The origin of NMDA receptor hypofunction in schizophrenia K Nakazawa, K Sapkota Pharmacology & therapeutics 205, 107426, 2020 | 252 | 2020 |
Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure–Activity Relationships and Mechanisms of Action ES Burnell, M Irvine, G Fang, K Sapkota, DE Jane, DT Monaghan Journal of medicinal chemistry 62 (1), 3-23, 2018 | 69 | 2018 |
GluN2D N-methyl-d-aspartate receptor subunit contribution to the stimulation of brain activity and gamma oscillations by ketamine: implications for schizophrenia K Sapkota, Z Mao, P Synowicki, D Lieber, M Liu, T Ikezu, V Gautam, ... Journal of Pharmacology and Experimental Therapeutics 356 (3), 702-711, 2016 | 68 | 2016 |
Synthesis and anti-melanogenic activity of hydroxyphenyl benzyl ether analogues K Sapkota, E Roh, E Lee, EM Ha, JH Yang, ES Lee, Y Kwon, Y Kim, Y Na Bioorganic & medicinal chemistry 19 (7), 2168-2175, 2011 | 29 | 2011 |
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors JX Wang, MW Irvine, ES Burnell, K Sapkota, RJ Thatcher, M Li, ... Nature communications 11 (1), 423, 2020 | 27 | 2020 |
GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia K Nakao, M Singh, K Sapkota, BC Hagler, RN Hunter, C Raman, ... Neuropsychopharmacology 45 (13), 2207-2218, 2020 | 25 | 2020 |
Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators G France, R Volianskis, R Ingram, N Bannister, R Rothärmel, MW Irvine, ... Neuropharmacology 202, 108840, 2022 | 22 | 2022 |
The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators K Sapkota, K Dore, K Tang, M Irvine, G Fang, ES Burnell, R Malinow, ... Biochemical pharmacology 159, 140-153, 2019 | 22 | 2019 |
Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives K Sapkota, MW Irvine, G Fang, ES Burnell, N Bannister, A Volianskis, ... Neuropharmacology 125, 64-79, 2017 | 18 | 2017 |
Pananx notoginseng saponins attenuate CCL2-induced cognitive deficits in rats via anti-inflammation and anti-apoptosis effects that involve suppressing over-activation of NMDA … Y Zhou, J Chen, K Sapkota, J Long, Y Liao, J Jiang, B Liang, J Wei, ... Biomedicine & Pharmacotherapy 127, 110139, 2020 | 17 | 2020 |
IL-13 and its genetic variants: effect on current asthma treatments RG Townley, M Sapkota, K Sapkota Discovery medicine 12 (67), 513-523, 2011 | 15 | 2011 |
Effect of IL‐1β and TNF‐αvs IL‐13 on bronchial hyperresponsiveness, β2‐adrenergic responses and cellularity of bronchial alveolar lavage fluid M Horiba, N Qutna, P Gendapodi, S Agrawal, K Sapkota, P Abel, ... Autonomic and Autacoid Pharmacology 31 (3‐4), 37-49, 2011 | 15 | 2011 |
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment H Hagihara, H Shoji, S Hattori, G Sala, Y Takamiya, M Tanaka, M Ihara, ... Elife 12, RP89376, 2024 | 14 | 2024 |
Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid MW Irvine, G Fang, K Sapkota, ES Burnell, A Volianskis, BM Costa, ... European journal of medicinal chemistry 164, 471-498, 2019 | 13 | 2019 |
5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction K Nakao, M Singh, K Sapkota, A Fitzgerald, JJ Hablitz, K Nakazawa Translational Psychiatry 12 (1), 168, 2022 | 12 | 2022 |
Omalizumab for pediatric asthma RG Townley, S Agrawal, K Sapkota Expert Opinion on Biological Therapy 10 (11), 1595-1608, 2010 | 12 | 2010 |
A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors DA Chopra, K Sapkota, MW Irvine, G Fang, DE Jane, DT Monaghan, ... Scientific reports 7 (1), 6933, 2017 | 10 | 2017 |
Systematic analysis of brain lactate and pH levels in 65 animal models related to neuropsychiatric conditions H Hagihara, H Shoji, T Miyakawa, ... bioRxiv, 2021 | 7 | 2021 |
4-Hydroxy-2'-nitrodiphenyl ether analogues as novel tyrosinase inhibitors K Sapkota, EY Lee, JH Yang, YJ Kwon, JW Choi, YH Na Bulletin of the Korean Chemical Society 31 (5), 1319-1325, 2010 | 3 | 2010 |
Maturation of GABAergic Synaptic Transmission From Neocortical Parvalbumin Interneurons Involves N-methyl-D-aspartate Receptor Recruitment of Cav2. 1 Channels M Singh, K Sapkota, K Sakimura, M Kano, RM Cowell, ... Neuroscience 513, 38-53, 2023 | 2 | 2023 |