A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo F Abulwerdi, C Liao, M Liu, AS Azmi, A Aboukameel, ASA Mady, ... Molecular cancer therapeutics 13 (3), 565-575, 2014 | 221 | 2014 |
Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1 FA Abulwerdi, W Xu, AA Ageeli, MJ Yonkunas, G Arun, H Nam, ... ACS chemical biology 14 (2), 223-235, 2019 | 170 | 2019 |
Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA FA Abulwerdi, MD Shortridge, J Sztuba-Solinska, R Wilson, SFJ Le Grice, ... Journal of Medicinal Chemistry 59 (24), 11148-11160, 2016 | 103 | 2016 |
3-Substituted-N-(4-hydroxynaphthalen-1-yl) arylsulfonamides as a novel class of selective Mcl-1 inhibitors: structure-based design, synthesis, SAR, and biological evaluation FA Abulwerdi, C Liao, AS Mady, J Gavin, C Shen, T Cierpicki, JA Stuckey, ... Journal of medicinal chemistry 57 (10), 4111-4133, 2014 | 99 | 2014 |
Isomerization in fluorescent protein chromophores involves addition/elimination J Dong, F Abulwerdi, A Baldridge, J Kowalik, KM Solntsev, LM Tolbert Journal of the American Chemical Society 130 (43), 14096-14098, 2008 | 79 | 2008 |
Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition L Chen, W Chen, M Mysliwski, J Serio, J Ropa, FA Abulwerdi, RJ Chan, ... Leukemia 29 (6), 1290-1300, 2015 | 69 | 2015 |
Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays CM Connelly, FA Abulwerdi, JS Schneekloth Small Molecule Microarrays, 157-175, 2017 | 45 | 2017 |
Targeting mcl-1 for radiosensitization of pancreatic cancers D Wei, Q Zhang, JS Schreiber, LA Parsels, FA Abulwerdi, T Kausar, ... Translational oncology 8 (1), 47-54, 2015 | 40 | 2015 |
Discovery and Characterization of 2, 5-Substituted Benzoic Acid Dual Inhibitors of the Anti-Apoptotic Mcl-1 and Bfl-1 Proteins KJ Kump, L Miao, ASA Mady, NH Ansari, UK Shrestha, Y Yang, M Pal, ... Journal of Medicinal Chemistry, 2020 | 33 | 2020 |
Microarray-based technologies for the discovery of selective, RNA-binding molecules FA Abulwerdi, JS Schneekloth Jr Methods 103, 188-195, 2016 | 29 | 2016 |
Recent Advances in Targeting the HIV-1 Tat/TAR Complex FA Abulwerdi, SFJ Le Grice Current pharmaceutical design 23 (28), 4112-4121, 2017 | 20 | 2017 |
Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening ASA Mady, C Liao, N Bajwa, KJ Kump, FA Abulwerdi, KL Lev, L Miao, ... Scientific reports 8 (1), 1-15, 2018 | 18 | 2018 |
BH3 profiling reveals selectivity by herpesviruses for specific Bcl-2 proteins to mediate survival of latently infected cells O Cojohari, CM Burrer, MA Peppenelli, FA Abulwerdi, ... Journal of virology 89 (10), 5739-5746, 2015 | 11 | 2015 |
Small molecule inhibitors of Mcl-1 and the uses of thereof Z Nikolovska-Coleska, HD Showalter, C Liao, R Mohammad, F Abulwerdi US Patent 9,486,422, 2016 | 7 | 2016 |
Mcl-1 small-molecule inhibitors encapsulated into nanoparticles exhibit increased killing efficacy towards HCMV-infected monocytes CM Burrer, H Auburn, X Wang, J Luo, FA Abulwerdi, ... Antiviral Research 138, 40-46, 2017 | 6 | 2017 |
Small molecule inhibitors of MCL-1 and uses thereof Z Nikolovska-Coleska, F Abulwerdi, H Showalter, L Miao, J Stuckey, ... US Patent 9,394,303, 2016 | 4 | 2016 |
Structure-Based Design, Synthesis and Evaluation of Novel and Selective Small-Molecule Inhibitors of the Anti-Apoptotic Protein Mcl-1. FA Abulwerdi | | 2014 |