Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden, C Hammack, ... Cell 165 (5), 1238-1254, 2016 | 2137 | 2016 |
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ... Cell 180 (1), 188-204. e22, 2020 | 839 | 2020 |
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ... Nature medicine 22 (10), 1101-1107, 2016 | 713 | 2016 |
Temporal control of mammalian cortical neurogenesis by m6A methylation KJ Yoon, FR Ringeling, C Vissers, F Jacob, M Pokrass, D Jimenez-Cyrus, ... Cell 171 (4), 877-889. e17, 2017 | 707 | 2017 |
Generation of human brain region–specific organoids using a miniaturized spinning bioreactor X Qian, F Jacob, MM Song, HN Nguyen, H Song, G Ming Nature protocols 13 (3), 565, 2018 | 468 | 2018 |
Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium F Jacob, SR Pather, WK Huang, F Zhang, SZH Wong, H Zhou, B Cubitt, ... Cell stem cell 27 (6), 937-950. e9, 2020 | 420 | 2020 |
Sliced human cortical organoids for modeling distinct cortical layer formation X Qian, Y Su, CD Adam, AU Deutschmann, SR Pather, EM Goldberg, ... Cell stem cell 26 (5), 766-781. e9, 2020 | 384 | 2020 |
Using brain organoids to understand Zika virus-induced microcephaly X Qian, HN Nguyen, F Jacob, H Song, G Ming Development 144 (6), 952-957, 2017 | 243 | 2017 |
Zika-virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins KJ Yoon, G Song, X Qian, J Pan, D Xu, HS Rho, NS Kim, C Habela, ... Cell stem cell 21 (3), 349-358. e6, 2017 | 212 | 2017 |
Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin A Sada, F Jacob, E Leung, S Wang, BS White, D Shalloway, T Tumbar Nature cell biology 18 (6), 619-631, 2016 | 203 | 2016 |
Molecular landscapes of human hippocampal immature neurons across lifespan Y Zhou, Y Su, S Li, BC Kennedy, DY Zhang, AM Bond, Y Sun, F Jacob, ... Nature 607 (7919), 527-533, 2022 | 199 | 2022 |
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes M Song, X Yang, X Ren, L Maliskova, B Li, IR Jones, C Wang, F Jacob, ... Nature genetics 51 (8), 1252-1262, 2019 | 176 | 2019 |
DISC1 regulates neurogenesis via modulating kinetochore attachment of Ndel1/Nde1 during mitosis F Ye, E Kang, C Yu, X Qian, F Jacob, C Yu, M Mao, RYC Poon, J Kim, ... Neuron 96 (5), 1041-1054. e5, 2017 | 164 | 2017 |
Generation and biobanking of patient-derived glioblastoma organoids and their application in CAR T cell testing F Jacob, G Ming, H Song Nature protocols 15 (12), 4000-4033, 2020 | 135 | 2020 |
Structural and functional integration of human forebrain organoids with the injured adult rat visual system D Jgamadze, JT Lim, Z Zhang, PM Harary, J Germi, K Mensah-Brown, ... Cell Stem Cell 30 (2), 137-152. e7, 2023 | 78 | 2023 |
Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR-mutant glioblastoma I Makhlin, RD Salinas, D Zhang, F Jacob, G Ming, H Song, D Saxena, ... CNS oncology 8 (3), CNS43, 2019 | 48 | 2019 |
Building the brain from scratch: Engineering region-specific brain organoids from human stem cells to study neural development and disease F Jacob, JG Schnoll, H Song, G Ming Current topics in developmental biology 142, 477-530, 2021 | 26 | 2021 |
A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment X Lin, W Wang, M Yang, N Damseh, MML de Sousa, F Jacob, A Lång, ... Genome Biology 24 (1), 216, 2023 | 5* | 2023 |
Modeling neurological disease using human stem cell-derived microglia-like cells transplanted into rodent brains F Jacob, ML Bennett Lab animal 49 (2), 49-51, 2020 | 4 | 2020 |
Volumetric analysis of spheno-orbital meningiomas: prognostic correlation and a compartmentalized approach YM Zohdy, F Jacob, M Agam, A Alawieh, D Bray, JMR Barbero, SA Argaw, ... Neurosurgery 94 (4), 736-744, 2024 | 3 | 2024 |