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Kiran Sapkota, Ph.D.
Kiran Sapkota, Ph.D.
Assistant Professor, UNMC COP Pharmaceutical Sciences
Verified email at unmc.edu
Title
Cited by
Cited by
Year
The origin of NMDA receptor hypofunction in schizophrenia
K Nakazawa, K Sapkota
Pharmacology & therapeutics 205, 107426, 2020
2522020
Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure–Activity Relationships and Mechanisms of Action
ES Burnell, M Irvine, G Fang, K Sapkota, DE Jane, DT Monaghan
Journal of medicinal chemistry 62 (1), 3-23, 2018
692018
GluN2D N-methyl-d-aspartate receptor subunit contribution to the stimulation of brain activity and gamma oscillations by ketamine: implications for schizophrenia
K Sapkota, Z Mao, P Synowicki, D Lieber, M Liu, T Ikezu, V Gautam, ...
Journal of Pharmacology and Experimental Therapeutics 356 (3), 702-711, 2016
682016
Synthesis and anti-melanogenic activity of hydroxyphenyl benzyl ether analogues
K Sapkota, E Roh, E Lee, EM Ha, JH Yang, ES Lee, Y Kwon, Y Kim, Y Na
Bioorganic & medicinal chemistry 19 (7), 2168-2175, 2011
292011
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
JX Wang, MW Irvine, ES Burnell, K Sapkota, RJ Thatcher, M Li, ...
Nature communications 11 (1), 423, 2020
272020
GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia
K Nakao, M Singh, K Sapkota, BC Hagler, RN Hunter, C Raman, ...
Neuropsychopharmacology 45 (13), 2207-2218, 2020
252020
Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators
G France, R Volianskis, R Ingram, N Bannister, R Rothärmel, MW Irvine, ...
Neuropharmacology 202, 108840, 2022
222022
The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators
K Sapkota, K Dore, K Tang, M Irvine, G Fang, ES Burnell, R Malinow, ...
Biochemical pharmacology 159, 140-153, 2019
222019
Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives
K Sapkota, MW Irvine, G Fang, ES Burnell, N Bannister, A Volianskis, ...
Neuropharmacology 125, 64-79, 2017
182017
Pananx notoginseng saponins attenuate CCL2-induced cognitive deficits in rats via anti-inflammation and anti-apoptosis effects that involve suppressing over-activation of NMDA …
Y Zhou, J Chen, K Sapkota, J Long, Y Liao, J Jiang, B Liang, J Wei, ...
Biomedicine & Pharmacotherapy 127, 110139, 2020
172020
IL-13 and its genetic variants: effect on current asthma treatments
RG Townley, M Sapkota, K Sapkota
Discovery medicine 12 (67), 513-523, 2011
152011
Effect of IL‐1β and TNF‐αvs IL‐13 on bronchial hyperresponsiveness, β2‐adrenergic responses and cellularity of bronchial alveolar lavage fluid
M Horiba, N Qutna, P Gendapodi, S Agrawal, K Sapkota, P Abel, ...
Autonomic and Autacoid Pharmacology 31 (3‐4), 37-49, 2011
152011
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
H Hagihara, H Shoji, S Hattori, G Sala, Y Takamiya, M Tanaka, M Ihara, ...
Elife 12, RP89376, 2024
142024
Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid
MW Irvine, G Fang, K Sapkota, ES Burnell, A Volianskis, BM Costa, ...
European journal of medicinal chemistry 164, 471-498, 2019
132019
5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction
K Nakao, M Singh, K Sapkota, A Fitzgerald, JJ Hablitz, K Nakazawa
Translational Psychiatry 12 (1), 168, 2022
122022
Omalizumab for pediatric asthma
RG Townley, S Agrawal, K Sapkota
Expert Opinion on Biological Therapy 10 (11), 1595-1608, 2010
122010
A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors
DA Chopra, K Sapkota, MW Irvine, G Fang, DE Jane, DT Monaghan, ...
Scientific reports 7 (1), 6933, 2017
102017
Systematic analysis of brain lactate and pH levels in 65 animal models related to neuropsychiatric conditions
H Hagihara, H Shoji, T Miyakawa, ...
bioRxiv, 2021
72021
4-Hydroxy-2'-nitrodiphenyl ether analogues as novel tyrosinase inhibitors
K Sapkota, EY Lee, JH Yang, YJ Kwon, JW Choi, YH Na
Bulletin of the Korean Chemical Society 31 (5), 1319-1325, 2010
32010
Maturation of GABAergic Synaptic Transmission From Neocortical Parvalbumin Interneurons Involves N-methyl-D-aspartate Receptor Recruitment of Cav2. 1 Channels
M Singh, K Sapkota, K Sakimura, M Kano, RM Cowell, ...
Neuroscience 513, 38-53, 2023
22023
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Articles 1–20