Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody–drug conjugate (ADC) JPM Nunes, M Morais, V Vassileva, E Robinson, VS Rajkumar, ... Chemical Communications 51 (53), 10624-10627, 2015 | 143 | 2015 |
Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis M Morais, JPM Nunes, K Karu, N Forte, I Benni, MEB Smith, S Caddick, ... Organic & Biomolecular Chemistry 15 (14), 2947-2952, 2017 | 91 | 2017 |
Site-specific chelator-antibody conjugation for PET and SPECT imaging with radiometals M Morais, MT Ma Drug Discovery Today: Technologies 30, 91-104, 2018 | 74 | 2018 |
A platform for efficient, thiol-stable conjugation to albumin's native single accessible cysteine MEB Smith, MB Caspersen, E Robinson, M Morais, A Maruani, ... Organic & Biomolecular Chemistry 13 (29), 7946-7949, 2015 | 74 | 2015 |
Tuning the hydrolytic stability of next generation maleimide cross-linkers enables access to albumin-antibody fragment conjugates and tri-scFvs N Forte, M Livanos, E Miranda, M Morais, X Yang, VS Rajkumar, ... Bioconjugate Chemistry 29 (2), 486-492, 2018 | 67 | 2018 |
Use of a next generation maleimide in combination with THIOMAB™ antibody technology delivers a highly stable, potent and near homogeneous THIOMAB™ antibody-drug conjugate (TDC) JPM Nunes, V Vassileva, E Robinson, M Morais, MEB Smith, RB Pedley, ... RSC advances 7 (40), 24828-24832, 2017 | 63 | 2017 |
New 99mTc(CO)3 Mannosylated Dextran Bearing S-Derivatized Cysteine Chelator for Sentinel Lymph Node Detection I Pirmettis, Y Arano, T Tsotakos, K Okada, A Yamaguchi, T Uehara, ... Molecular pharmaceutics 9 (6), 1681-1692, 2012 | 57 | 2012 |
Mannosylated Dextran Derivatives Labeled with fac-[M(CO)3]+ (M = 99mTc, Re) for Specific Targeting of Sentinel Lymph Node M Morais, S Subramanian, U Pandey, G Samuel, M Venkatesh, M Martins, ... Molecular pharmaceutics 8 (2), 609-620, 2011 | 51 | 2011 |
Target-specific Tc (CO) 3-complexes for in vivo imaging M Morais, A Paulo, L Gano, I Santos, JDG Correia Journal of Organometallic Chemistry 744, 125-139, 2013 | 48 | 2013 |
Novel peptides derived from Dengue virus capsid protein translocate reversibly the blood–brain barrier through a receptor-free mechanism V Neves, F Aires-da-Silva, M Morais, L Gano, E Ribeiro, A Pinto, S Aguiar, ... ACS Chemical Biology 12 (5), 1257-1268, 2017 | 47 | 2017 |
Influence of the Bifunctional Chelator on the Pharmacokinetic Properties of 99mTc(CO)3-Labeled Cyclic α-Melanocyte Stimulating Hormone Analog M Morais, BL Oliveira, JDG Correia, MC Oliveira, MA Jiménez, I Santos, ... Journal of medicinal chemistry 56 (5), 1961-1973, 2013 | 40 | 2013 |
Evaluation of novel 99mTc(I)-labeled homobivalent α-melanocyte-stimulating hormone analogs for melanocortin-1 receptor targeting M Morais, PD Raposinho, MC Oliveira, JDG Correia, I Santos JBIC Journal of Biological Inorganic Chemistry 17, 491-505, 2012 | 26 | 2012 |
Radiolabeled mannosylated dextran derivatives bearing an NIR-fluorophore for sentinel lymph node imaging M Morais, MPC Campello, C Xavier, J Heemskerk, JDG Correia, ... Bioconjugate chemistry 25 (11), 1963-1970, 2014 | 22 | 2014 |
Biodistribution of a 67Ga-labeled anti-TNF VHH single-domain antibody containing a bacterial albumin-binding domain (Zag) M Morais, C Cantante, L Gano, I Santos, S Lourenço, C Santos, C Fontes, ... Nuclear medicine and biology 41, e44-e48, 2014 | 21 | 2014 |
Albumin-binding domain from Streptococcus zooepidemicus protein Zag as a novel strategy to improve the half-life of therapeutic proteins C Cantante, S Lourenço, M Morais, J Leandro, L Gano, N Silva, ... Journal of biotechnology 253, 23-33, 2017 | 19 | 2017 |
Application of next-generation maleimides (NGMs) to site-selective antibody conjugation M Morais, N Forte, V Chudasama, JR Baker Bioconjugation: Methods and Protocols, 15-24, 2019 | 13 | 2019 |
NMR Structural Analysis of MC1R-Targeted Rhenium(I) Metallopeptides and Biological Evaluation of 99mTc(I) Congeners M Morais, PD Raposinho, MC Oliveira, D Pantoja-Uceda, MA Jiménez, ... Organometallics 31 (16), 5929-5939, 2012 | 13 | 2012 |
Nonconventional trans‐Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity Studies MA Medrano, M Morais, VFC Ferreira, JDG Correia, A Paulo, I Santos, ... European Journal of Inorganic Chemistry 2017 (12), 1835-1840, 2017 | 12 | 2017 |
Re (I) and Tc (I) complexes for targeting nitric oxide synthase: Influence of the chelator in the affinity for the enzyme BL Oliveira, M Morais, F Mendes, IS Moreira, C Cordeiro, PA Fernandes, ... Chemical biology & drug design 86 (5), 1072-1086, 2015 | 9 | 2015 |
Aires da Silva, F.; Goncalves, J.; Correia, JD Biodistribution of a (67) Ga-labeled anti-TNF VHH single-domain antibody containing a bacterial albumin-binding domain (Zag) M Morais, C Cantante, L Gano, I Santos, S Lourenço, C Santos, C Fontes Nucl. Med. Biol 41, e44-e48, 2014 | 8 | 2014 |