Phase-plate cryo-EM structure of a class B GPCR–G-protein complex YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ... Nature 546 (7656), 118-123, 2017 | 511 | 2017 |
Structure of the adenosine-bound human adenosine A1 receptor–Gi complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 344 | 2018 |
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex YL Liang, M Khoshouei, A Glukhova, SGB Furness, P Zhao, L Clydesdale, ... Nature 555 (7694), 121-125, 2018 | 322 | 2018 |
Structural insights into G-protein-coupled receptor allostery DM Thal, A Glukhova, PM Sexton, A Christopoulos Nature 559 (7712), 45-53, 2018 | 305 | 2018 |
Structure of the adenosine A1 receptor reveals the basis for subtype selectivity A Glukhova, DM Thal, AT Nguyen, EA Vecchio, M Jörg, PJ Scammells, ... Cell 168 (5), 867-877. e13, 2017 | 299 | 2017 |
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor YL Liang, M Khoshouei, G Deganutti, A Glukhova, C Koole, TS Peat, ... Nature 561 (7724), 492-497, 2018 | 245 | 2018 |
Differential GLP-1R binding and activation by peptide and non-peptide agonists X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ... Molecular Cell 80 (3), 485-500. e7, 2020 | 153 | 2020 |
Automatic local resolution-based sharpening of cryo-EM maps E Ramírez-Aportela, JL Vilas, A Glukhova, R Melero, P Conesa, ... Bioinformatics 36 (3), 765-772, 2020 | 137 | 2020 |
Activation mechanism of PINK1 ZY Gan, S Callegari, SA Cobbold, TR Cotton, MJ Mlodzianoski, ... Nature 602 (7896), 328-335, 2022 | 130 | 2022 |
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia CJ Draper-Joyce, R Bhola, J Wang, A Bhattarai, ATN Nguyen, ... Nature 597 (7877), 571-576, 2021 | 128 | 2021 |
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice P Pymm, A Adair, LJ Chan, JP Cooney, FL Mordant, CC Allison, E Lopez, ... Proceedings of the National Academy of Sciences 118 (19), e2101918118, 2021 | 126 | 2021 |
Rules of engagement: GPCRs and G proteins A Glukhova, CJ Draper-Joyce, RK Sunahara, A Christopoulos, D Wootten, ... ACS pharmacology & translational science 1 (2), 73-83, 2018 | 120 | 2018 |
Dominant negative G proteins enhance formation and purification of agonist-GPCR-G protein complexes for structure determination YL Liang, P Zhao, C Draper-Joyce, JA Baltos, A Glukhova, TT Truong, ... ACS pharmacology & translational science 1 (1), 12-20, 2018 | 106 | 2018 |
Heterooligomeric complexes formed by human small heat shock proteins HspB1 (Hsp27) and HspB6 (Hsp20) OV Bukach, AE Glukhova, AS Seit-Nebi, NB Gusev Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (3), 486-495, 2009 | 96 | 2009 |
Structure and function of lysosomal phospholipase A2 and lecithin: cholesterol acyltransferase A Glukhova, V Hinkovska-Galcheva, R Kelly, A Abe, JA Shayman, ... Nature communications 6 (1), 6250, 2015 | 92 | 2015 |
Recent advances in the determination of G protein-coupled receptor structures DM Thal, Z Vuckovic, CJ Draper-Joyce, YL Liang, A Glukhova, ... Current opinion in structural biology 51, 28-34, 2018 | 65 | 2018 |
Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor*♦ KT Homan, HV Waldschmidt, A Glukhova, A Cannavo, J Song, ... Journal of Biological Chemistry 290 (34), 20649-20659, 2015 | 57 | 2015 |
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation G Deganutti, YL Liang, X Zhang, M Khoshouei, L Clydesdale, ... Nature Communications 13 (1), 92, 2022 | 55 | 2022 |
Structure and dynamics of the active Gs-coupled human secretin receptor M Dong, G Deganutti, SJ Piper, YL Liang, M Khoshouei, MJ Belousoff, ... Nature communications 11 (1), 4137, 2020 | 55 | 2020 |
Architecture of the Nitric-oxide Synthase Holoenzyme Reveals Large Conformational Changes and a Calmodulin-driven Release of the FMN Domain*♦ AL Yokom, Y Morishima, M Lau, M Su, A Glukhova, Y Osawa, ... Journal of Biological Chemistry 289 (24), 16855-16865, 2014 | 50 | 2014 |