Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells JH Park, S Adoro, T Guinter, B Erman, AS Alag, M Catalfamo, MY Kimura, ... Nature immunology 11 (3), 257-264, 2010 | 304 | 2010 |
Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals X Tai, B Erman, A Alag, J Mu, M Kimura, G Katz, T Guinter, T McCaughtry, ... Immunity 38 (6), 1116-1128, 2013 | 269 | 2013 |
Identification of a Conserved GATA3 Response Element Upstream Proximal from the Interleukin-13 Gene Locus* 210 M Yamashita, M Ukai-Tadenuma, M Kimura, M Omori, M Inami, ... Journal of Biological Chemistry 277 (44), 42399-42408, 2002 | 238 | 2002 |
T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation M Yamashita, M Kimura, M Kubo, C Shimizu, T Tada, RM Perlmutter, ... Proceedings of the National Academy of Sciences 96 (3), 1024-1029, 1999 | 238 | 1999 |
Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci M Yamashita, M Ukai-Tadenuma, T Miyamoto, K Sugaya, H Hosokawa, ... Journal of Biological Chemistry 279 (26), 26983-26990, 2004 | 217 | 2004 |
Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Vα14 natural killer T cells J Cui, N Watanabe, T Kawano, M Yamashita, T Kamata, C Shimizu, ... The Journal of experimental medicine 190 (6), 783-792, 1999 | 213 | 1999 |
Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function YI Nigo, M Yamashita, K Hirahara, R Shinnakasu, M Inami, M Kimura, ... Proceedings of the National Academy of Sciences 103 (7), 2286-2291, 2006 | 208 | 2006 |
Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway M Yamashita, R Shinnakasu, H Asou, M Kimura, A Hasegawa, ... Journal of Biological Chemistry 280 (33), 29409-29419, 2005 | 202 | 2005 |
IL-7 signaling must be intermittent, not continuous, during CD8+ T cell homeostasis to promote cell survival instead of cell death MY Kimura, LA Pobezinsky, TI Guinter, J Thomas, A Adams, JH Park, ... Nature immunology 14 (2), 143-151, 2013 | 168 | 2013 |
Crucial role of MLL for the maintenance of memory T helper type 2 cell responses M Yamashita, K Hirahara, R Shinnakasu, H Hosokawa, S Norikane, ... Immunity 24 (5), 611-622, 2006 | 168 | 2006 |
Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function LA Pobezinsky, R Etzensperger, S Jeurling, A Alag, T Kadakia, ... Nature immunology 16 (5), 517-524, 2015 | 165 | 2015 |
T cell receptor–induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex M Yamashita, M Katsumata, M Iwashima, M Kimura, C Shimizu, T Kamata, ... The Journal of experimental medicine 191 (11), 1869-1880, 2000 | 146 | 2000 |
The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression T Nakayama, DJ Kasprowicz, M Yamashita, LA Schubert, G Gillard, ... The Journal of Immunology 168 (1), 87-94, 2002 | 138 | 2002 |
src homology 2 domain–containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation T Kamata, M Yamashita, M Kimura, K Murata, M Inami, C Shimizu, ... The Journal of clinical investigation 111 (1), 109-119, 2003 | 136 | 2003 |
Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene M Kimura, Y Koseki, M Yamashita, N Watanabe, C Shimizu, T Katsumoto, ... Immunity 15 (2), 275-287, 2001 | 134 | 2001 |
Lck availability during thymic selection determines the recognition specificity of the T cell repertoire F Van Laethem, AN Tikhonova, LA Pobezinsky, X Tai, MY Kimura, ... Cell 154 (6), 1326-1341, 2013 | 123 | 2013 |
CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA M Omori, M Yamashita, M Inami, M Ukai-Tadenuma, M Kimura, Y Nigo, ... Immunity 19 (2), 281-294, 2003 | 104 | 2003 |
Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-infiltrating T cells Y Mita, MY Kimura, K Hayashizaki, R Koyama-Nasu, T Ito, S Motohashi, ... International immunology 30 (12), 559-567, 2018 | 103 | 2018 |
Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity C Shimizu, H Kawamoto, M Yamashita, M Kimura, E Kondou, Y Kaneko, ... International immunology 13 (1), 105-117, 2001 | 101 | 2001 |
CD69‐null mice protected from arthritis induced with anti‐type II collagen antibodies K Murata, M Inami, A Hasegawa, S Kubo, M Kimura, M Yamashita, ... International immunology 15 (8), 987-992, 2003 | 95 | 2003 |