| Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial S Russell, J Bennett, JA Wellman, DC Chung, ZF Yu, A Tillman, J Wittes, ... The Lancet 390 (10097), 849-860, 2017 | 1825 | 2017 |
| Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ... Cell 154 (2), 452-464, 2013 | 554 | 2013 |
| Unexpected mutations after CRISPR–Cas9 editing in vivo KA Schaefer, WH Wu, DF Colgan, SH Tsang, AG Bassuk, VB Mahajan Nature methods 14 (6), 547-548, 2017 | 482 | 2017 |
| Connectin: a homophilic cell adhesion molecule expressed on a subset of muscles and the motoneurons that innervate them in Drosophila A Nose, VB Mahajan, CS Goodman Cell 70 (4), 553-567, 1992 | 348 | 1992 |
| Automated early detection of diabetic retinopathy MD Abràmoff, JM Reinhardt, SR Russell, JC Folk, VB Mahajan, ... Ophthalmology 117 (6), 1147-1154, 2010 | 336 | 2010 |
| Aflibercept therapy for exudative age-related macular degeneration resistant to bevacizumab and ranibizumab B Bakall, JC Folk, HC Boldt, EH Sohn, EM Stone, SR Russell, ... American journal of ophthalmology 156 (1), 15-22. e1, 2013 | 305 | 2013 |
| Viral delivery systems for CRISPR CL Xu, MZC Ruan, VB Mahajan, SH Tsang Viruses 11 (1), 28, 2019 | 257 | 2019 |
| Opposing T cell responses in experimental autoimmune encephalomyelitis N Saligrama, F Zhao, MJ Sikora, WS Serratelli, RA Fernandes, DM Louis, ... Nature 572 (7770), 481-487, 2019 | 212 | 2019 |
| Precision medicine: genetic repair of retinitis pigmentosa in patient-derived stem cells AG Bassuk, A Zheng, Y Li, SH Tsang, VB Mahajan Scientific reports 6 (1), 19969, 2016 | 208 | 2016 |
| Mutations in prickle orthologs cause seizures in flies, mice, and humans H Tao, JR Manak, L Sowers, X Mei, H Kiyonari, T Abe, NS Dahdaleh, ... The American Journal of Human Genetics 88 (2), 138-149, 2011 | 167 | 2011 |
| Retinal and choroidal angiogenesis: a review of new targets T Cabral, LGM Mello, LH Lima, J Polido, CV Regatieri, R Belfort, ... International journal of retina and vitreous 3, 1-13, 2017 | 156 | 2017 |
| Gene therapy and genome surgery in the retina JE DiCarlo, VB Mahajan, SH Tsang The Journal of clinical investigation 128 (6), 2177-2188, 2018 | 141 | 2018 |
| CRISPR repair reveals causative mutation in a preclinical model of retinitis pigmentosa WH Wu, YT Tsai, S Justus, TT Lee, L Zhang, CS Lin, AG Bassuk, ... Molecular Therapy 24 (8), 1388-1394, 2016 | 127 | 2016 |
| Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome RE McIntyre, P Lakshminarasimhan Chavali, O Ismail, DM Carragher, ... PLoS genetics 8 (11), e1003022, 2012 | 103 | 2012 |
| Proteomic insight into the molecular function of the vitreous JM Skeie, CN Roybal, VB Mahajan PloS one 10 (5), e0127567, 2015 | 102 | 2015 |
| Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton VB Mahajan, KS Pai, A Lau, DD Cunningham Proceedings of the National Academy of Sciences 97 (22), 12062-12067, 2000 | 99 | 2000 |
| Calpain-5 mutations cause autoimmune uveitis, retinal neovascularization, and photoreceptor degeneration VB Mahajan, JM Skeie, AG Bassuk, JH Fingert, TA Braun, HT Daggett, ... Public Library of Science 8 (10), e1003001, 2012 | 98 | 2012 |
| HTRA 1, an age‐related macular degeneration protease, processes extracellular matrix proteins EFEMP 1 and TSP 1 MK Lin, J Yang, CW Hsu, A Gore, AG Bassuk, LM Brown, R Colligan, ... Aging cell 17 (4), e12710, 2018 | 97 | 2018 |
| Intravitreal bevacizumab during pregnancy RM Tarantola, JC Folk, HC Boldt, VB Mahajan Retina 30 (9), 1405-1411, 2010 | 97 | 2010 |
| Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration L Zhang, J Du, S Justus, CW Hsu, L Bonet-Ponce, WH Wu, YT Tsai, ... The Journal of clinical investigation 126 (12), 4659-4673, 2016 | 96 | 2016 |
Stephen H. TsangColumbia UniversityVerified email at columbia.edu