| Functional amyloid–from bacteria to humans DM Fowler, AV Koulov, WE Balch, JW Kelly Trends in biochemical sciences 32 (5), 217-224, 2007 | 1212 | 2007 |
| Functional amyloid formation within mammalian tissue DM Fowler, AV Koulov, C Alory-Jost, MS Marks, WE Balch, JW Kelly PLoS biology 4 (1), e6, 2006 | 1036 | 2006 |
| Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis X Wang, J Venable, P LaPointe, DM Hutt, AV Koulov, J Coppinger, ... Cell 127 (4), 803-815, 2006 | 715 | 2006 |
| Semen-derived amyloid fibrils drastically enhance HIV infection J Münch, E Rücker, L Ständker, K Adermann, C Goffinet, M Schindler, ... Cell 131 (6), 1059-1071, 2007 | 657 | 2007 |
| Chloride transport across vesicle and cell membranes by steroid-based receptors AV Koulov, TN Lambert, R Shukla, M Jain, JM Boon, BD Smith, H Li, ... Angewandte Chemie International Edition 42 (40), 4931-4933, 2003 | 214 | 2003 |
| Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis AV Koulov, P LaPointe, B Lu, A Razvi, J Coppinger, MQ Dong, J Matteson, ... Molecular biology of the cell 21 (6), 871-884, 2010 | 199 | 2010 |
| Subcutaneous injection volume of biopharmaceuticals—pushing the boundaries R Mathaes, A Koulov, S Joerg, HC Mahler Journal of pharmaceutical sciences 105 (8), 2255-2259, 2016 | 155 | 2016 |
| Aggregation of Human Recombinant Monoclonal Antibodies Influences the Capacity of Dendritic Cells to Stimulate Adaptive T-Cell Responses In Vitro V Rombach-Riegraf, AC Karle, B Wolf, L Sordé, S Koepke, S Gottlieb, ... PLoS One 9 (1), e86322, 2014 | 152 | 2014 |
| Structure–activity relationships in cholapod anion carriers: enhanced transmembrane chloride transport through substituent tuning BA McNally, AV Koulov, TN Lambert, BD Smith, JB Joos, AL Sisson, ... Chemistry–A European Journal 14 (31), 9599-9606, 2008 | 133 | 2008 |
| The immunogenicity of antibody aggregates in a novel transgenic mouse model J Bessa, S Boeckle, H Beck, T Buckel, S Schlicht, M Ebeling, A Kiialainen, ... Pharmaceutical Research 32, 2344-2359, 2015 | 130 | 2015 |
| Discrimination between silicone oil droplets and protein aggregates in biopharmaceuticals: a novel multiparametric image filter for sub-visible particles in microflow imaging … R Strehl, V Rombach-Riegraf, M Diez, K Egodage, M Bluemel, M Jeschke, ... Pharmaceutical research 29, 594-602, 2012 | 129 | 2012 |
| Detection of apoptotic cells using a synthetic fluorescent sensor for membrane surfaces that contain phosphatidylserine AV Koulov, KA Stucker, C Lakshmi, JP Robinson, BD Smith Cell Death & Differentiation 10 (12), 1357-1359, 2003 | 120 | 2003 |
| Facilitated transport of sodium or potassium chloride across vesicle membranes using a ditopic salt-binding macrobicycle AV Koulov, JM Mahoney, BD Smith Organic & biomolecular chemistry 1 (1), 27-29, 2003 | 117 | 2003 |
| Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic I g G 1 Molecule E Folzer, K Diepold, K Bomans, C Finkler, R Schmidt, P Bulau, ... Journal of pharmaceutical sciences 104 (9), 2824-2831, 2015 | 112 | 2015 |
| Mouse models for assessing protein immunogenicity: lessons and challenges W Jiskoot, G Kijanka, TW Randolph, JF Carpenter, AV Koulov, HC Mahler, ... Journal of pharmaceutical sciences 105 (5), 1567-1575, 2016 | 108 | 2016 |
| Chemical and biological folding contribute to temperature‐sensitive ΔF508 CFTR trafficking X Wang, AV Koulov, WA Kellner, JR Riordan, WE Balch Traffic 9 (11), 1878-1893, 2008 | 108 | 2008 |
| Considerations for the use of polysorbates in biopharmaceuticals MT Jones, HC Mahler, S Yadav, D Bindra, V Corvari, RM Fesinmeyer, ... Pharmaceutical Research 35, 1-8, 2018 | 107 | 2018 |
| A fluorescent assay for chloride transport; identification of a synthetic anionophore with improved activity BA McNally, AV Koulov, BD Smith, JB Joos, AP Davis Chemical communications, 1087-1089, 2005 | 104 | 2005 |
| Subvisible (2-100 μm) particle analysis during biotherapeutic drug product development: part 1, considerations and strategy LO Narhi, V Corvari, DC Ripple, N Afonina, I Cecchini, MR Defelippis, ... Journal of pharmaceutical sciences 104 (6), 1899-1908, 2015 | 88 | 2015 |
| In Vivo Stability of Therapeutic Proteins J Schuster, A Koulov, HC Mahler, P Detampel, J Huwyler, S Singh, ... Pharmaceutical research 37, 1-17, 2020 | 80 | 2020 |
Hanns-Christian Mahlerapl Prof, Pharmazeutische Technologie, Universität Frankfurt/MVerified email at lonza.com