Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis J Riegger, RE Brenner Cell death & disease 10 (10), 683, 2019 | 79 | 2019 |
Pathomechanisms of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious environment J Riegger, RE Brenner International journal of molecular sciences 21 (5), 1560, 2020 | 61 | 2020 |
Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review J Riegger, A Schoppa, L Ruths, M Haffner-Luntzer, A Ignatius Cellular & molecular biology letters 28 (1), 76, 2023 | 59 | 2023 |
Antioxidative therapy in an ex vivo human cartilage trauma-model: attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine J Riegger, H Joos, HG Palm, B Friemert, H Reichel, A Ignatius, ... Osteoarthritis and cartilage 24 (12), 2171-2180, 2016 | 42 | 2016 |
The functional role of chondrogenic stem/progenitor cells: novel evidence for immunomodulatory properties and regenerative potential after cartilage injury J Riegger, HG Palm, RE Brenner Eur Cell Mater 36, 110-127, 2018 | 35 | 2018 |
Extracellular vesicles in musculoskeletal pathologies and regeneration M Herrmann, S Diederichs, S Melnik, J Riegger, D Trivanović, S Li, ... Frontiers in Bioengineering and Biotechnology 8, 624096, 2021 | 34 | 2021 |
Osteoblast lineage Sod2 deficiency leads to an osteoporosis-like phenotype in mice AM Schoppa, X Chen, JM Ramge, A Vikman, V Fischer, ... Disease Models & Mechanisms 15 (5), dmm049392, 2022 | 29 | 2022 |
Striking a new path in reducing cartilage breakdown: combination of antioxidative therapy and chondroanabolic stimulation after blunt cartilage trauma J Riegger, H Joos, HG Palm, B Friemert, H Reichel, A Ignatius, ... Journal of Cellular and Molecular Medicine 22 (1), 77-88, 2018 | 24 | 2018 |
Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma J Riegger, M Huber-Lang, RE Brenner Osteoarthritis and Cartilage 28 (5), 685-697, 2020 | 23 | 2020 |
Terminal complement complex formation is associated with intervertebral disc degeneration GQ Teixeira, Z Yong, RM Goncalves, A Kuhn, J Riegger, H Brisby, ... European Spine Journal 30, 217-226, 2021 | 22 | 2021 |
In vitro characterization of doxorubicin-mediated stress-induced premature senescence in human chondrocytes V Kirsch, JM Ramge, A Schoppa, A Ignatius, J Riegger Cells 11 (7), 1106, 2022 | 20 | 2022 |
Serum cartilage oligomeric matrix protein in late-stage osteoarthritis: association with clinical features, renal function, and cardiovascular biomarkers J Riegger, M Rehm, G Büchele, H Brenner, KP Günther, D Rothenbacher, ... Journal of Clinical Medicine 9 (1), 268, 2020 | 20 | 2020 |
The expression of thrombospondin-4 correlates with disease severity in osteoarthritic knee cartilage K Maly, I Schaible, J Riegger, RE Brenner, A Meurer, F Zaucke International journal of molecular sciences 20 (2), 447, 2019 | 20 | 2019 |
Differential interactive effects of cartilage traumatization and blood exposure in vitro and in vivo H Joos, F Leucht, J Riegger, C Hogrefe, J Fiedler, L Dürselen, H Reichel, ... The American Journal of Sports Medicine 43 (11), 2822-2832, 2015 | 18 | 2015 |
Interleukin-1β and cathepsin D modulate formation of the terminal complement complex in cultured human disc tissue GQ Teixeira, Z Yong, A Kuhn, J Riegger, RM Goncalves, M Ruf, ... European Spine Journal 30 (8), 2247-2256, 2021 | 15 | 2021 |
The hexosamine biosynthetic pathway as a therapeutic target after cartilage trauma: modification of chondrocyte survival and metabolism by glucosamine derivatives and PUGNAc in … J Riegger, J Baumert, F Zaucke, RE Brenner International journal of molecular sciences 22 (14), 7247, 2021 | 15 | 2021 |
Simvastatin and fluvastatin attenuate trauma-induced cell death and catabolism in human cartilage J Riegger, S Maurer, S Pulasani, RE Brenner Frontiers in Bioengineering and Biotechnology 10, 965302, 2022 | 11 | 2022 |
Initial harm reduction by N-acetylcysteine alleviates cartilage degeneration after blunt single-impact cartilage trauma in vivo J Riegger, F Leucht, HG Palm, A Ignatius, RE Brenner International journal of molecular sciences 20 (12), 2916, 2019 | 11 | 2019 |
Hypothermia promotes cell-protective and chondroprotective effects after blunt cartilage trauma J Riegger, M Zimmermann, H Joos, T Kappe, RE Brenner The American Journal of Sports Medicine 46 (2), 420-430, 2018 | 11 | 2018 |
Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes J Riegger, RE Brenner Elife 12, e91453, 2023 | 6 | 2023 |