High-resolution crystal structure of the human CB1 cannabinoid receptor Z Shao, J Yin, K Chapman, M Grzemska, L Clark, J Wang, ... Nature 540 (7634), 602-606, 2016 | 451 | 2016 |
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ... Nature Structural & Molecular Biology 23 (4), 293-299, 2016 | 157 | 2016 |
Ligand modulation of sidechain dynamics in a wild-type human GPCR LD Clark, I Dikiy, K Chapman, KEJ Rödström, J Aramini, MV LeVine, ... Elife 6, e28505, 2017 | 89 | 2017 |
Lipid dynamics and protein–lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1 MT Eddy, TC Ong, L Clark, O Teijido, PCA van der Wel, R Garces, ... Journal of the American Chemical Society 134 (14), 6375-6387, 2012 | 82 | 2012 |
Mechanism of membrane-curvature generation by ER-tubule shaping proteins N Wang, LD Clark, Y Gao, MM Kozlov, T Shemesh, TA Rapoport Nature communications 12 (1), 568, 2021 | 73 | 2021 |
Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris L Clark, JA Zahm, R Ali, M Kukula, L Bian, SM Patrie, KH Gardner, ... Journal of biomolecular NMR 62, 239-245, 2015 | 54 | 2015 |
Crystal structure of the human NK1 tachykinin receptor J Yin, K Chapman, LD Clark, Z Shao, D Borek, Q Xu, J Wang, ... Proceedings of the National Academy of Sciences 115 (52), 13264-13269, 2018 | 49 | 2018 |
Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR MT Eddy, Y Su, R Silvers, L Andreas, L Clark, G Wagner, G Pintacuda, ... Journal of biomolecular NMR 61, 299-310, 2015 | 44 | 2015 |
On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies L Clark, I Dikiy, DM Rosenbaum, KH Gardner Journal of biomolecular NMR 71, 203-211, 2018 | 42 | 2018 |
Magic angle spinning nuclear magnetic resonance characterization of voltage-dependent anion channel gating in two-dimensional lipid crystalline bilayers MT Eddy, L Andreas, O Teijido, Y Su, L Clark, SY Noskov, G Wagner, ... Biochemistry 54 (4), 994-1005, 2015 | 40 | 2015 |
Direct demonstration that loop1 of Scap binds to loop7: a crucial event in cholesterol homeostasis Y Zhang, KM Lee, LN Kinch, L Clark, NV Grishin, DM Rosenbaum, ... Journal of Biological Chemistry 291 (24), 12888-12896, 2016 | 26 | 2016 |
Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing DL Kober, A Radhakrishnan, JL Goldstein, MS Brown, LD Clark, X Bai, ... Cell 184 (14), 3689-3701. e22, 2021 | 25 | 2021 |
Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris R Ali, LD Clark, JA Zahm, A Lemoff, K Ramesh, DM Rosenbaum, ... Journal of biomolecular NMR 73, 687-697, 2019 | 12 | 2019 |
Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson’s disease T Logan, L Clark, SS Ray Biochemistry 49 (27), 5624-5633, 2010 | 12 | 2010 |
Isotopic labeling of eukaryotic membrane proteins for NMR studies of interactions and dynamics I Dikiy, LD Clark, KH Gardner, DM Rosenbaum Methods in enzymology 614, 37-65, 2019 | 10 | 2019 |
CA, Garces, R., Wagner, G., Rostovtseva, TK, and Griffin, RG (2012) Lipid Dynamics and Protein-Lipid Interactions in 2D Crystals Formed with the β-barrel Integral Membrane … MT Eddy, TC Ong, L Clark, O Teijido, P Van Der Wel J. Am. Chem. Soc 134, 6375-6387, 0 | 5 | |
Structural Studies of Integral Membrane Proteins Involved in GPCR Signaling and Sterol Homeostasis LD Clark | | 2018 |
Ligand Modulation of Sidechain Dynamics in a Wild-Type Human GPCR LD Clark, I Dikiy, K Chapman, KE Rodstrom, J Aramini, MV LeVine, ... Biophysical Journal 114 (3), 239a, 2018 | | 2018 |
Magic angle NMR studies of bacterioshodopsin (bR) and the volage depndent anion channel (VDAC) Q Ni, T Can, M Eddy, Y Su, R Silvers, L Andreas, L Clark, G Pintacuda, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
Erratum to: Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris L Clark, JA Zahm, R Ali, M Kukula, L Bian, SM Patrie, KH Gardner, ... Journal of biomolecular NMR 64, 267-267, 2016 | | 2016 |