Carbohydrate-active enzymes (CAZymes) in the gut microbiome JF Wardman*, RK Bains*, P Rahfeld, SG Withers Nature Reviews Microbiology 20 (9), 542-556, 2022 | 320 | 2022 |
Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the Salvia divinorum clerodienyl diphosphate synthase KA Pelot, R Mitchell, M Kwon, LM Hagelthorn, JF Wardman, A Chiang, ... The Plant Journal 89 (5), 885-897, 2017 | 69 | 2017 |
Prospecting for microbial α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase P Rahfeld*, JF Wardman*, K Mehr, D Huff, C Morgan-Lang, HM Chen, ... Journal of Biological Chemistry 294 (44), 16400-16415, 2019 | 33 | 2019 |
A synthetic gene library yields a previously unknown glycoside phosphorylase that degrades and assembles poly-β-1, 3-GlcNAc, completing the suite of β-linked GlcNAc polysaccharides SS Macdonald, JH Pereira, F Liu, G Tegl, A DeGiovanni, JF Wardman, ... ACS Central Science 8 (4), 430-440, 2022 | 12 | 2022 |
Synthesis and evaluation of sensitive coumarin-based fluorogenic substrates for discovery of α-N-acetyl galactosaminidases through droplet-based screening HM Chen, SA Nasseri, P Rahfeld, JF Wardman, M Kohsiek, SG Withers Organic & Biomolecular Chemistry 19 (4), 789-793, 2021 | 12 | 2021 |
Discovery and development of promiscuous O-glycan hydrolases for removal of intact sialyl T-antigen JF Wardman, P Rahfeld, F Liu, C Morgan-Lang, L Sim, SJ Hallam, ... ACS Chemical Biology 16 (10), 2004-2015, 2021 | 8 | 2021 |
A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins JF Wardman, L Sim, J Liu, TA Howard, A Geissner, PM Danby, ... Nature Chemical Biology 19 (10), 1246-1255, 2023 | 6 | 2023 |
Characterization of a new family of 6-sulfo-N-acetylglucosaminidases RK Bains, SA Nasseri, F Liu, JF Wardman, P Rahfeld, SG Withers Journal of Biological Chemistry 299 (10), 2023 | 5 | 2023 |
Advances in the understanding and exploitation of carbohydrate-active enzymes RK Bains*, SA Nasseri*, JF Wardman*, SG Withers Current Opinion in Chemical Biology 80, 102457, 2024 | 2 | 2024 |
Ultrahigh-Throughput Single Emulsion Droplet Screening for the Discovery of New B Antigen Cleaving Enzymes C Olagnon, JF Wardman, F Liu, HM Chen, H Moon, SA Nasseri, D Seale, ... ACS Catalysis 14 (17), 12884-12894, 2024 | | 2024 |
Carbohydrate-active enzyme (CAZyme) Discovery and Engineering via (Ultra) High-throughput Screening JF Wardman, SG Withers RSC Chemical Biology, 2024 | | 2024 |
Vinyl Halide‐Modified Unsaturated Cyclitols are Mechanism‐Based Glycosidase Inhibitors PM Danby, A Jeong, L Sim, RP Sweeney, JF Wardman, R Karimi, ... Angewandte Chemie 135 (21), e202301258, 2023 | | 2023 |
Discovery and engineering of enzymes for the manipulation of glycoproteins JF Wardman University of British Columbia, 2023 | | 2023 |
Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the Salvia divinorum clerodienyl diphosphate synthase. KA Pelot, R Mitchell, M Kwon, LM Hagelthorn, JF Wardman, A Chiang, ... | | |