Pi-Pi contacts are an overlooked protein feature relevant to phase separation RMC Vernon, PA Chong, B Tsang, TH Kim, A Bah, P Farber, H Lin, ... elife 7, e31486, 2018 | 754 | 2018 |
Structural basis of Smad2 recognition by the Smad anchor for receptor activation G Wu, YG Chen, B Ozdamar, CA Gyuricza, PA Chong, JL Wrana, ... Science 287 (5450), 92-97, 2000 | 445 | 2000 |
RGG/RG motif regions in RNA binding and phase separation PA Chong, RM Vernon, JD Forman-Kay Journal of molecular biology 430 (23), 4650-4665, 2018 | 362 | 2018 |
Liquid–liquid phase separation in cellular signaling systems PA Chong, JD Forman-Kay Current opinion in structural biology 41, 180-186, 2016 | 224 | 2016 |
Direct binding of the corrector VX-809 to human CFTR NBD1: evidence of an allosteric coupling between the binding site and the NBD1: CL4 interface RP Hudson, JE Dawson, PA Chong, Z Yang, L Millen, PJ Thomas, ... Molecular pharmacology 92 (2), 124-135, 2017 | 101 | 2017 |
Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity PA Chong, H Lin, JL Wrana, JD Forman-Kay Proceedings of the National Academy of Sciences 107 (43), 18404-18409, 2010 | 99 | 2010 |
Characterization of the PilN, PilO and PilP type IVa pilus subcomplex S Tammam, LM Sampaleanu, J Koo, P Sundaram, M Ayers, ... Molecular microbiology 82 (6), 1496-1514, 2011 | 85 | 2011 |
An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2 PA Chong, H Lin, JL Wrana, JD Forman-Kay Journal of Biological Chemistry 281 (25), 17069-17075, 2006 | 82 | 2006 |
Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions Z Bozoky, M Krzeminski, PA Chong, JD Forman‐Kay The FEBS journal 280 (18), 4407-4416, 2013 | 67 | 2013 |
FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation N Birsa, AM Ule, MG Garone, B Tsang, F Mattedi, PA Chong, J Humphrey, ... Science Advances 7 (30), eabf8660, 2021 | 57 | 2021 |
Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator RP Hudson, PA Chong, II Protasevich, R Vernon, E Noy, H Bihler, JL An, ... Journal of Biological Chemistry 287 (34), 28480-28494, 2012 | 57 | 2012 |
Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p EJ Stollar, B Garcia, PA Chong, A Rath, H Lin, JD Forman-Kay, ... Journal of Biological Chemistry 284 (39), 26918-26927, 2009 | 51 | 2009 |
O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances … ML Nosella, M Tereshchenko, I Pritisanac, PA Chong, JA Toretsky, ... Journal of the American Chemical Society 143 (30), 11520-11534, 2021 | 36 | 2021 |
CFTR structure I Callebaut, PA Chong, JD Forman-Kay Journal of Cystic Fibrosis 17 (2), S5-S8, 2018 | 35 | 2018 |
Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy JD Hall, H Wang, LJ Byrnes, S Shanker, K Wang, IV Efremov, PA Chong, ... Protein Science 25 (2), 360-373, 2016 | 32 | 2016 |
Disorder in a target for the smad2 mad homology 2 domain and its implications for binding and specificity PA Chong, B Ozdamar, JL Wrana, JD Forman-Kay Journal of Biological Chemistry 279 (39), 40707-40714, 2004 | 31 | 2004 |
Interplay of buried histidine protonation and protein stability in prion misfolding A Malevanets, PA Chong, DF Hansen, P Rizk, Y Sun, H Lin, ... Scientific reports 7 (1), 882, 2017 | 29 | 2017 |
Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits … PA Chong, PJ Farber, RM Vernon, RP Hudson, AK Mittermaier, ... Journal of Biological Chemistry 290 (38), 22862-22878, 2015 | 27 | 2015 |
Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability PA Chong, P Kota, NV Dokholyan, JD Forman-Kay Cold Spring Harbor perspectives in medicine 3 (3), a009522, 2013 | 27 | 2013 |
Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition JE Dawson, A Bah, Z Zhang, RM Vernon, H Lin, PA Chong, M Vanama, ... Nature Communications 11 (1), 3146, 2020 | 26 | 2020 |