counsell, C Gille, G Guo, R Pregla, ... Journal of molecular and cellular cardiology 40 (2), 234-246, 2006 | 79 | 2006 |
| SeamDock: an interactive and collaborative online docking resource to assist small compound molecular docking S Murail, SJ De Vries, J Rey, G Moroy, P Tufféry Frontiers in Molecular Biosciences 8, 716466, 2021 | 59 | 2021 |
| Molecular basis for Bcl-2 homology 3 domain recognition in the Bcl-2 protein family: identification of conserved hot spot interactions G Moroy, E Martin, A Dejaegere, RH Stote Journal of Biological Chemistry 284 (26), 17499-17511, 2009 | 51 | 2009 |
| Introduction of the 4-(4-bromophenyl) benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity G LeDour, G Moroy, M Rouffet, E Bourguet, D Guillaume, M Decarme, ... Bioorganic & medicinal chemistry 16 (18), 8745-8759, 2008 | 51 | 2008 |
| Structural characterization of human elastin derived peptides containing the GXXP sequence G Moroy, AJP Alix, S Héry‐Huynh Biopolymers: Original Research on Biomolecules 78 (4), 206-220, 2005 | 44 | 2005 |
| Integrated structure- and ligand-based in silico approach to predict inhibition of cytochrome P450 2D6 VY Martiny, P Carbonell, F Chevillard, G Moroy, AB Nicot, P Vayer, ... Bioinformatics 31 (24), 3930-3937, 2015 | 36 | 2015 |
| Simultaneous presence of unsaturation and long alkyl chain at P1′ of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by … G Moroy, C Denhez, H El Mourabit, A Toribio, A Dassonville, M Decarme, ... Bioorganic & medicinal chemistry 15 (14), 4753-4766, 2007 | 34 | 2007 |
| Class I HDAC inhibitors: potential new epigenetic therapeutics for alcohol use disorder (AUD) E Bourguet, K Ozdarska, G Moroy, J Jeanblanc, M Naassila Journal of Medicinal Chemistry 61 (5), 1745-1766, 2017 | 31 | 2017 |
| In silico mechanistic profiling to probe small molecule binding to sulfotransferases VY Martiny, P Carbonell, D Lagorce, BO Villoutreix, G Moroy, MA Miteva PLoS One 8 (9), e73587, 2013 | 31 | 2013 |
| A rational free energy-based approach to understanding and targeting disease-causing missense mutations Z Zhang, S Witham, M Petukh, G Moroy, M Miteva, Y Ikeguchi, E Alexov Journal of the American Medical Informatics Association 20 (4), 643-651, 2013 | 28 | 2013 |
| Sampling of conformational ensemble for virtual screening using molecular dynamics simulations and normal mode analysis G Moroy, O Sperandio, S Rielland, S Khemka, K Druart, D Goyal, ... Future medicinal chemistry 7 (17), 2317-2331, 2015 | 27 | 2015 |
| JNK contributes to Hif-1α regulation in hypoxic neurons X Antoniou, A Sclip, C Ploia, A Colombo, G Moroy, T Borsello Molecules 15 (1), 114-127, 2009 | 23 | 2009 |
| A proposed interaction mechanism between elastin‐derived peptides and the elastin/laminin receptor‐binding domain G Moroy, A Ostuni, A Pepe, AM Tamburro, AJP Alix, S Héry‐Huynh Proteins: Structure, Function, and Bioinformatics 76 (2), 461-476, 2009 | 23 | 2009 |
| Four major channels detected in the cytochrome P450 3A4: a step toward understanding its multispecificity L Benkaidali, F André, G Moroy, B Tangour, F Maurel, M Petitjean International Journal of Molecular Sciences 20 (4), 987, 2019 | 21 | 2019 |
| Dihydroisocoumarin glucosides from stem bark of Caryocar glabrum AA Magid, L Voutquenne-Nazabadioko, G Moroy, C Moretti, C Lavaud Phytochemistry 68 (19), 2439-2443, 2007 | 21 | 2007 |
| Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup® Dietary Supplement: Role of Green Tea Catechins Y Gu, G Moroy, JL Paul, AS Rebillat, M Dierssen, R de La Torre, ... International Journal of Molecular Sciences 21 (4), 1404, 2020 | 20 | 2020 |
| PatchSearch: a web server for off-target protein identification J Rey, I Rasolohery, P Tufféry, F Guyon, G Moroy Nucleic Acids Research 47 (W1), W365-W372, 2019 | 18 | 2019 |
Bruno VilloutreixInsermVerified email at inserm.fr
