Immunogenicity of therapeutic protein aggregates EM Moussa, JP Panchal, BS Moorthy, JS Blum, MK Joubert, LO Narhi, ... Journal of pharmaceutical sciences 105 (2), 417-430, 2016 | 558 | 2016 |
The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host–parasite interaction AP Jackson, TD Otto, A Darby, A Ramaprasad, D Xia, IE Echaide, ... Nucleic acids research 42 (11), 7113-7131, 2014 | 113 | 2014 |
Predictive models of lyophilization process for development, scale-up/tech transfer and manufacturing T Zhu, EM Moussa, M Witting, D Zhou, K Sinha, M Hirth, M Gastens, ... European Journal of Pharmaceutics and Biopharmaceutics 128, 363-378, 2018 | 55 | 2018 |
Foslevodopa/foscarbidopa: a new subcutaneous treatment for Parkinson's disease M Rosebraugh, EA Voight, EM Moussa, F Jameel, X Lou, GGZ Zhang, ... Annals of neurology 90 (1), 52-61, 2021 | 54 | 2021 |
Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel … A Ramaprasad, T Mourier, R Naeem, TB Malas, E Moussa, A Panigrahi, ... Plos one 10 (4), e0124473, 2015 | 38 | 2015 |
Effects of drying process on an IgG1 monoclonal antibody using solid-state hydrogen deuterium exchange with mass spectrometric analysis (ssHDX-MS) EM Moussa, NE Wilson, QT Zhou, SK Singh, S Nema, EM Topp Pharmaceutical research 35, 1-12, 2018 | 36 | 2018 |
Interleukin-10 Regulates Hepcidin in Plasmodium falciparum Malaria H Huang, AA Lamikanra, MS Alkaitis, ML Thézénas, A Ramaprasad, ... PloS one 9 (2), e88408, 2014 | 34 | 2014 |
Physical Characterization and Innate Immunogenicity of Aggregated Intravenous Immunoglobulin (IGIV) in an In Vitro Cell-Based Model EM Moussa, J Kotarek, JS Blum, E Marszal, EM Topp Pharmaceutical Research 33, 1736-1751, 2016 | 29 | 2016 |
Recommended best practices for lyophilization validation—2021 part I: process design and modeling F Jameel, A Alexeenko, A Bhambhani, G Sacha, T Zhu, S Tchessalov, ... AAPS PharmSciTech 22 (7), 221, 2021 | 22 | 2021 |
Proteomic profiling of the plasma of Gambian children with cerebral malaria EM Moussa, H Huang, ML Thézénas, R Fischer, A Ramaprasad, ... Malaria Journal 17, 1-8, 2018 | 21 | 2018 |
Probing the conformation of an IgG1 monoclonal antibody in lyophilized solids using solid-state hydrogen–deuterium exchange with mass spectrometric analysis (ssHDX-MS) EM Moussa, SK Singh, M Kimmel, S Nema, EM Topp Molecular Pharmaceutics 15 (2), 356-368, 2018 | 19 | 2018 |
Recommended best practices for lyophilization validation 2021 part II: process qualification and continued process verification F Jameel, A Alexeenko, A Bhambhani, G Sacha, T Zhu, S Tchessalov, ... AAPS PharmSciTech 22, 1-25, 2021 | 16 | 2021 |
Structure of monoclonal antibodies BS Moorthy, B Xie, EM Moussa, LK Iyer, S Chandrasekhar, JP Panchal, ... Biobetters: Protein Engineering to Approach the Curative, 81-89, 2015 | 14 | 2015 |
End-to-end approach to surfactant selection, risk mitigation, and control strategies for protein-based therapeutics AM Morales, A Sreedhara, J Buecheler, S Brosig, D Chou, T Christian, ... The AAPS journal 25 (1), 6, 2022 | 10 | 2022 |
Accelerated storage for shelf-life prediction of lyophiles: temperature dependence of degradation of amorphous small molecular weight drugs and proteins E Shalaev, S Ohtake, EM Moussa, J Searles, S Nail, CJ Roberts Journal of Pharmaceutical Sciences 112 (6), 1509-1522, 2023 | 9 | 2023 |
Chapter 1: monoclonal antibodies: structure, physicochemical stability, and protein engineering BJ Mills, EM Moussa, F Jameel Development of Biopharmaceutical Drug-Device Products, 3-26, 2020 | 8 | 2020 |
Proteomic profiling of the brain of mice with experimental cerebral malaria E Moussa, H Huang, M Ahras, A Lall, ML Thezenas, R Fischer, ... Journal of proteomics 180, 61-69, 2018 | 6 | 2018 |
Chapter 21: Rational Design of a Freeze-Drying Process for Protein Products F Jameel, T Zhu, EM Moussa, BJ Mills Development of Biopharmaceutical Drug-Device Products, 499-537, 2020 | 5 | 2020 |
In-situ molecular vapor composition measurements during Lyophilization ET Liechty, AD Strongrich, EM Moussa, E Topp, AA Alexeenko Pharmaceutical Research 35, 1-10, 2018 | 4 | 2018 |
Chapter 16: Development of robust lyophilization process for therapeutic proteins: a case study EM Moussa, T Zhu, F Jameel Development of biopharmaceutical drug-device products, 391-403, 2020 | 3 | 2020 |