| SC3: consensus clustering of single-cell RNA-seq data VY Kiselev, K Kirschner, MT Schaub, T Andrews, A Yiu, T Chandra, ... Nature methods 14 (5), 483-486, 2017 | 1439 | 2017 |
| Autophagy mediates the mitotic senescence transition ARJ Young, M Narita, M Ferreira, K Kirschner, M Sadaie, JFJ Darot, ... Genes & development 23 (7), 798-803, 2009 | 1217 | 2009 |
| Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis S Alivernini, L MacDonald, A Elmesmari, S Finlay, B Tolusso, MR Gigante, ... Nature medicine 26 (8), 1295-1306, 2020 | 519 | 2020 |
| Global reorganization of the nuclear landscape in senescent cells T Chandra, PA Ewels, S Schoenfelder, M Furlan-Magaril, SW Wingett, ... Cell reports 10 (4), 471-483, 2015 | 352 | 2015 |
| Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation T Chandra, K Kirschner, JY Thuret, BD Pope, T Ryba, S Newman, ... Molecular cell 47 (2), 203-214, 2012 | 317 | 2012 |
| Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress R Burt, A Dey, S Aref, M Aguiar, A Akarca, K Bailey, W Day, S Hooper, ... Blood, The Journal of the American Society of Hematology 134 (17), 1415-1429, 2019 | 208 | 2019 |
| NOTUM from Apc-mutant cells biases clonal competition to initiate cancer DJ Flanagan, N Pentinmikko, K Luopajärvi, NJ Willis, K Gilroy, AP Raven, ... Nature 594 (7863), 430-435, 2021 | 184 | 2021 |
| Multiple roles of the ERCC1-XPF endonuclease in DNA repair and resistance to anticancer drugs K Kirschner, DW Melton Anticancer research 30 (9), 3223-3232, 2010 | 168 | 2010 |
| Experimental design for single-cell RNA sequencing J Baran-Gale, T Chandra, K Kirschner Briefings in functional genomics 17 (4), 233-239, 2018 | 159 | 2018 |
| Notch signaling mediates secondary senescence YV Teo, N Rattanavirotkul, N Olova, A Salzano, A Quintanilla, N Tarrats, ... Cell reports 27 (4), 997-1007. e5, 2019 | 120 | 2019 |
| Amplification of HSD17B1 and ERBB2 in primary breast cancer C Gunnarsson, M Ahnström, K Kirschner, B Olsson, B Nordenskjöld, ... Oncogene 22 (1), 34-40, 2003 | 103 | 2003 |
| Proliferation drives aging-related functional decline in a subpopulation of the hematopoietic stem cell compartment K Kirschner, T Chandra, V Kiselev, D Flores-Santa Cruz, IC Macaulay, ... Cell reports 19 (8), 1503-1511, 2017 | 100 | 2017 |
| Cytokine‐induced megakaryocytic differentiation is regulated by genome‐wide loss of a uSTAT transcriptional program HJ Park, J Li, R Hannah, S Biddie, AI Leal‐Cervantes, K Kirschner, ... The EMBO journal 35 (6), 580-594, 2016 | 95 | 2016 |
| Improving outcomes in chronic myeloid leukemia through harnessing the immunological landscape YC Hsieh, K Kirschner, M Copland Leukemia 35 (5), 1229-1242, 2021 | 91 | 2021 |
| Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion DG Kent, J Li, H Tanna, J Fink, K Kirschner, DC Pask, Y Silber, ... PLoS biology 11 (6), e1001576, 2013 | 88 | 2013 |
| Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects NA Robertson, E Latorre-Crespo, M Terradas-Terradas, J Lemos-Portela, ... Nature medicine 28 (7), 1439-1446, 2022 | 87 | 2022 |
| Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix EJ Kay, K Paterson, C Riera-Domingo, D Sumpton, JHM Däbritz, ... Nature metabolism 4 (6), 693-710, 2022 | 84 | 2022 |
| Latent regulatory potential of human-specific repetitive elements MC Ward, MD Wilson, NL Barbosa-Morais, D Schmidt, R Stark, Q Pan, ... Molecular cell 49 (2), 262-272, 2013 | 79 | 2013 |
| Functional heterogeneity in senescence K Kirschner, N Rattanavirotkul, MF Quince, T Chandra Biochemical Society Transactions 48 (3), 765-773, 2020 | 72 | 2020 |
| Multi-layered spatial transcriptomics identify secretory factors promoting human hematopoietic stem cell development EI Crosse, S Gordon-Keylock, S Rybtsov, A Binagui-Casas, H Felchle, ... Cell Stem Cell 27 (5), 822-839. e8, 2020 | 69 | 2020 |
Wolf ReikHead, Epigenetics Programme, Babraham Institute Cambridge, UKVerified email at babraham.ac.uk