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Jacob F Wardman
Jacob F Wardman
Postdoctoral Fellow, AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Carbohydrate-active enzymes (CAZymes) in the gut microbiome
JF Wardman*, RK Bains*, P Rahfeld, SG Withers
Nature Reviews Microbiology 20 (9), 542-556, 2022
3202022
Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the Salvia divinorum clerodienyl diphosphate synthase
KA Pelot, R Mitchell, M Kwon, LM Hagelthorn, JF Wardman, A Chiang, ...
The Plant Journal 89 (5), 885-897, 2017
692017
Prospecting for microbial α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase
P Rahfeld*, JF Wardman*, K Mehr, D Huff, C Morgan-Lang, HM Chen, ...
Journal of Biological Chemistry 294 (44), 16400-16415, 2019
332019
A synthetic gene library yields a previously unknown glycoside phosphorylase that degrades and assembles poly-β-1, 3-GlcNAc, completing the suite of β-linked GlcNAc polysaccharides
SS Macdonald, JH Pereira, F Liu, G Tegl, A DeGiovanni, JF Wardman, ...
ACS Central Science 8 (4), 430-440, 2022
122022
Synthesis and evaluation of sensitive coumarin-based fluorogenic substrates for discovery of α-N-acetyl galactosaminidases through droplet-based screening
HM Chen, SA Nasseri, P Rahfeld, JF Wardman, M Kohsiek, SG Withers
Organic & Biomolecular Chemistry 19 (4), 789-793, 2021
122021
Discovery and development of promiscuous O-glycan hydrolases for removal of intact sialyl T-antigen
JF Wardman, P Rahfeld, F Liu, C Morgan-Lang, L Sim, SJ Hallam, ...
ACS Chemical Biology 16 (10), 2004-2015, 2021
82021
A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins
JF Wardman, L Sim, J Liu, TA Howard, A Geissner, PM Danby, ...
Nature Chemical Biology 19 (10), 1246-1255, 2023
62023
Characterization of a new family of 6-sulfo-N-acetylglucosaminidases
RK Bains, SA Nasseri, F Liu, JF Wardman, P Rahfeld, SG Withers
Journal of Biological Chemistry 299 (10), 2023
52023
Advances in the understanding and exploitation of carbohydrate-active enzymes
RK Bains*, SA Nasseri*, JF Wardman*, SG Withers
Current Opinion in Chemical Biology 80, 102457, 2024
22024
Ultrahigh-Throughput Single Emulsion Droplet Screening for the Discovery of New B Antigen Cleaving Enzymes
C Olagnon, JF Wardman, F Liu, HM Chen, H Moon, SA Nasseri, D Seale, ...
ACS Catalysis 14 (17), 12884-12894, 2024
2024
Carbohydrate-active enzyme (CAZyme) Discovery and Engineering via (Ultra) High-throughput Screening
JF Wardman, SG Withers
RSC Chemical Biology, 2024
2024
Vinyl Halide‐Modified Unsaturated Cyclitols are Mechanism‐Based Glycosidase Inhibitors
PM Danby, A Jeong, L Sim, RP Sweeney, JF Wardman, R Karimi, ...
Angewandte Chemie 135 (21), e202301258, 2023
2023
Discovery and engineering of enzymes for the manipulation of glycoproteins
JF Wardman
University of British Columbia, 2023
2023
Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the Salvia divinorum clerodienyl diphosphate synthase.
KA Pelot, R Mitchell, M Kwon, LM Hagelthorn, JF Wardman, A Chiang, ...
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