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P Andrew Chong
P Andrew Chong
Unknown affiliation
Verified email at sickkids.ca
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Cited by
Cited by
Year
Pi-Pi contacts are an overlooked protein feature relevant to phase separation
RMC Vernon, PA Chong, B Tsang, TH Kim, A Bah, P Farber, H Lin, ...
elife 7, e31486, 2018
7542018
Structural basis of Smad2 recognition by the Smad anchor for receptor activation
G Wu, YG Chen, B Ozdamar, CA Gyuricza, PA Chong, JL Wrana, ...
Science 287 (5450), 92-97, 2000
4452000
RGG/RG motif regions in RNA binding and phase separation
PA Chong, RM Vernon, JD Forman-Kay
Journal of molecular biology 430 (23), 4650-4665, 2018
3622018
Liquid–liquid phase separation in cellular signaling systems
PA Chong, JD Forman-Kay
Current opinion in structural biology 41, 180-186, 2016
2242016
Direct binding of the corrector VX-809 to human CFTR NBD1: evidence of an allosteric coupling between the binding site and the NBD1: CL4 interface
RP Hudson, JE Dawson, PA Chong, Z Yang, L Millen, PJ Thomas, ...
Molecular pharmacology 92 (2), 124-135, 2017
1012017
Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity
PA Chong, H Lin, JL Wrana, JD Forman-Kay
Proceedings of the National Academy of Sciences 107 (43), 18404-18409, 2010
992010
Characterization of the PilN, PilO and PilP type IVa pilus subcomplex
S Tammam, LM Sampaleanu, J Koo, P Sundaram, M Ayers, ...
Molecular microbiology 82 (6), 1496-1514, 2011
852011
An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2
PA Chong, H Lin, JL Wrana, JD Forman-Kay
Journal of Biological Chemistry 281 (25), 17069-17075, 2006
822006
Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions
Z Bozoky, M Krzeminski, PA Chong, JD Forman‐Kay
The FEBS journal 280 (18), 4407-4416, 2013
672013
FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation
N Birsa, AM Ule, MG Garone, B Tsang, F Mattedi, PA Chong, J Humphrey, ...
Science Advances 7 (30), eabf8660, 2021
572021
Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator
RP Hudson, PA Chong, II Protasevich, R Vernon, E Noy, H Bihler, JL An, ...
Journal of Biological Chemistry 287 (34), 28480-28494, 2012
572012
Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p
EJ Stollar, B Garcia, PA Chong, A Rath, H Lin, JD Forman-Kay, ...
Journal of Biological Chemistry 284 (39), 26918-26927, 2009
512009
O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances …
ML Nosella, M Tereshchenko, I Pritisanac, PA Chong, JA Toretsky, ...
Journal of the American Chemical Society 143 (30), 11520-11534, 2021
362021
CFTR structure
I Callebaut, PA Chong, JD Forman-Kay
Journal of Cystic Fibrosis 17 (2), S5-S8, 2018
352018
Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy
JD Hall, H Wang, LJ Byrnes, S Shanker, K Wang, IV Efremov, PA Chong, ...
Protein Science 25 (2), 360-373, 2016
322016
Disorder in a target for the smad2 mad homology 2 domain and its implications for binding and specificity
PA Chong, B Ozdamar, JL Wrana, JD Forman-Kay
Journal of Biological Chemistry 279 (39), 40707-40714, 2004
312004
Interplay of buried histidine protonation and protein stability in prion misfolding
A Malevanets, PA Chong, DF Hansen, P Rizk, Y Sun, H Lin, ...
Scientific reports 7 (1), 882, 2017
292017
Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits …
PA Chong, PJ Farber, RM Vernon, RP Hudson, AK Mittermaier, ...
Journal of Biological Chemistry 290 (38), 22862-22878, 2015
272015
Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability
PA Chong, P Kota, NV Dokholyan, JD Forman-Kay
Cold Spring Harbor perspectives in medicine 3 (3), a009522, 2013
272013
Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition
JE Dawson, A Bah, Z Zhang, RM Vernon, H Lin, PA Chong, M Vanama, ...
Nature Communications 11 (1), 3146, 2020
262020
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