| High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism JE Griffin, JD Gawronski, MA DeJesus, TR Ioerger, BJ Akerley, ... PLoS pathogens 7 (9), e1002251, 2011 | 1179 | 2011 |
| Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long, CC Boutte, EJ Rubin, ... MBio 8 (1), 10.1128/mbio. 02133-16, 2017 | 608 | 2017 |
| TRANSIT-a software tool for Himar1 TnSeq analysis MA DeJesus, C Ambadipudi, R Baker, C Sassetti, TR Ioerger PLoS computational biology 11 (10), e1004401, 2015 | 223 | 2015 |
| Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis B Bosch, MA DeJesus, NC Poulton, W Zhang, CA Engelhart, A Zaveri, ... Cell 184 (17), 4579-4592. e24, 2021 | 200 | 2021 |
| CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis S Li, NC Poulton, JS Chang, ZA Azadian, MA DeJesus, N Ruecker, ... Nature microbiology 7 (6), 766-779, 2022 | 112 | 2022 |
| Chemical genetic interaction profiling reveals determinants of intrinsic antibiotic resistance in Mycobacterium tuberculosis W Xu, MA DeJesus, N Rücker, CA Engelhart, MG Wright, C Healy, K Lin, ... Antimicrobial agents and chemotherapy 61 (12), 10.1128/aac. 01334-17, 2017 | 108 | 2017 |
| A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data MA DeJesus, TR Ioerger BMC bioinformatics 14, 1-12, 2013 | 99 | 2013 |
| Identifying Essential Genes in Mycobacterium tuberculosis by Global Phenotypic Profiling JE Long, M DeJesus, D Ward, RE Baker, T Ioerger, CM Sassetti Gene Essentiality: Methods and Protocols, 79-95, 2015 | 98 | 2015 |
| Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries MA DeJesus, YJ Zhang, CM Sassetti, EJ Rubin, JC Sacchettini, ... Bioinformatics 29 (6), 695-703, 2013 | 94 | 2013 |
| Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction CA Orsini, B Setlow, M DeJesus, S Galaviz, K Loesch, T Ioerger, D Wallis Molecular genetics & genomic medicine 4 (3), 322-343, 2016 | 60 | 2016 |
| Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice J Korte, M Alber, CM Trujillo, K Syson, H Koliwer-Brandl, R Deenen, ... PLoS pathogens 12 (12), e1006043, 2016 | 47 | 2016 |
| Statistical analysis of genetic interactions in Tn-Seq data MA DeJesus, S Nambi, CM Smith, RE Baker, CM Sassetti, TR Ioerger Nucleic acids research 45 (11), e93-e93, 2017 | 43 | 2017 |
| Reannotation of translational start sites in the genome of Mycobacterium tuberculosis MA DeJesus, JC Sacchettini, TR Ioerger Tuberculosis 93 (1), 18-25, 2013 | 39 | 2013 |
| Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression S Subramaniyam, MA DeJesus, A Zaveri, CM Smith, RE Baker, S Ehrt, ... BMC bioinformatics 20, 1-15, 2019 | 23 | 2019 |
| CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to … GH Babunovic, MA DeJesus, B Bosch, MR Chase, T Barbier, AK Dickey, ... MBio 13 (1), e03683-21, 2022 | 22 | 2022 |
| Normalization of transposon-mutant library sequencing datasets to improve identification of conditionally essential genes MA DeJesus, TR Ioerger Journal of bioinformatics and computational biology 14 (03), 1642004, 2016 | 19 | 2016 |
| Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis NC Poulton, ZA Azadian, MA DeJesus, JM Rock Antimicrobial Agents and Chemotherapy 66 (9), e00904-22, 2022 | 18 | 2022 |
| Beyond antibiotic resistance: the whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria NC Poulton, MA DeJesus, V Munsamy-Govender, M Kanai, CG Roberts, ... Cell Chemical Biology 31 (4), 669-682. e7, 2024 | 11 | 2024 |
| Compensatory evolution in NusG improves fitness of drug-resistant M. tuberculosis KA Eckartt, M Delbeau, V Munsamy-Govender, MA DeJesus, ZA Azadian, ... Nature 628 (8006), 186-194, 2024 | 10 | 2024 |
| The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality A Jinich, A Zaveri, MA DeJesus, E Flores-Bautista, CM Smith, CM Sassetti, ... bioRxiv, 2021.03. 05.434127, 2021 | 10 | 2021 |
Thomas R IoergerProfessor of Computer Science, Texas A&M UniversityVerified email at cs.tamu.edu
