| Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers SJ Lam, NM O'Brien-Simpson, N Pantarat, A Sulistio, EHH Wong, ... Nature microbiology 1 (11), 1-11, 2016 | 769 | 2016 |
| Porphyromonas gingivalis Outer Membrane Vesicles Exclusively Contain Outer Membrane and Periplasmic Proteins and Carry a Cargo Enriched with Virulence … PD Veith, YY Chen, DG Gorasia, D Chen, MD Glew, NM O’Brien-Simpson, ... Journal of proteome research 13 (5), 2420-2432, 2014 | 276 | 2014 |
| Engineering highly effective antimicrobial selenium nanoparticles through control of particle size T Huang, JA Holden, DE Heath, NM O'Brien-Simpson, AJ O'Connor Nanoscale 11 (31), 14937-14951, 2019 | 207 | 2019 |
| Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo JD Cecil, NM O’Brien-Simpson, JC Lenzo, JA Holden, W Singleton, ... Frontiers in immunology 8, 1017, 2017 | 170 | 2017 |
| Macrophage depletion abates Porphyromonas gingivalis–induced alveolar bone resorption in mice RS Lam, NM O’Brien-Simpson, JC Lenzo, JA Holden, GC Brammar, ... The Journal of Immunology 193 (5), 2349-2362, 2014 | 165 | 2014 |
| Spatially resolved force spectroscopy of bacterial surfaces using force-volume imaging F Gaboriaud, BS Parcha, ML Gee, JA Holden, RA Strugnell Colloids and Surfaces B: Biointerfaces 62 (2), 206-213, 2008 | 137 | 2008 |
| The Multi-Copper-Ion Oxidase CueO of Salmonella enterica Serovar Typhimurium Is Required for Systemic Virulence MES Achard, JJ Tree, JA Holden, KR Simpfendorfer, OLC Wijburg, ... Infection and immunity 78 (5), 2312-2319, 2010 | 131 | 2010 |
| Porphyromonas gingivalis lipopolysaccharide weakly activates M1 and M2 polarized mouse macrophages but induces inflammatory cytokines JA Holden, TJ Attard, KM Laughton, A Mansell, NM O'Brien-Simpson, ... Infection and immunity 82 (10), 4190-4203, 2014 | 130 | 2014 |
| Tumor associated macrophages: origin, recruitment, phenotypic diversity, and targeting T Hourani, JA Holden, W Li, JC Lenzo, S Hadjigol, NM O’Brien-Simpson Frontiers in Oncology 11, 788365, 2021 | 126 | 2021 |
| Differential responses of pattern recognition receptors to outer membrane vesicles of three periodontal pathogens JD Cecil, NM O’Brien-Simpson, JC Lenzo, JA Holden, YY Chen, ... PLoS One 11 (4), e0151967, 2016 | 116 | 2016 |
| Unprimed, M1 and M2 Macrophages Differentially Interact with Porphyromonas gingivalis RS Lam, NM O’Brien-Simpson, JA Holden, JC Lenzo, SB Fong, ... PloS one 11 (7), e0158629, 2016 | 105 | 2016 |
| Multifunctional antimicrobial polypeptide-selenium nanoparticles combat drug-resistant bacteria T Huang, JA Holden, EC Reynolds, DE Heath, NM O’Brien-Simpson, ... ACS Applied Materials & Interfaces 12 (50), 55696-55709, 2020 | 70 | 2020 |
| Architectural effects of star‐shaped “structurally nanoengineered antimicrobial peptide polymers”(SNAPPs) on their biological activity SJ Shirbin, I Insua, JA Holden, JC Lenzo, EC Reynolds, ... Advanced Healthcare Materials 7 (21), 1800627, 2018 | 61 | 2018 |
| Enhancing proline-rich antimicrobial peptide action by homodimerization: Influence of bifunctional linker W Li, F Lin, A Hung, A Barlow, MA Sani, R Paolini, W Singleton, J Holden, ... Chemical Science 13 (8), 2226-2237, 2022 | 44 | 2022 |
| Covalent conjugation of cationic antimicrobial peptides with a β‐lactam antibiotic core W Li, NM O'Brien‐Simpson, JA Holden, L Otvos, EC Reynolds, ... Peptide Science 110 (3), e24059, 2018 | 44 | 2018 |
| Tannerella forsythia Outer Membrane Vesicles Are Enriched with Substrates of the Type IX Secretion System and TonB-Dependent Receptors PD Veith, YY Chen, D Chen, NM O’Brien-Simpson, JD Cecil, JA Holden, ... Journal of Proteome Research 14 (12), 5355-5366, 2015 | 42 | 2015 |
| A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis NM O’Brien-Simpson, JA Holden, JC Lenzo, Y Tan, GC Brammar, ... npj Vaccines 1 (1), 1-11, 2016 | 35 | 2016 |
| Gamma Interferon-Independent Effects of Interleukin-12 on Immunity to Salmonella enterica Serovar Typhimurium JD Price, KR Simpfendorfer, RR Mantena, J Holden, WR Heath, ... Infection and immunity 75 (12), 5753-5762, 2007 | 31 | 2007 |
| Determination of active phagocytosis of unopsonized Porphyromonas gingivalis by macrophages and neutrophils using the pH-sensitive fluorescent dye pHrodo JC Lenzo, NM O'Brien-Simpson, J Cecil, JA Holden, EC Reynolds Infection and immunity 84 (6), 1753-1760, 2016 | 29 | 2016 |
| GM‐CSF and uPA are required for Porphyromonas gingivalis‐induced alveolar bone loss in a mouse periodontitis model RS Lam, NM O'Brien‐Simpson, JA Hamilton, JC Lenzo, JA Holden, ... Immunology and Cell Biology 93 (8), 705-715, 2015 | 29 | 2015 |
