Animal models for bone tissue engineering and modelling disease JA McGovern, M Griffin, DW Hutmacher Disease models & mechanisms 11 (4), dmm033084, 2018 | 291 | 2018 |
A preclinical large-animal model for the assessment of critical-size load-bearing bone defect reconstruction DS Sparks, S Saifzadeh, FM Savi, CE Dlaska, A Berner, J Henkel, ... Nature Protocols 15 (3), 877-924, 2020 | 121 | 2020 |
Engineering a humanized bone organ model in mice to study bone metastases LC Martine, BM Holzapfel, JA McGovern, F Wagner, VM Quent, P Hesami, ... Nature protocols 12 (4), 639-663, 2017 | 119 | 2017 |
Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis M Landgraf, CA Lahr, I Kaur, A Shafiee, A Sanchez-Herrero, PW Janowicz, ... Biomaterials 240, 119791, 2020 | 109 | 2020 |
Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality BWC Tse, M Volpert, E Ratther, N Stylianou, M Nouri, K McGowan, ... Oncogene 36 (24), 3417-3427, 2017 | 86 | 2017 |
Rational design of mouse models for cancer research M Landgraf, JA McGovern, P Friedl, DW Hutmacher Trends in biotechnology 36 (3), 242-251, 2018 | 82 | 2018 |
Quantitative comparison of the spreading and invasion of radial growth phase and metastatic melanoma cells in a three-dimensional human skin equivalent model P Haridas, JA McGovern, SDL McElwain, MJ Simpson PeerJ 5, e3754, 2017 | 62 | 2017 |
Quantifying rates of cell migration and cell proliferation in co-culture barrier assays reveals how skin and melanoma cells interact during melanoma spreading and invasion P Haridas, CJ Penington, JA McGovern, DLS McElwain, MJ Simpson Journal of Theoretical Biology 423, 13-25, 2017 | 49 | 2017 |
Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma F Wagner, BM Holzapfel, JA McGovern, A Shafiee, JG Baldwin, ... Biomaterials 171, 230-246, 2018 | 44 | 2018 |
Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair J Evans, G Infusini, J McGovern, L Cuttle, A Webb, T Nebl, L Milla, ... The FASEB Journal 33 (1), 584-605, 2019 | 37 | 2019 |
Mobilizing serum factors and immune cells through exercise to counteract age-related changes in cancer risk JH Hwang, J McGovern, G Minett, P Della Gatta, LA Roberts, J Harris, ... Exercise immunology review 26, 80-99, 2020 | 35 | 2020 |
Attenuated kallikrein‐related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models JA McGovern, C Meinert, SJ De Veer, BG Hollier, TJ Parker, Z Upton British Journal of Dermatology 176 (1), 145-158, 2017 | 34 | 2017 |
Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study A Shafiee, JA McGovern, CA Lahr, C Meinert, D Moi, F Wagner, ... International journal of cancer 143 (6), 1470-1482, 2018 | 31 | 2018 |
Targeting insulin-like growth factor-I and extracellular matrix interactions in melanoma progression B Murekatete, A Shokoohmand, J McGovern, L Mohanty, C Meinert, ... Scientific reports 8 (1), 583, 2018 | 29 | 2018 |
Severe hypoxia and malnutrition collectively contribute to scar fibroblast inhibition and cell apoptosis EC Lynam, Y Xie, R Dawson, J Mcgovern, Z Upton, XQ Wang Wound Repair and Regeneration 23 (5), 664-671, 2015 | 29 | 2015 |
Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo M Landgraf, CA Lahr, A Sanchez-Herrero, C Meinert, A Shokoohmand, ... Bone research 7 (1), 31, 2019 | 27* | 2019 |
Stratum basale keratinocyte expression of the cell‐surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration JA McGovern, JR Heinemann, LJ Burke, R Dawson, TJ Parker, Z Upton, ... British Journal of Dermatology 168 (3), 496-503, 2013 | 27 | 2013 |
Humanization of the prostate microenvironment reduces homing of PC3 prostate cancer cells to human tissue-engineered bone JA McGovern, A Shafiee, F Wagner, CA Lahr, M Landgraf, C Meinert, ... Cancers 10 (11), 438, 2018 | 25 | 2018 |
Human and mouse bones physiologically integrate in a humanized mouse model while maintaining species-specific ultrastructure I Moreno-Jiménez, A Cipitria, A Sánchez-Herrero, AF Van Tol, ... Science Advances 6 (44), eabb9265, 2020 | 23 | 2020 |
GelMA and biomimetic culture allow the engineering of mineralized, adipose, and tumor tissue human microenvironments for the study of advanced prostate cancer in vitro and in vivo A Bessot, J Gunter, D Waugh, JA Clements, DW Hutmacher, J McGovern, ... Advanced Healthcare Materials 12 (14), 2201701, 2023 | 19 | 2023 |