RIT1 oncoproteins escape LZTR1-mediated proteolysis P Castel, A Cheng, A Cuevas-Navarro, DB Everman, AG Papageorge, ... Science 363 (6432), 1226-1230, 2019 | 100 | 2019 |
Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis SR Gundala, C Yang, R Mukkavilli, R Paranjpe, M Brahmbhatt, V Pannu, ... Toxicology and applied pharmacology 280 (1), 86-96, 2014 | 99 | 2014 |
Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach V Pannu, PCG Rida, A Ogden, R Clewley, A Cheng, P Karna, M Lopus, ... Cell death & disease 3 (7), e346-e346, 2012 | 41 | 2012 |
RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity P Castel, S Dharmaiah, MJ Sale, S Messing, G Rizzuto, ... Proceedings of the National Academy of Sciences 118 (33), e2103261118, 2021 | 37 | 2021 |
Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and death A Ogden, A Cheng, PCG Rida, V Pannu, R Osan, R Clewley, R Aneja Cell Death & Disease 5 (5), e1204-e1204, 2014 | 34 | 2014 |
Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis S Donthamsetty, M Brahmbhatt, V Pannu, P Rida, S Ramarathinam, ... Cell Cycle 13 (13), 2056-2255, 2014 | 26 | 2014 |
The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression A Cuevas-Navarro, R Van, A Cheng, A Urisman, P Castel, F McCormick Current Biology 31 (17), 3915-3924. e9, 2021 | 24 | 2021 |
Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs A Cuevas-Navarro, L Rodriguez-Muñoz, J Grego-Bessa, A Cheng, ... Elife 11, e76495, 2022 | 19 | 2022 |
Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization LC Young, R Goldstein de Salazar, SW Han, ZYS Huang, A Merk, M Drew, ... Proceedings of the National Academy of Sciences 120 (5), e2208960120, 2023 | 17 | 2023 |
RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome–associated cardiac hypertrophy A Cuevas-Navarro, M Wagner, R Van, M Swain, S Mo, J Columbus, ... Science Advances 9 (28), eadf4766, 2023 | 16 | 2023 |