| Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma RWK Chiu, KCA Chan, Y Gao, VYM Lau, W Zheng, TY Leung, CHF Foo, ... Proceedings of the National Academy of Sciences 105 (51), 20458-20463, 2008 | 1495 | 2008 |
| Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus YMD Lo, KCA Chan, H Sun, EZ Chen, P Jiang, FMF Lun, YW Zheng, ... Science translational medicine 2 (61), 61ra91-61ra91, 2010 | 1462 | 2010 |
| Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study RWK Chiu, R Akolekar, YWL Zheng, TY Leung, H Sun, KCA Chan, ... Bmj 342, 2011 | 1159 | 2011 |
| Size distributions of maternal and fetal DNA in maternal plasma KCA Chan, J Zhang, ABY Hui, N Wong, TK Lau, TN Leung, KW Lo, ... Clinical chemistry 50 (1), 88-92, 2004 | 966 | 2004 |
| Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection IFN Hung, KKW To, CK Lee, KL Lee, K Chan, WW Yan, R Liu, CL Watt, ... Clinical Infectious Diseases 52 (4), 447-456, 2011 | 879 | 2011 |
| Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments K Sun, P Jiang, KCA Chan, J Wong, YKY Cheng, RHS Liang, W Chan, ... Proceedings of the National Academy of Sciences 112 (40), E5503-E5512, 2015 | 773 | 2015 |
| Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients P Jiang, CWM Chan, KCA Chan, SH Cheng, J Wong, VWS Wong, ... Proceedings of the National Academy of Sciences 112 (11), E1317-E1325, 2015 | 758 | 2015 |
| Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients N Lee, KCA Chan, DS Hui, EKO Ng, A Wu, RWK Chiu, VWS Wong, ... Journal of clinical virology 31 (4), 304-309, 2004 | 741 | 2004 |
| Analysis of plasma Epstein–Barr virus DNA to screen for nasopharyngeal cancer KCA Chan, JKS Woo, A King, BCY Zee, WKJ Lam, SL Chan, SWI Chu, ... New England Journal of Medicine 377 (6), 513-522, 2017 | 726 | 2017 |
| Digital PCR for the molecular detection of fetal chromosomal aneuploidy YMD Lo, FMF Lun, KCA Chan, NBY Tsui, KC Chong, TK Lau, TY Leung, ... Proceedings of the National Academy of Sciences 104 (32), 13116-13121, 2007 | 710 | 2007 |
| Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma FMF Lun, RWK Chiu, KC Allen Chan, T Yeung Leung, T Kin Lau, ... Clinical chemistry 54 (10), 1664-1672, 2008 | 684 | 2008 |
| Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing KCA Chan, P Jiang, YWL Zheng, GJW Liao, H Sun, J Wong, SSN Siu, ... Clinical chemistry 59 (1), 211-224, 2013 | 630 | 2013 |
| Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma FMF Lun, NBY Tsui, KCA Chan, TY Leung, TK Lau, P Charoenkwan, ... Proceedings of the National Academy of Sciences 105 (50), 19920-19925, 2008 | 557 | 2008 |
| Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non–small cell lung cancer patients TKF Yung, KCA Chan, TSK Mok, J Tong, KF To, YMD Lo Clinical Cancer Research 15 (6), 2076-2084, 2009 | 554 | 2009 |
| Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing KCA Chan, P Jiang, CWM Chan, K Sun, J Wong, EP Hui, SL Chan, ... Proceedings of the National Academy of Sciences 110 (47), 18761-18768, 2013 | 509 | 2013 |
| Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing EZ Chen, RWK Chiu, H Sun, R Akolekar, KCA Chan, TY Leung, P Jiang, ... PloS one 6 (7), e21791, 2011 | 504 | 2011 |
| Hypermethylated RASSF1A in Maternal Plasma: A Universal Fetal DNA Marker that Improves the Reliability of Noninvasive Prenatal Diagnosis KCA Chan, C Ding, A Gerovassili, SW Yeung, RWK Chiu, TN Leung, ... Clinical chemistry 52 (12), 2211-2218, 2006 | 489 | 2006 |
| Antitumor activity of nivolumab in recurrent and metastatic nasopharyngeal carcinoma: an international, multicenter study of the mayo clinic phase 2 consortium (NCI-9742) BBY Ma, WT Lim, BC Goh, EP Hui, KW Lo, A Pettinger, NR Foster, ... Journal of Clinical Oncology 36 (14), 1412-1418, 2018 | 433 | 2018 |
| Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma S Leung, B Zee, BB Ma, EP Hui, F Mo, M Lai, KCA Chan, LYS Chan, ... Journal of clinical oncology 24 (34), 5414-5418, 2006 | 406 | 2006 |
| Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing SCY Yu, KCA Chan, YWL Zheng, P Jiang, GJW Liao, H Sun, R Akolekar, ... Proceedings of the National Academy of Sciences 111 (23), 8583-8588, 2014 | 357 | 2014 |
