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Seiya Oura
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Engineered CRISPR-Cas9 nuclease with expanded targeting space
H Nishimasu, X Shi, S Ishiguro, L Gao, S Hirano, S Okazaki, T Noda, ...
Science 361 (6408), 1259-1262, 2018
11152018
Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm− oocyte fusion in mice
T Noda, Y Lu, Y Fujihara, S Oura, T Koyano, S Kobayashi, MM Matzuk, ...
Proceedings of the National Academy of Sciences 117 (21), 11493-11502, 2020
1342020
CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice
Y Lu, S Oura, T Matsumura, A Oji, N Sakurai, Y Fujihara, K Shimada, ...
Biology of Reproduction 101 (2), 501-511, 2019
1052019
Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids
L Liu, S Oura, Z Markham, JN Hamilton, RM Skory, L Li, M Sakurai, ...
Cell 186 (18), 3776-3792. e16, 2023
732023
Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice
Y Fujihara, T Noda, K Kobayashi, A Oji, S Kobayashi, T Matsumura, ...
Proceedings of the National Academy of Sciences 116 (37), 18498-18506, 2019
642019
Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk
L Yu, D Logsdon, CA Pinzon-Arteaga, J Duan, T Ezashi, Y Wei, AER Orsi, ...
Cell Stem Cell 30 (9), 1246-1261. e9, 2023
572023
ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility
K Shimada, S Park, H Miyata, Z Yu, A Morohoshi, S Oura, MM Matzuk, ...
Proceedings of the National Academy of Sciences 118 (6), e2018355118, 2021
552021
SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice
H Miyata, S Oura, A Morohoshi, K Shimada, D Mashiko, Y Oyama, ...
Proceedings of the National Academy of Sciences 118 (35), e2106673118, 2021
452021
The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility
RJ Holcomb, S Oura, K Nozawa, K Kent, Z Yu, MJ Robertson, C Coarfa, ...
Biology of Reproduction 102 (1), 84-91, 2020
422020
Testis‐enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa
H Miyata, K Shimada, A Morohoshi, S Oura, T Matsumura, Z Xu, Y Oyama, ...
The FASEB Journal 34 (4), 5389-5400, 2020
392020
Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish
T Noda, A Blaha, Y Fujihara, KR Gert, C Emori, VE Deneke, S Oura, ...
Communications Biology 5 (1), 332, 2022
312022
PHF7 modulates BRDT stability and histone-to-protamine exchange during spermiogenesis
CR Kim, T Noda, H Kim, G Kim, S Park, Y Na, S Oura, K Shimada, I Bang, ...
Cell reports 32 (4), 2020
302020
FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice
A Morohoshi, H Miyata, Y Oyama, S Oura, T Noda, M Ikawa
Development 148 (21), dev199644, 2021
272021
KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice
S Oura, T Koyano, C Kodera, Y Horisawa-Takada, M Matsuyama, ...
PLoS genetics 17 (5), e1009412, 2021
262021
Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity
T Noda, Y Fujihara, T Matsumura, S Oura, S Kobayashi, M Ikawa
Biology of Reproduction 100 (4), 1035-1045, 2019
262019
Cfap97d1 is important for flagellar axoneme maintenance and male mouse fertility
S Oura, S Kazi, A Savolainen, K Nozawa, J Castaneda, Z Yu, H Miyata, ...
PLoS genetics 16 (8), e1008954, 2020
242020
Precise CAG repeat contraction in a Huntington’s Disease mouse model is enabled by gene editing with SpCas9-NG
S Oura, T Noda, N Morimura, S Hitoshi, H Nishimasu, Y Nagai, O Nureki, ...
Communications Biology 4 (1), 771, 2021
232021
TESMIN, METALLOTHIONEIN-LIKE 5, is required for spermatogenesis in mice
A Oji, A Isotani, Y Fujihara, JM Castaneda, S Oura, M Ikawa
Biology of reproduction 102 (4), 975-983, 2020
212020
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility
D Kiyozumi, K Shimada, M Chalick, C Emori, M Kodani, S Oura, T Noda, ...
Nature Communications 14 (1), 2354, 2023
182023
Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice
S Oura, H Miyata, T Noda, K Shimada, T Matsumura, A Morohoshi, ...
Experimental animals 68 (1), 25-34, 2019
172019
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