| Drug combination therapy increases successful drug repositioning W Sun, PE Sanderson, W Zheng Drug discovery today 21 (7), 1189-1195, 2016 | 443 | 2016 |
| The phenyldimethylsilyl group as a masked hydroxy group I Fleming, R Henning, DC Parker, HE Plaut, PEJ Sanderson Journal of the Chemical Society, Perkin Transactions 1, 317-337, 1995 | 317 | 1995 |
| A one-pot conversion of the phenyldimethylsilyl group into a hydroxyl group I Fleming, PEJ Sanderson Tetrahedron letters 28 (36), 4229-4232, 1987 | 307 | 1987 |
| Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs J Kouznetsova, W Sun, C Martínez-Romero, G Tawa, P Shinn, CZ Chen, ... Emerging microbes & infections 3 (1), 1-7, 2014 | 264 | 2014 |
| The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S, 4S)-4-methyl-1-(pyrimidin-2-ylmethyl) pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1, 5-dihydro-4H … PH Hutson, EN Finger, BC Magliaro, SM Smith, A Converso, ... Neuropharmacology 61 (4), 665-676, 2011 | 161 | 2011 |
| An enzymatic TMPRSS2 assay for assessment of clinical candidates and discovery of inhibitors as potential treatment of COVID-19 JH Shrimp, SC Kales, PE Sanderson, A Simeonov, M Shen, MD Hall ACS pharmacology & translational science 3 (5), 997-1007, 2020 | 135 | 2020 |
| Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines CS Burgey, KA Robinson, TA Lyle, PEJ Sanderson, SD Lewis, BJ Lucas, ... Journal of medicinal chemistry 46 (4), 461-473, 2003 | 135 | 2003 |
| Small, noncovalent serine protease inhibitors PEJ Sanderson Medicinal research reviews 19 (2), 179-197, 1999 | 135 | 1999 |
| Efficacious, orally bioavailable thrombin inhibitors based on 3-aminopyridinone or 3-aminopyrazinone acetamide peptidomimetic templates PEJ Sanderson, TA Lyle, KJ Cutrona, DL Dyer, BD Dorsey, ... Journal of medicinal chemistry 41 (23), 4466-4474, 1998 | 125 | 1998 |
| Synergistic drug combination effectively blocks Ebola virus infection W Sun, S He, C Martínez-Romero, J Kouznetsova, G Tawa, M Xu, P Shinn, ... Antiviral research 137, 165-172, 2017 | 109 | 2017 |
| Thrombin inhibitor design PEJ Sanderson, AM Naylor-Olsen Current medicinal chemistry 5 (4), 289-304, 1998 | 105 | 1998 |
| Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria W Sun, RA Weingarten, M Xu, N Southall, S Dai, P Shinn, PE Sanderson, ... Emerging microbes & infections 5 (1), 1-11, 2016 | 95 | 2016 |
| An allosteric Akt inhibitor effectively blocks Akt signaling and tumor growth with only transient effects on glucose and insulin levels in vivo C Cherrin, K Haskell, B Howell, R Jones, K Leander, R Robinson, ... Cancer biology & therapy 9 (7), 493-503, 2010 | 70 | 2010 |
| L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor PEJ Sanderson, KJ Cutrona, BD Dorsey, DL Dyer, CM McDonough, ... Bioorganic & medicinal chemistry letters 8 (7), 817-822, 1998 | 69 | 1998 |
| Inhibitors of HIV reverse transcriptase TM Williams, TM Ciccarone, WS Saari, JS Wai, WJ Greenlee, SK Balani, ... US Patent 5,527,819, 1996 | 68 | 1996 |
| Potent, orally bioavailable somatostatin agonists: good absorption achieved by urea backbone cyclization A Pasternak, Y Pan, D Marino, PE Sanderson, R Mosley, SP Rohrer, ... Bioorganic & medicinal chemistry letters 9 (3), 491-496, 1999 | 61 | 1999 |
| Pyrazinone thrombin inhibitors PE Sanderson, TA Lyle, BD Dorsey, RJ Varsolona US Patent 5,866,573, 1999 | 58 | 1999 |
| Enantioselective complexation of simple amides by a C2 host molecule PEJ Sanderson, JD Kilburn, WC Still Journal of the American Chemical Society 111 (21), 8314-8315, 1989 | 58 | 1989 |
| Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva E Williams, J Bagarova, G Kerr, DD Xia, ES Place, D Dey, Y Shen, ... Jci Insight 6 (8), 2021 | 57 | 2021 |
| Pyridinone thrombin inhibitors PE Sanderson, AM Naylor-Olsen, DL Dyer, JP Vacca, RCA Isaacs, ... US Patent 5,668,289, 1997 | 55 | 1997 |
