Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway V Lallemand-Breitenbach, M Jeanne, S Benhenda, R Nasr, M Lei, ... Nature cell biology 10 (5), 547-555, 2008 | 833 | 2008 |
Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation R Nasr, MC Guillemin, O Ferhi, H Soilihi, L Peres, C Berthier, P Rousselot, ... Nature medicine 14 (12), 1333-1342, 2008 | 454 | 2008 |
MicroRNAs as biomarkers for early breast cancer diagnosis, prognosis and therapy prediction FJ Nassar, R Nasr, R Talhouk Pharmacology & therapeutics 172, 34-49, 2017 | 219 | 2017 |
Arsenic Trioxide and Interferon- Synergize to Induce Cell Cycle Arrest and Apoptosis in Human T-Cell Lymphotropic Virus Type I–Transformed Cells A Bazarbachi, ME El-Sabban, R Nasr, F Quignon, C Awaraji, J Kersual, ... Blood, The Journal of the American Society of Hematology 93 (1), 278-283, 1999 | 208 | 1999 |
Arsenic-interferon-α–triggered apoptosis in HTLV-I transformed cells is associated with Tax down-regulation and reversal of NF-κB activation ME El-Sabban, R Nasr, G Dbaibo, O Hermine, N Abboushi, F Quignon, ... Blood, The Journal of the American Society of Hematology 96 (8), 2849-2855, 2000 | 181 | 2000 |
New therapeutic approaches for adult T-cell leukaemia A Bazarbachi, D Ghez, Y Lepelletier, R Nasr, ME El-Sabban, O Hermine The lancet oncology 5 (11), 664-672, 2004 | 160 | 2004 |
Therapy-induced PML/RARA Proteolysis and Acute Promyelocytic Leukemia Cure R Nasr, V Lallemand-Breitenbach, J Zhu, MC Guillemin, H de Thé Clinical Cancer Research 15 (20), 6321-6326, 2009 | 142 | 2009 |
Gut microbiome: a promising biomarker for immunotherapy in colorectal cancer S Temraz, F Nassar, R Nasr, M Charafeddine, D Mukherji, ... International journal of molecular sciences 20 (17), 4155, 2019 | 127 | 2019 |
RXR is an essential component of the oncogenic PML/RARA complex in vivo J Zhu, R Nasr, L Pérès, F Riaucoux-Lormière, N Honoré, C Berthier, ... Cancer cell 12 (1), 23-35, 2007 | 127 | 2007 |
Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-κB activation R Nasr, E Chiari, M El-Sabban, R Mahieux, Y Kfoury, M Abdulhay, ... Blood 107 (10), 4021-4029, 2006 | 126 | 2006 |
Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1–infected leukemic cells R Nasr, A Rosenwald, ME El-Sabban, B Arnulf, P Zalloua, Y Lepelletier, ... Blood 101 (11), 4576-4582, 2003 | 124 | 2003 |
Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia H El Hajj, M El-Sabban, H Hasegawa, G Zaatari, J Ablain, ST Saab, ... Journal of Experimental Medicine 207 (13), 2785-2792, 2010 | 104 | 2010 |
Exosomal non coding RNA in LIQUID biopsies as a promising biomarker for colorectal cancer A Baassiri, F Nassar, D Mukherji, A Shamseddine, R Nasr, S Temraz International journal of molecular sciences 21 (4), 1398, 2020 | 93 | 2020 |
Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome Y Kfoury, R Nasr, A Favre-Bonvin, M El-Sabban, N Renault, ML Giron, ... Oncogene 27 (12), 1665-1676, 2008 | 91 | 2008 |
Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma R Nasr, ME El-Sabban, JA Karam, G Dbaibo, Y Kfoury, B Arnulf, ... Oncogene 24 (3), 419-430, 2005 | 89 | 2005 |
The crosstalk between microbiome and immune response in gastric cancer R Nasr, A Shamseddine, D Mukherji, F Nassar, S Temraz International journal of molecular sciences 21 (18), 6586, 2020 | 83 | 2020 |
Human T-cell lymphotropic virus type I-infected cells extravasate through the endothelial barrier by a local angiogenesis-like mechanism A Bazarbachi, RA Merhi, A Gessain, R Talhouk, H El-Khoury, R Nasr, ... Cancer research 64 (6), 2039-2046, 2004 | 73 | 2004 |
Emerging therapeutic strategies for targeting chronic myeloid leukemia stem cells A Hamad, Z Sahli, M El Sabban, M Mouteirik, R Nasr Stem cells international 2013 (1), 724360, 2013 | 72 | 2013 |
(+) α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo GAS Dos Santos, RS Abreu e Lima, CR Pestana, ASG Lima, ... Leukemia 26 (3), 451-460, 2012 | 71 | 2012 |
Evidence against a direct cytotoxic effect of alpha interferon and zidovudine in HTLV-I associated adult T cell leukemia/lymphoma A Bazarbachi, R Nasr, ME El-Sabban, A Mahe, R Mahieux, A Gessain, ... Leukemia 14 (4), 716-721, 2000 | 69 | 2000 |