| General performance of density functionals SF Sousa, PA Fernandes, MJ Ramos The Journal of Physical Chemistry A 111 (42), 10439-10452, 2007 | 1409 | 2007 |
| Protein–ligand docking: current status and future challenges SF Sousa, PA Fernandes, MJ Ramos Proteins: structure, function, and bioinformatics 65 (1), 15-26, 2006 | 1394 | 2006 |
| Hot spots—A review of the protein–protein interface determinant amino‐acid residues IS Moreira, PA Fernandes, MJ Ramos Proteins: Structure, Function, and Bioinformatics 68 (4), 803-812, 2007 | 953 | 2007 |
| Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza JF Bermejo-Martin, R Ortiz de Lejarazu, T Pumarola, J Rello, R Almansa, ... Critical care 13, 1-11, 2009 | 749 | 2009 |
| α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure–activity relationship study C Proença, M Freitas, D Ribeiro, EFT Oliveira, JLC Sousa, SM Tomé, ... Journal of enzyme inhibition and medicinal chemistry 32 (1), 1216-1228, 2017 | 452 | 2017 |
| The adaptive evolution of the mammalian mitochondrial genome RR Da Fonseca, WE Johnson, SJ O'Brien, MJ Ramos, A Antunes BMC genomics 9, 1-22, 2008 | 443 | 2008 |
| Cholesterol biosynthesis: a mechanistic overview NM Cerqueira, EF Oliveira, DS Gesto, D Santos-Martins, C Moreira, ... Biochemistry 55 (39), 5483-5506, 2016 | 383 | 2016 |
| Protein-ligand docking in the new millennium–a retrospective of 10 years in the field SF Sousa, AJM Ribeiro, JTS Coimbra, RPP Neves, SA Martins, N Moorthy, ... Current medicinal chemistry 20 (18), 2296-2314, 2013 | 302 | 2013 |
| Computational alanine scanning mutagenesis—an improved methodological approach IS Moreira, PA Fernandes, MJ Ramos Journal of computational chemistry 28 (3), 644-654, 2007 | 285 | 2007 |
| AutoDock4Zn: An Improved AutoDock Force Field for Small-Molecule Docking to Zinc Metalloproteins D Santos-Martins, S Forli, MJ Ramos, AJ Olson Journal of chemical information and modeling 54 (8), 2371-2379, 2014 | 273 | 2014 |
| Theoretical insights into the mechanism for thiol/disulfide exchange PA Fernandes, MJ Ramos Chemistry–A European Journal 10 (1), 257-266, 2004 | 232 | 2004 |
| Understanding ribonucleotide reductase inactivation by gemcitabine NM Cerqueira, PA Fernandes, MJ Ramos Chemistry–A European Journal 13 (30), 8507-8515, 2007 | 217 | 2007 |
| The chemistry of snake venom and its medicinal potential AL Oliveira, MF Viegas, SL da Silva, AM Soares, MJ Ramos, ... Nature Reviews Chemistry 6 (7), 451-469, 2022 | 198 | 2022 |
| Application of quantum mechanics/molecular mechanics methods in the study of enzymatic reaction mechanisms SF Sousa, AJM Ribeiro, RPP Neves, NF Brás, NM Cerqueira, ... Wiley Interdisciplinary Reviews: Computational Molecular Science 7 (2), e1281, 2017 | 194 | 2017 |
| Computational enzymatic catalysis MJ Ramos, PA Fernandes Accounts of chemical research 41 (6), 689-698, 2008 | 183 | 2008 |
| NF-κB in human disease: current inhibitors and prospects for de novo structure based design of inhibitors V Pande, MJ Ramos Current medicinal chemistry 12 (3), 357-374, 2005 | 182 | 2005 |
| Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure–activity relationship C Proença, M Freitas, D Ribeiro, SM Tomé, EFT Oliveira, MF Viegas, ... Journal of enzyme inhibition and medicinal chemistry 34 (1), 577-588, 2019 | 171 | 2019 |
| Protein–protein docking dealing with the unknown IS Moreira, PA Fernandes, MJ Ramos Journal of computational chemistry 31 (2), 317-342, 2010 | 170 | 2010 |
| The carboxylate shift in zinc enzymes: A computational study SF Sousa, PA Fernandes, MJ Ramos Journal of the American Chemical Society 129 (5), 1378-1385, 2007 | 164 | 2007 |
| Vascular endothelial growth factor (VEGF) inhibition-a critical review I Sousa Moreira, P Alexandrino Fernandes, M Joao Ramos Anti-cancer agents in medicinal chemistry (formerly current medicinal …, 2007 | 161 | 2007 |
Pedro A. FernandesProfessor of Chemistry and Biochemistry, University of Porto, PortugalVerified email at fc.up.pt